Apraglutide
- CAS No.
- 1295353-98-8
- Chemical Name:
- Apraglutide
- Synonyms
- FE 203799;Apraglutide;Apraglutide,Apraglutide;Apraglutide (FE 203799)
- CBNumber:
- CB94844469
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| form | Solid |
|---|---|
| color | White to off-white |
| Sequence | His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-{Nle}-{d-Phe}-Thr-Ile-Leu-Asp-Leu-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-NH2 |
| FDA UNII | CVQ1IAY2G6 |
Apraglutide Chemical Properties,Uses,Production
Uses
Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1].
in vivo
Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7[1].
| Animal Model: | NewbornDuroc piglets, 2–5 days old and weighing between 2-2.6 kg[1]. |
| Dosage: | 5 mg/kg/dose. |
| Administration: | Subcutaneously, twice on days 0 and 4 postsurgery. |
| Result: | On day 7, treated piglets were healthy, had significant lower fecal fat and energy losses and exhibited intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth. |
References
[1] Slim GM, et al. Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum. JPEN J Parenter Enteral Nutr. 2019 Jan 6. DOI:10.1002/jpen.1500
Apraglutide Preparation Products And Raw materials
Raw materials
Preparation Products
Apraglutide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
| Shanghai Weiyuxi Biotechnology Co. , Ltd. | +86-8621-57760585 +8619299292982 | api-specialist@wayxbio.com | China | 245 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 10997 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
| Hangzhou Peptide Biochem Co.,Ltd | 0571-89197072; 18668118770 | linda@peptide-china.com | China | 235 | 56 |
View Lastest Price from Apraglutide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-08 | Apraglutide
1295353-98-8
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd |
-
- Apraglutide
1295353-98-8
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
