EZH2 antibody
- CAS No.
- Chemical Name:
- EZH2 antibody
- Synonyms
- EZH2 antibody
- CBNumber:
- CB95626237
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
EZH2 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb734197 | EZH2 Antibody | 50μl | $260 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb734197 | EZH2 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb734196 | EZH2 Antibody | 50μl | $260 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb734196 | EZH2 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb2657671 | EZH2 Antibody | 10μl | $250 | 2026-05-06 | Buy |
EZH2 antibody Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human;Mouse;Rat;Pig
Background
The polycomb group proteins are involved in maintaining the silenced state of several developmentally regulated genes and contribute to the maintenance of cell identity, cell cycle regulation, and oncogenesis. Enhancer of zeste homolog 2, a member of this large protein family, contains four conserved regions including domain I, domain II, and a cysteine-rich amino acid stretch that precedes the carboxy-terminal SET domain. The SET domain has been linked with histone methyltransferase activity. Moreover, mammalian Ezh2 is a member of a histone deacetylase complex that functions in gene silencing, acting at the level of chromatin structure. Ezh2 complexes methylate histone H3 at Lys9 and 27 in vitro, which is thought to be involved in targeting transcriptional regulators to specific loci. Ezh2 is deregulated in various tumor types, and its role, both as a primary effector and as a mediator of tumorigenesis, has become a subject of increased interest.
References
[1] Sellers, W.R. and Loda, M. (2002) Cancer Cell 2, 349-50.
[2] Visser, H.P. et al. (2001) Br J Haematol 112, 950-8.
[3] Chen, H. et al. (1996) Genomics 38, 30-7.
[4] Tonini, T. et al. (2004) Oncogene 23, 4930-7.
[5] Müller, J. et al. (2002) Cell 111, 197-208.
[6] Kleer, C.G. et al. (2003) Proc Natl Acad Sci U S A 100, 11606-11.
EZH2 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
EZH2 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Universal Biotech Co.,Ltd | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
