LASP1 antibody
- CAS No.
- Chemical Name:
- LASP1 antibody
- Synonyms
- LASP1 Antibod;LASP1 antibody
- CBNumber:
- CB95650724
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| LASP1 Antibody | orb379936 | 100μl | $360 |
| LASP1 antibody Affinity purified by Protein A | orb184836 | 100μg | $421.6 |
| LASP1 antibody Affinity purified by Protein A | orb184836 | 200μg | $673.2 |
LASP1 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb379936 | LASP1 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb184836 | LASP1 antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb184836 | LASP1 antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
LASP1 antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human
Background
LASP1 is a cytoskeletal scaffold protein belonging to the LIM protein subfamily. LASP1 consists of an N-terminal LIM domain, followed by two nebulin repeats, and a C-terminal SH3 domain. The nebulin repeats interact with actin, while the SH3 domain interacts with palladin, suggesting LASP1 functions as an actin-binding protein, possibly in cytoskeletal organization. LASP1 has been shown to localize to focal adhesions, lamellipodia, and membrane ruffles and might be involved in membrane migration. Overexpression of LASP1 has been associated with metastatic cancers, such as breast and ovarian cancer. In these cases, membrane, cytoplasmic, and nuclear localization of LASP1 in the tumor cell has been reported, suggesting LASP1 involvement in membrane and nuclear signaling.
References
[1] Tomasetto, C. et al. (1995) FEBS Lett 373, 245-9.
[2] Grunewald, T.G. and Butt, E. (2008) Mol Cancer 7, 31.
[3] Schreiber, V. et al. (1998) Mol Med 4, 675-87.
[4] Chew, C.S. et al. (2002) J Cell Sci 115, 4787-99.
[5] Rachlin, A.S. and Otey, C.A. (2006) J Cell Sci 119, 995-1004.
[6] Chew, C.S. et al. (2000) J Cell Sci 113 ( Pt 11), 2035-45.
[7] Lin, Y.H. et al. (2004) J Cell Biol 165, 421-32.
[8] Grunewald, T.G. et al. (2007) Br J Cancer 96, 296-305.
[9] Frietsch, J.J. et al. (2010) Br J Cancer 102, 1645-1653.
[10] Traenka, C. et al. (2010) Cancer Res 70, 8003-8014.
LASP1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
LASP1 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89667 | 60 |
| Nanjing Anyan Biological Technology Co., Ltd. | 025-52151215 13915956535 13915956535 | 570945402@qq.com | China | 9733 | 58 |
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Novus Biologicals | -- | orders@novusbio.com | China | 6433 | 58 |
| CUSABIO TECHNOLOGY LLC | -- | cusabio@163.com | China | 6066 | 58 |
| GeneTex, Inc. | -- | international@genetex.com | China | 6092 | 58 |
| NSJ Bioreagents | -- | NSJBioname@qq.com | China | 6941 | 58 |
| Enzo Biochem Inc | -- | Enzoname@qq.com | China | 6173 | 58 |
| Biosynth Ltd | -- | sales@biosynth.com | China | 6218 | 58 |
| Cell Signaling Technology Inc | -- | info@cellsignal.cn | China | 6725 | 58 |
