Isoflupredone Acetate
- CAS No.
- 338-98-7
- Chemical Name:
- Isoflupredone Acetate
- Synonyms
- predef;U-6013;biorinil;NSC 12600;NSC 37977;Predef R 2X;IsoflupredineAcetate;21-Acetoxy-9-fluoro-;Isoflupredone acetate;Nintedanib Impurity 156
- CBNumber:
- CB9500538
- Molecular Formula:
- C23H29FO6
- Molecular Weight:
- 420.47
- MDL Number:
- MFCD00468096
- MOL File:
- 338-98-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| IsoflupredoneAcetate | I816610 | 500mg | $790 |
| ISOFLUPREDONE ACETATE 95.00% | API0010029 | 1G | $1871.1 |
| ISOFLUPREDONE ACETATE 95.00% | API0010029 | 100MG | $739.2 |
| More product size | |||
| Melting point | 244-246° (dec) |
|---|---|
| alpha | D23 +108° (c = 0.735 in dioxane) |
| Boiling point | 576.5±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly) |
| pka | 12.05±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChIKey | ZOCUOMKMBMEYQV-BZIJPSHGNA-N |
| SMILES | [C@@]12([H])CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@]1(C)[C@@](CC[C@@]21[H])(O)C(=O)COC(=O)C |&1:0,10,12,14,17,19,22,r| |
| FDA UNII | 55P9TUL75S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
| HS Code | 2937220000 |
Isoflupredone Acetate price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | I816610 | IsoflupredoneAcetate | 338-98-7 | 500mg | $790 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010029 | ISOFLUPREDONE ACETATE 95.00% | 338-98-7 | 1G | $1871.1 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0010029 | ISOFLUPREDONE ACETATE 95.00% | 338-98-7 | 100MG | $739.2 | 2021-12-16 | Buy |
Isoflupredone Acetate Chemical Properties,Uses,Production
Uses
Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.
Definition
ChEBI: 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate is a corticosteroid hormone.
Veterinary Drugs and Treatments
Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids
can be used for its antiinflammatory or immunosuppressive
effects. Labeled indications for isoflupredone include: adjunctive
treatment of bovine ketosis, alleviating pain and lameness
associated with musculoskeletal conditions, acute hypersensitivity
reactions, adjunctive treatment of overwhelming infections with
severe toxicity, shock, supportive therapy in the treatment of stress
conditions (e.g., surgery), dystocia, retained placenta, inflammatory
ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce
inflammation associated with recurrent airway obstruction (RAO,
“heaves”, COPD).
While the drug could be used in small animals, it is recommended
to use other glucocorticoid agents instead, where there has been
more experience and other approved products for dogs and cats are
available.
in vivo
Isoflupredone acetate (0.05 mg/kg; i.m.; on days 2 and 4 after the challenge) prevents dry-matter intake and average daily gain reductions, and leads to faster Mannheimia haemolytica-infected clinical improvement when co-treated with Oxytetracycline.html" class="link-product" target="_blank">Oxytetracycline (HY-B0275)[2].
| Animal Model: | 96 weanling heifers (Bronchopneumonia was induced by intrabronchial infusion of Mannheimia haemolytica)[2] |
| Dosage: | 0.05 mg/kg |
| Administration: | i.m.; on days 2 and 4 after the challenge |
| Result: | Infection caused a reduction in dry-matter intake and average daily gain (ADG) in heifers. Prevented these reductions and resulted in faster clinical improvement when co-treated with Oxytetracycline (HY-B0275). |
Toxics Screening Level
The ITSL for Isoflupredone Acetate is 0.01 μg/m3 based on annual averaging.
Isoflupredone Acetate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 | sean.lv@synzest.com | China | 323 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 19282 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15080 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
View Lastest Price from Isoflupredone Acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-26 | Isoflupredone Acetate
338-98-7
|
US $32.00-107.00 / mg | 99.43% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-11-18 | Isoflupredone Acetate USP/EP/BP
338-98-7
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-09-25 | Isoflupredone Acetate
338-98-7
|
US $32.00-1.30 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-
- Isoflupredone Acetate
338-98-7
- US $32.00-107.00 / mg
- 99.43%
- TargetMol Chemicals Inc.
-
- Isoflupredone Acetate USP/EP/BP
338-98-7
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Isoflupredone Acetate
338-98-7
- US $32.00-1.30 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
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