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Hederacoside C

Hederacoside C structure

CAS No.: 14216-03-6

Chemical Name:: Hederacoside C

Synonyms: Ivy C;Hederacol;Aids086294;Aids-086294;Tauroside H2;Hederoside H1;HEDERACOSIDE C;Glycoside L-H2;Ivy glycoside C;Akebia saponin pk

CBNumber:: CB9477403

Molecular Formula:: C59H96O26

Molecular Weight:: 1221.38

MDL Number:: MFCD00198062

MOL File:: 14216-03-6.mol

Last updated:2026-01-21 16:49:52

Product description	Number	Pack Size	Price
Hederacoside C phyproof^® Reference Substance	PHL89221	20 mg	$593
Hederacoside C analytical standard	97151	50mg	$166
Hederacoside C primary pharmaceutical reference standard	00930585	10mg	$660
Hederacoside C analytical standard	79737	10mg	$324
Hederacoside C	H1809	50MG	$180
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Hederacoside C Properties

Melting point	222 °C (dec.)(lit.)
Density	1.48±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,2-8°C
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Sparingly)
pka	12.50±0.70(Predicted)
form	Solid
color	White to Pale Beige
BRN	4229541
Stability	Hygroscopic
Major Application	food and beverages
InChIKey	RYHDIBJJJRNDSX-MCGLQMIESA-N
LogP	4.520 (est)
FDA UNII	2608B2L1BQ
UNSPSC Code	85151701
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P501

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

Safety Statements

22-24/25

RIDADR

UN 2811 6.1/PG 3

WGK Germany

10-23

HS Code

29389090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

NFPA 704

	0
2		0

Hederacoside C price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHL89221	Hederacoside C phyproof^® Reference Substance	14216-03-6	20 mg	$593	2025-07-31	Buy
Sigma-Aldrich	97151	Hederacoside C analytical standard	14216-03-6	50mg	$166	2025-07-31	Buy
Sigma-Aldrich	00930585	Hederacoside C primary pharmaceutical reference standard	14216-03-6	10mg	$660	2025-07-31	Buy
Sigma-Aldrich	79737	Hederacoside C analytical standard	14216-03-6	10mg	$324	2022-05-15	Buy
TCI Chemical	H1809	Hederacoside C	14216-03-6	50MG	$180	2025-07-31	Buy

Product number	Packaging	Price	Buy
PHL89221	20 mg	$593	Buy
97151	50mg	$166	Buy
00930585	10mg	$660	Buy
79737	10mg	$324	Buy
H1809	50MG	$180	Buy

Hederacoside C Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

solubilizer, bio-availability enhancer in oral suspensions, capsules

Uses

Hederacoside C is a Hedera helix leaf which has been used in botanical drug formulations to treat acute respiratory infection and bronchitis. Anti-myocardial.

Definition

ChEBI: A triterpenoid saponin with hederagenin as the aglycone part. It has been isolated from the stem bark of Kalopanax pictus.

Synthesis

Take dry manipulation ivy stems and leaves 500g, crushed, with 30% ethanol 4000mL, 2000mL at 80 ?? successively heated reflux for two times, reflux time were 3 hours, 2 hours. Combine the two extracts, decompression recovery of solvent, get ivy crude extract. The crude extract of ivy was dissolved in 150 mL of water in an ultrasonic generator, and the aqueous solution was extracted with equal volumes of ether, ethyl acetate and n-butanol for three times, respectively. The three n-butanol extracts were combined, concentrated under reduced pressure to near dryness and dissolved in 80 mL of 95% ethanol. Gradually add ethyl acetate to the 95% ethanol solution under stirring until no more precipitate was produced, and then collect the precipitate by filtration after 2 hours of standing. The precipitate was dissolved with a small amount of methanol and eluted by column chromatography using silica gel as stationary phase and a mixture of chloroform:methanol equal to 65:35 as mobile phase. The eluent was collected, and the collected eluent containing ivyoside C was concentrated and freeze-dried to obtain ivyoside C1.0759 g, and the content of ivyoside C was 98.2% as detected by high performance liquid chromatography.

in vivo

Hederacoside C (0.625, 1.25, 2.5 mg/kg, intraperitoneally injected for 7 consecutive days) can alleviate TNBS-induced enteritis^[1].
Hederacoside C (5, 10, 50 mg/kg, intraperitoneally injected for 3 consecutive times for 8 h) can attenuate the breast lesions caused by Staphylococcus aureus^[2].

Animal Model:	TNBS-induced colitis in rat^[1]
Dosage:	0.625, 1.25, 2.5 mg/kg
Administration:	i.p. for 7 days
Result:	Decreased the levels of inflammatory cytokines, including TNF-α, IL-6, IL-1β, CXCL-1, CXCL-2, and CXCL-5. Reduced cell apoptosis in TNBS-induced colitis. Reduced Bax/Bcl-2 ratio, cleaved caspase 3, and p53 protein levels in a dose-dependent manner.

Hederacoside C synthesis

Synthesis of Hederacoside C from 3β-[(2-O-α-L-Rhamnopyranosyl-α-L-arabinopyranosyl)oxy]-23-hydroxyoleana-12-ene-28-oic acid 6-O-(4-O-α-L-rhamnopyranosyl-6-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranosyl ester

Hederacoside C Preparation Products And Raw materials

Raw materials

Preparation Products

Hederacoside C Suppliers

Global( 262)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	3751	58
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	997	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20129	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29834	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	+8613815430202	sale02@cqherb.com	CHINA	376	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58

Supplier	Advantage
Chengdu Biopurify Phytochemicals Ltd.	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
NanJing Spring & Autumn Biological Engineering CO., LTD.	58
Standardpharm Co. Ltd.	58
BOC Sciences	58
Shanghai Standard Technology Co., Ltd.	58

View Lastest Price from Hederacoside C manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-21	Ivy Leaf Extract 14216-03-6	US $10.00 / kg	1kg	Hederacoside C 3%	10000	Changsha Staherb Natural Ingredients Co., Ltd.
2026-01-21	Hederacoside C 14216-03-6	US $65.00-46.00 / mg		99.93%	10g	TargetMol Chemicals Inc.
2025-09-25	Hederacoside C 14216-03-6	US $6.00-0.20 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

Ivy Leaf Extract
14216-03-6
US $10.00 / kg
Hederacoside C 3%
Changsha Staherb Natural Ingredients Co., Ltd.

Hederacoside C
14216-03-6
US $65.00-46.00 / mg
99.93%
TargetMol Chemicals Inc.

Hederacoside C
14216-03-6
US $6.00-0.20 / KG
99%
Henan Fengda Chemical Co., Ltd

Hederacoside C Spectrum

Hederacoside C(14216-03-6)¹HNMR

14216-03-6(Hederacoside C)Related Search:

Diethylstilbestrol beta-Amyrin ETHYL 3,5,5-TRIMETHYLHEXANOATE CIS-13-DOCOSENOL PETROSELINIC ACID

1-MONOARACHIDIN GLYCEROL MONOISOSTEARATE Butyl oleanolate Ethyl (3beta)-3-hydroxyolean-12-en-28-oate Hederagenin

2-MONOSTEARIN 4-TERT-BUTYLCYCLOHEXANECARBOXYLIC ACID Erythrodiol Methyl oleanolate α-Hederin

Saponin aggreceride A METHYL PRISTANATE

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KIZUTA SAPONIN K(12 HEDERACOSIDE C WITH HPLC Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl]oxy]-23-hydroxy-, O-6-deoxy-alpha-l-mannopyranosyl-(1->4)-O-beta-d-glucopyranosyl-(1->6)-beta-d-glucopyranosyl ester, (3beta,4alpha)- kalopanax saponin B HEDERACOSIDE C (3beta,4alpha)-3-[[2-O-(6-Deoxy-alpha-l-mannopyranosyl)-alpha-l-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid O-6-deoxy-alpha-l-mannopyranosyl-(1->4)-O-beta-d-glucopyranosyl-(1->6)-beta-d-glucopyranosyl ester Hederacoside c, froM Hedera nepalensis 4)-O-b-D-glucopyranosyl-(1® 6)-b-D-glucopyranosyl ester, (3b,4a)- Olean-12-en-28-oicacid, 3-[[2-O-(6-deoxy-a-L-Mannopyranosyl)-a-L-arabinopyranosyl]oxy]-23-hydroxy-, O-6-deoxy-a-L-Mannopyranosyl-(1® 3-[[2-O-(α-L-Rhamnopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid 6-O-[4-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester 3-O-α-L-Rhamnopyranosyl(1→2)-α-L-arabinopyranosylhederagenin 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl Aids086294 Aids-086294 Akebia saponin pk Glycoside L-H2 Hederoside H1 Olean-12-en-28-oic acid, 3-[[2-o-(6-deoxy-.alpha.-L-mannopyranosyl)-.alpha.-L-arabinopyranosyl]oxy]-23-hydroxy-, o-6-deoxy-.alpha.-L-mannopyranosyl-(1.fwdarw.4)-o-.beta.-D-glucopyranosyl-(1.fwdarw.6)-.beta.-D-glucopyranosyl ester, (3.beta.,4.alpha.)- Astrantiasaponin H Hederacaucaside D Hederacol Pericarpsasaponin Pk Pulsatillasaponin F Pulsatillasaponin II Tauroside H2 Hederacoside c, 98%, from Hedera nepalensis Hederacoside C (Kalopanaxsaponin B) Ivy glycoside C Keywords ivy extract total Ivy glycoside Hederacoside C 14216-03-6 (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10-(((2S,3R,4S,5S)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-py Hederacoside CQ: What is Hederacoside C Q: What is the CAS Number of Hederacoside C Q: What is the storage condition of Hederacoside C Q: What are the applications of Hederacoside C (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10-(((2S,3R,4S,5S)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β,4α)- Ivy C Hederacoside C-RM Hederacoside C, 10 mM in DMSO 14216-03-6 C59H96O26 Analytical Standards Alphabetic Analytical Chromatography Product Catalog HA -HT chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract AliphaticAnalytical Standards Herbal DrugsChromatography Alcohols Chemical Class EstersAlphabetic H HA -HTChemical Class Heterocyclics