Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt)
- Synonyms
- α-Secretase Substrate I（MCA-DNP pair）;Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt)
- CBNumber:
- CB94666133
- Molecular Formula:
- C73H95N17O18
- Molecular Weight:
- 1498.6385
- MDL Number:
- MOL File:
- Mol file
Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt) price More Price(1)
Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Mca-HQKLVFFA-K(Dnp)-NH2 is a fluorogenic substrate for α-secretase.1 Upon cleavage by α-secretase, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify α-secretase activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.WARNING This product is not for human or veterinary use.
References
[1] HIROAKI FUKUMOTO. A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer’s disease.[J]. Journal of Neuroscience, 2010, 30 33: 11157-11166. DOI: 10.1523/jneurosci.2884-10.2010
Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Mca-HQKLVFFA-K(Dnp)-NH2 (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Zhiyun Biotechnology Co., Ltd | 13119135307 | China | 2766 | 58 | |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
