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ChemicalBook >> CAS DataBase List >>1,8-NAPHTHYRIDIN-2-AMINE

1,8-NAPHTHYRIDIN-2-AMINE

1,8-NAPHTHYRIDIN-2-AMINE Structure
1,8-NAPHTHYRIDIN-2-AMINE structure
CAS No.
15992-83-3
Chemical Name:
1,8-NAPHTHYRIDIN-2-AMINE
Synonyms
1,8-PHTHYRIDIN-2-AMINE;8-naphthyridin-2-amine;1,8-NAPHTHYRIDIN-2-AMINE;1,8-Naphthyridin-2-amine - [D94656]
CBNumber:
CB9425792
Molecular Formula:
C8H7N3
Molecular Weight:
145.16
MDL Number:
MFCD01250851
MOL File:
15992-83-3.mol
MSDS File:
SDS
Last updated:2026-05-28 04:25:48
Product description Number Pack Size Price
1,8-Naphthyridin-2-amine 97% OR928440 50mg $25
1,8-Naphthyridin-2-amine 97% OR928440 100mg $30
1,8-Naphthyridin-2-amine 97% OR928440 250mg $37
1,8-Naphthyridin-2-amine 97% OR928440 1g $86
1,8-Naphthyridin-2-amine 97% OR928440 5g $309
Request For Quotation

1,8-NAPHTHYRIDIN-2-AMINE Properties

Melting point 139-141 °C(Solv: ethanol (64-17-5))
Boiling point 322.6±22.0 °C(Predicted)
Density 1.292±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form solid
pka 5.09±0.30(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2933998090

1,8-NAPHTHYRIDIN-2-AMINE price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR928440 1,8-Naphthyridin-2-amine 97% 15992-83-3 50mg $25 2026-06-04 Buy
Apolloscientific OR928440 1,8-Naphthyridin-2-amine 97% 15992-83-3 100mg $30 2026-06-04 Buy
Apolloscientific OR928440 1,8-Naphthyridin-2-amine 97% 15992-83-3 250mg $37 2026-06-04 Buy
Apolloscientific OR928440 1,8-Naphthyridin-2-amine 97% 15992-83-3 1g $86 2026-06-04 Buy
Apolloscientific OR928440 1,8-Naphthyridin-2-amine 97% 15992-83-3 5g $309 2026-06-04 Buy
Product number Packaging Price Buy
OR928440 50mg $25 Buy
OR928440 100mg $30 Buy
OR928440 250mg $37 Buy
OR928440 1g $86 Buy
OR928440 5g $309 Buy

1,8-NAPHTHYRIDIN-2-AMINE Chemical Properties,Uses,Production

Synthesis

2,6-Diaminopyridine

141-86-6

1,1,3,3-Tetramethoxypropane

102-52-3

1,8-NAPHTHYRIDIN-2-AMINE

15992-83-3

To a reaction flask equipped with a stirrer was added 107 g of 2,6-diaminopyridine and 1070 ml of phosphoric acid, to which 241 g of 1,1,3,3-tetramethoxypropane was slowly added dropwise at room temperature. Subsequently, the reaction mixture was heated in an oil bath maintaining the internal temperature at 70-75°C and the reaction lasted for 40 minutes. Upon completion of the reaction, the mixture was poured into 5 liters of ice-cooled aqueous 5 M sodium hydroxide solution and the pH was adjusted to greater than 10. The precipitate was collected by filtration and washed twice with 200 ml of water. The filtrate was extracted twice with dichloromethane, 300 ml each. the combined dichloromethane phases were dried over 100 g of anhydrous sodium sulfate, filtered and concentrated to dryness. The crude product was purified by column chromatography using alumina as stationary phase and a solvent mixture of dichloromethane and methanol (100:1, v/v) as eluent, resulting in 102 g of red solid 1,8-naphthyridin-2-amine in 72% yield and 96% HPLC purity.

References

[1] Patent: CN105399739, 2016, A. Location in patent: Paragraph 0019; 0020
[2] Angewandte Chemie - International Edition, 2017, vol. 56, # 12, p. 3349 - 3353
[3] Angew. Chem., 2017, vol. 129, p. 3397 - 3401,5
[4] Journal of Heterocyclic Chemistry, 1997, vol. 34, # 3, p. 765 - 771

1,8-NAPHTHYRIDIN-2-AMINE Preparation Products And Raw materials

Raw materials

2,6-Diaminopyridine 3-Dimethylaminoacrolein 1,1,3,3-Tetramethoxypropane

Preparation Products

1,8-NAPHTHYRIDIN-2-AMINE Suppliers

Global( 84)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30224 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43333 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Zjartspharm Co., Ltd 		+8615068876005 jocelynpan@zjarts.com China 9960 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131956 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15838 69
Supplier Advantage
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Career Henan Chemica Co 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Aladdin Scientific 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Zjartspharm Co., Ltd 		58
Amadis Chemical Company Limited 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69

View Lastest Price from 1,8-NAPHTHYRIDIN-2-AMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,8-NAPHTHYRIDIN-2-AMINE pictures 2020-02-02 1,8-NAPHTHYRIDIN-2-AMINE
15992-83-3
 $1.00 1KG 98% HPLC 10 tons Career Henan Chemical Co

1,8-NAPHTHYRIDIN-2-AMINE Spectrum

1,8-NAPHTHYRIDIN-2-AMINE(15992-83-3)1HNMR

15992-83-3(1,8-NAPHTHYRIDIN-2-AMINE)Related Search:

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7-MORPHOLINO-2,4-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDINE N-(4-CHLOROPHENYL)-5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-AMINE N-(4-PHENOXYPHENYL)-5,7-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDIN-2-AMINE

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1,8-NAPHTHYRIDIN-2-AMINE 8-naphthyridin-2-amine 1,8-PHTHYRIDIN-2-AMINE 1,8-Naphthyridin-2-amine - [D94656] 15992-83-3