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4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE

CAS No.
343788-69-2
Chemical Name:
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
Synonyms
4-Amino-1-Boc-4-methylpip...;TERT-BUTYL-4-AMINO-4-METHYLPIP;1-Boc-4-AMino-4-Methylpiperidine;4-Amino-1-Boc-4-methylpiperidine;N-Boc-4-amino-4-methylpiperidine;4-AMINO-4-METHYL-1-BOC-PIPERIDINE;1-BOC-4-AMINO-4-METHYL PIPERADINE;4-AMINO-4-METHYL-N-BOC-PIPERIDINE;4-Amino-1-N-boc-4-methyl-piperidine;butyl 4-aMino-4-Methylpiperidine-1-carboxylate
CBNumber:
CB9441604
Molecular Formula:
C11H22N2O2
Molecular Weight:
214.3
MDL Number:
MFCD03265497
MOL File:
343788-69-2.mol
Last updated:2025-07-24 18:13:44
Product description Number Pack Size Price
tert-Butyl 4-Amino-4-methylpiperidine-1-carboxylate min. 95.0 % A3491 1G $141
tert-Butyl4-Amino-4-methylpiperidine-1-carboxylate B415188 250mg $90
1-Boc-4-Amino-4-methylpiperidine W5593 1g $122
4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine FA148944 500mg $125
4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine FA148944 250mg $80
More product size

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Properties

Boiling point 283℃
Density 1.017
Flash point 125℃
storage temp. 2-8°C(protect from light)
pka 9.77±0.20(Predicted)
Appearance Colorless to light yellow Solid-Liquid Mixture

SAFETY

Risk and Safety Statements

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A3491 tert-Butyl 4-Amino-4-methylpiperidine-1-carboxylate min. 95.0 % 343788-69-2 1G $141 2025-07-31 Buy
TRC B415188 tert-Butyl4-Amino-4-methylpiperidine-1-carboxylate 343788-69-2 250mg $90 2021-12-16 Buy
AK Scientific W5593 1-Boc-4-Amino-4-methylpiperidine 343788-69-2 1g $122 2021-12-16 Buy
Biosynth Carbosynth FA148944 4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine 343788-69-2 500mg $125 2021-12-16 Buy
Biosynth Carbosynth FA148944 4-Amino-1-N-butoxycarbonyl-4-methyl-piperidine 343788-69-2 250mg $80 2021-12-16 Buy
Product number Packaging Price Buy
A3491 1G $141 Buy
B415188 250mg $90 Buy
W5593 1g $122 Buy
FA148944 500mg $125 Buy
FA148944 250mg $80 Buy

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Chemical Properties,Uses,Production

Chemical Properties

White powder

Synthesis

4-BENZYLOXY-CARBONYL-AMINO-1-N-BUTOXY-CARBONYL-4-METHYL PIPERIDINE

236406-14-7

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE

343788-69-2

General procedure for the synthesis of tert-butyl 4-amino-4-methylpiperidine-1-carboxylate from the compound (CAS: 236406-14-7): a mixture of the compound of formula LE (2.48 g, 7.11 mmol) with 10% palladium carbon (200 mg, Sigma-Aldrich) in methanol (20 mL) was subjected to an atmosphere of hydrogen at about 250 °C The reaction was stirred for 16 hours. Upon completion of the reaction, the Pd/C catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to give 1.37 g of the compound of formula LF as a light-colored viscous oil (90.2% yield). The structure of tert-butyl 4-amino-4-methylpiperidine-1-carboxylate, compound of formula LF, was confirmed using 1H NMR. The 1H NMR data of compound LF were as follows: δH (400 MHz, CDCl3): 3.47-3.49 (4H, m), 1.47-1.61 (4H, m), 1.46 (9H, s), 1.31-1.42 (2H, m), 1.15 (3H, s).

References

[1] Patent: WO2008/89201, 2008, A2. Location in patent: Page/Page column 234-235
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 12, p. 5901 - 5921
[3] Patent: WO2006/38006, 2006, A2. Location in patent: Page/Page column 26-27
[4] Patent: WO2009/116067, 2009, A2. Location in patent: Page/Page column 139

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View Lastest Price from 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE pictures 2019-07-06 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE
343788-69-2
US $1.00 / kg 1kg 98% 200 Career Henan Chemical Co

4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE Spectrum

4-Amino-1-Boc-4-methylpiperidine 4-Amino-1-Boc-4-methylpip... 1-Boc-4-AMino-4-Methylpiperidine 1-Piperidinecarboxylic acid, 4-aMino-4-Methyl-, 1,1-diMethylethyl ester 1-(tert-Butoxycarbonyl)-4-amino-4-methylpiperidine N-Boc-4-amino-4-methylpiperidine 4-AMino-4-Methyl-1-piperidinecarboxylic acid tert-butyl ester butyl 4-aMino-4-Methylpiperidine-1-carboxylate 1-BOC-4-AMINO-4-METHYL PIPERADINE TERT-BUTYL 4-AMINO-4-METHYLPIPERIDINE-1-CARBOXYLATE 4-AMINO-4-METHYL-1-BOC-PIPERIDINE 4-AMINO-1-N-TERT-BUTYLOXYCARBONYL-4-METHYL-PIPERIDINE 4-Amino-1-N-boc-4-methyl-piperidine TERT-BUTYL-4-AMINO-4-METHYLPIP 4-AMINO-4-METHYL-N-BOC-PIPERIDINE 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE 343788-69-2 43788-69-2