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ChemicalBook >> CAS DataBase List >>N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide

N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide

N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide Structure
N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide structure
CAS No.
300803-79-6
Chemical Name:
N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide
Synonyms
WAY-299017;PI3Kα-IN-11;N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide;3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-2-oxo-N-(phenylmethyl)-
CBNumber:
CB94461569
Molecular Formula:
C17H14N2O3
Molecular Weight:
294.3
MDL Number:
MOL File:
300803-79-6.mol
Last updated:2025-04-18 09:53:09
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N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide Properties

Boiling point 622.4±55.0 °C(Predicted)
Density 1.363±0.06 g/cm3(Predicted)
pka 4.50±1.00(Predicted)
form Solid
color White to light yellow

N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide Chemical Properties,Uses,Production

Uses

PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].

IC 50

PI3Kα

References

[1] Sabbah DA, et al.N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα). Bioorg Med Chem. 2012 Dec 15;20(24):7175-83. DOI:10.1016/j.bmc.2012.09.059

N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 15317229551 15151849396@163.com China 998 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10523 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 4763 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 024-024-024-88590548 18341751992 757984502@qq.com China 929 58
Shandong Mopai Biotechnology Co., Ltd 13053322091 13053322091 admin@mopaikeji.com China 4241 58
ZhengZhou Edward Biology Co.,Ltd 13298105281 13298105281 1522334715@qq.com China 7507 58
Supplier Advantage
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd 58
cjbscvictory 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58
Shandong Mopai Biotechnology Co., Ltd 58
ZhengZhou Edward Biology Co.,Ltd 58
N-benzyl-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide WAY-299017 3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-2-oxo-N-(phenylmethyl)- PI3Kα-IN-11 300803-79-6