SKP1 antibody
- CAS No.
- Chemical Name:
- SKP1 antibody
- Synonyms
- SKP1 antibody;Mouse Monoclonal SKP1 Antibody
- CBNumber:
- CB95696122
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
SKP1 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb622383 | Skp1 Antibody | 50μl | $400 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb622383 | Skp1 Antibody | 100μl | $540 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb192631 | SKP1 Antibody | 50μl | $350 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb192631 | SKP1 Antibody | 100μl | $480 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb2559 | SKP1 antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy |
SKP1 antibody Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human;Mouse;Rat
Background
Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2 and then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue. Combinatorial interactions of different E2 and E3 proteins result in substrate specificity. Recent data suggests that activated E2 associates transiently with E3, and the dissociation is a critical step for ubiquitination. S phase kinase-associated protein 1 is a critical scaffold protein of the Skp1/CUL1/F-box E3 ubiquitin ligase protein complex. Various F-box proteins mediate an interaction with Skp1, via their defining and conserved domain of 40 amino acids, and with substrates to be ubiquitinated.
References
[1] Ciechanover, A. (1998) EMBO J. 17, 7151-60.
[2] Hochstrasser, M. (2000) Nat. Cell Biol. 2, E153-7.
[3] Hochstrasser, M. (2000) Science 289, 563-4.
[4] DeSalle, L.M. and Pagano, M. (2001) FEBS Lett. 490, 179-89.
[5] Deffenbaugh, A.E. et al. (2003) Cell 114, 611-22.
SKP1 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
SKP1 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 027-19371278702 18008634902 | 19384116026@163.com | China | 3008 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
| Hubei Serenity BioSolutions Co., Ltd. | 58 |
