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4-(4-Hydroxyphenyl)cyclohexanone

4-(4-Hydroxyphenyl)cyclohexanone structure

CAS No.: 105640-07-1

Chemical Name:: 4-(4-Hydroxyphenyl)cyclohexanone

Synonyms: HOPCK;LABOTEST-BB LT00847424;4-(4-Oxocyclohexyl)phenol;4-(4-Hydroxyphenyl)cyclohexa;4-(P-Hydroxyphenyl)Cyclohexane;4-(P-HYDROXYPHENYL)CYCLOHEXANONE;4-(4-HYDROXYPHENYL)CYCLOHEXANONE;4-(4'-Hydroxyphenyl)cyclohexanone;4-(4'-HYDROXYPHENYL)-CYCLOHEXANONE;Cyclohexanone,4-(4-hydroxyphenyl)-

CBNumber:: CB9448209

Molecular Formula:: C12H14O2

Molecular Weight:: 190.24

MDL Number:: MFCD00210693

MOL File:: 105640-07-1.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:43

Product description	Number	Pack Size	Price
4-(4-Hydroxyphenyl)cyclohexanone ≥97.0% (HPLC)	56117	25g	$93.5
4-(4-Hydroxyphenyl)cyclohexanone >95.0%(GC)	H1316	5g	$29
4-(4-Hydroxyphenyl)cyclohexanone >95.0%(GC)	H1316	25g	$81
4-(4-Hydroxyphenyl)cyclohexanone	H973025	100mg	$60
4-(4-Hydroxyphenyl)cyclohexanone 98%	JK554157	1g	$42
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4-(4-Hydroxyphenyl)cyclohexanone Properties

Melting point	170-175 °C
Boiling point	357.2±42.0 °C(Predicted)
Density	1.149±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	10.10±0.30(Predicted)
color	White to Almost white
BRN	3269332
InChI	InChI=1S/C12H14O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-2,5-6,10,13H,3-4,7-8H2
InChIKey	SLJYPZJZQIHNGU-UHFFFAOYSA-N
SMILES	C1(=O)CCC(C2=CC=C(O)C=C2)CC1
CAS DataBase Reference	105640-07-1(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

WGK Germany

HS Code

29145090

NFPA 704

	1
1		0

4-(4-Hydroxyphenyl)cyclohexanone price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	56117	4-(4-Hydroxyphenyl)cyclohexanone ≥97.0% (HPLC)	105640-07-1	25g	$93.5	2025-07-31	Buy
TCI Chemical	H1316	4-(4-Hydroxyphenyl)cyclohexanone >95.0%(GC)	105640-07-1	5g	$29	2025-07-31	Buy
TCI Chemical	H1316	4-(4-Hydroxyphenyl)cyclohexanone >95.0%(GC)	105640-07-1	25g	$81	2025-07-31	Buy
TRC	H973025	4-(4-Hydroxyphenyl)cyclohexanone	105640-07-1	100mg	$60	2021-12-16	Buy
Frontier Specialty Chemicals	JK554157	4-(4-Hydroxyphenyl)cyclohexanone 98%	105640-07-1	1g	$42	2021-12-16	Buy

Product number	Packaging	Price	Buy
56117	25g	$93.5	Buy
H1316	5g	$29	Buy
H1316	25g	$81	Buy
H973025	100mg	$60	Buy
JK554157	1g	$42	Buy

4-(4-Hydroxyphenyl)cyclohexanone Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Synthesis

82240-03-7

105640-07-1

General procedure: 56.1 g of 4-(4-benzyloxyphenyl)cyclohexanone, 336.6 mL of tetrahydrofuran and 2.8 g of 5% Pd/C catalyst were sequentially added to a 500 mL three-neck flask. The atmosphere in the flask was replaced three times with hydrogen and the hydrogenation reaction was subsequently carried out under hydrogen atmosphere. The reaction system was heated to 40-45 °C in a water bath and maintained at this temperature until completion of the reaction (reaction endpoint determination criterion: 4-(4-benzyloxyphenyl)cyclohexanone residue less than 1%, specifically 0.5687%). Upon completion of the reaction, the heating and hydrogen supply were stopped. Post-treatment steps: the reaction mixture was filtered and the filter cake was washed twice with tetrahydrofuran, 5 mL each time. the filtrates were combined and concentrated under reduced pressure at 35-45 °C and -0.08 MPa to -0.09 MPa until no fraction flowed out, yielding a white solid. To this solid was added 195 mL of ethanol and heated to reflux (60-65 °C) for 1-2 h until completely dissolved and clarified. The solution was then cooled to -25 to -15°C and left to crystallize for 8 hours. The crystals were collected by filtration and washed twice with ethanol, 5 mL each time.The filter cake was dried under reduced pressure at 45-55 °C, -0.08 MPa to -0.09 MPa for 10 h to give 32 g of white to off-white powdery solid, i.e., the target product 4-(4-hydroxyphenyl)cyclohexanone.

References

[1] Patent: CN106892805, 2017, A. Location in patent: Paragraph 0034; 0035; 0036

4-(4-Hydroxyphenyl)cyclohexanone Preparation Products And Raw materials

Raw materials

4-[P-(BENZYLOXY)PHENYL]CYCLOHEXANONE Activated carbon Hydrogen Tetrahydrofuran Palladium

Preparation Products

4-(4-Isopropoxyphenyl)cyclohexanone 4-(4-methoxyphenyl)cyclohexanone

4-(4-Hydroxyphenyl)cyclohexanone Suppliers

Global( 203)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8772	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	+8613288715578	sales@sichuanzyyt.com	China	12247	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29734	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
QINGDAO HONG JIN CHEMCIAL CO.,LTD.	532-83657313 18663969289;	hjt@hong-jin.com	China	227	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Sichuan Zhuoyu Yantang Technology Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
career henan chemical co	58
QINGDAO HONG JIN CHEMCIAL CO.,LTD.	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 4-(4-Hydroxyphenyl)cyclohexanone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-17	4-(4-Hydroxyphenyl)cyclohexanone 105640-07-1	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-08-08	4-(4-Hydroxyphenyl)cyclohexanone 105640-07-1	US $0.00 / KG	1KG	99%	50000KG/month	Sichuan Zhuoyu Yantang Technology Co., Ltd.
2025-06-27	4-(4-Hydroxyphenyl)cyclohexanone 105640-07-1	US $0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

4-(4-Hydroxyphenyl)cyclohexanone
105640-07-1
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-(4-Hydroxyphenyl)cyclohexanone
105640-07-1
US $0.00 / KG
99%
Sichuan Zhuoyu Yantang Technology Co., Ltd.

4-(4-Hydroxyphenyl)cyclohexanone
105640-07-1
US $0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

4-(4-Hydroxyphenyl)cyclohexanone Spectrum

4-(4-Hydroxyphenyl)cyclohexanone(105640-07-1)¹HNMR

105640-07-1(4-(4-Hydroxyphenyl)cyclohexanone)Related Search:

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4-(4-Oxocyclohexyl)phenol LABOTEST-BB LT00847424 4-(P-HYDROXYPHENYL)CYCLOHEXANONE 4-(4'-HYDROXYPHENYL)-CYCLOHEXANONE 4-(4-HYDROXYPHENYL)CYCLOHEXANONE HOPCK 4-(4-hydroxyphenyl)cyclohexan-1-one 4-(4-Hydroxyphenyl)cyclohexa 4-(4-Hydroxyphenyl)cyclohexanone >=97.0% (HPLC) Cyclohexanone,4-(4-hydroxyphenyl)- 4-(4-hydroxyphenyl)-1-cyclohexanone 4-(4-Hydroxyphenyl)cyclohexanone> 4-(P-Hydroxyphenyl)Cyclohexane 4-(4'-Hydroxyphenyl)cyclohexanone 105640-07-1 150640-07-1 Building Blocks C11 to C12 Carbonyl Compounds Organic Building Blocks Ketones