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2,3,5-Triphenyltetrazolium chloride

2,3,5-Triphenyltetrazolium chloride Structure
2,3,5-Triphenyltetrazolium chloride structure
CAS No.
298-96-4
Chemical Name:
2,3,5-Triphenyltetrazolium chloride
Synonyms
TTC;RT;TTZ;TETRAZOLIUM SALT;TRIPHENYLTETRAZOLIUM CHLORIDE;TETRAZOLIUM CHLORIDE;TTL;red tetazolium;2,3,5-TRIPHENYL-2H-TETRAZOLIUM CHLORIDE;LGMD2K
CBNumber:
CB9666209
Molecular Formula:
C19H15ClN4
Molecular Weight:
334.8
MDL Number:
MFCD00011963
MOL File:
298-96-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 12:01:10
Product description Number Pack Size Price
2,3,5-Triphenyltetrazolium chloride ≥98.0% (HPLC) T8877 5g $65.5
2,3,5-Triphenyltetrazolium chloride for microbiology 1.08380 10g $72.3
2,3,5-Triphenyl-tetrazolium chloride solution suitable for microbiology 17779 10amp $302
2,3,5-Triphenyltetrazolium chloride for microbiology 1.08380 100g $692
2,3,5-Triphenyl-2H-Tetrazolium Chloride TX1510 25g $281
More product size
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2,3,5-Triphenyltetrazolium chloride Properties

Melting point 250 °C(lit.)
Boiling point 490.96°C (rough estimate)
bulk density 230kg/m3
Density 1.1704 (rough estimate)
refractive index 1.6110 (estimate)
storage temp. 2-8°C
solubility H2O: may be clear to slightly hazy
form powder
color faint yellow
PH 3.7 (20°C, 10g/L in H2O)
Water Solubility Soluble in water, ethanol and acetone. Insoluble in ether.
λmax 247 nm
Sensitive Light Sensitive & Hygroscopic
Merck 14,9744
BRN 3923356
Stability Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents.
Biological Applications Algae viability assay; microbial growth assays; transketolase activity screening assays; detecting bacteria,g-hydroxybutyric acid (GHB),microorganisms,myocardial infarction; measuring dehydrogenase activity; treating cancer
Major Application diagnostic assay manufacturing
hematology
histology
InChI 1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
InChIKey PKDBCJSWQUOKDO-UHFFFAOYSA-M
SMILES [Cl-].c1ccc(cc1)-c2nn(-c3ccccc3)[n+](n2)-c4ccccc4
CAS DataBase Reference 298-96-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII D25727K0RB
EPA Substance Registry System 2,3,5-Triphenyltetrazolium chloride (298-96-4)
UNSPSC Code 41171614
NACRES NA.85

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H228-H315-H319
Precautionary statements  P210-P240-P241-P264-P302+P352-P305+P351+P338
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36
WGK Germany  3
RTECS  XF8100000
F  3-8-10
TSCA  TSCA listed
HS Code  29339900
Storage Class 4.1B - Flammable solid hazardous materials
Hazard Classifications Eye Irrit. 2
Flam. Sol. 1
Skin Irrit. 2
Toxicity LD50 intravenous in mouse: 5600ug/kg
NFPA 704
1
2 0

2,3,5-Triphenyltetrazolium chloride price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T8877 2,3,5-Triphenyltetrazolium chloride ≥98.0% (HPLC) 298-96-4 5g $65.5 2026-04-30 Buy
Sigma-Aldrich 1.08380 2,3,5-Triphenyltetrazolium chloride for microbiology 298-96-4 10g $72.3 2026-04-30 Buy
Sigma-Aldrich 17779 2,3,5-Triphenyl-tetrazolium chloride solution suitable for microbiology 298-96-4 10amp $302 2026-04-30 Buy
Sigma-Aldrich 1.08380 2,3,5-Triphenyltetrazolium chloride for microbiology 298-96-4 100g $692 2026-04-30 Buy
Sigma-Aldrich TX1510 2,3,5-Triphenyl-2H-Tetrazolium Chloride 298-96-4 25g $281 2022-05-15 Buy
Product number Packaging Price Buy
T8877 5g $65.5 Buy
1.08380 10g $72.3 Buy
17779 10amp $302 Buy
1.08380 100g $692 Buy
TX1510 25g $281 Buy

2,3,5-Triphenyltetrazolium chloride Chemical Properties,Uses,Production

Chemical Properties

white powder

Uses

2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies.

Uses

2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia

Uses

In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases.

Definition

ChEBI: An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion.

General Description

2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.

Synthesis

Triphenylformazan

531-52-2

2,3,5-Triphenyltetrazolium chloride

298-96-4

E. The 2,3,5-triphenylformamidine (IV-1) solid obtained in Step D was mixed with 300 mL of dichloromethane and 300 mL of water. After the solid was completely dissolved, N-chlorosuccinimide (0.11 mol, 14.7 g) was added and the reaction was carried out with stirring at 0 °C for 5 h. F. The reaction mixture from Step E was allowed to partition and the upper aqueous phase was separated. The organic phase was distilled under reduced pressure to remove the solvent to give the crude product 2,3,5-triphenyltetrazole (V-1). The crude product was purified by recrystallization with chloroform to give 30.2 g of pure product (yield: 90%).

Purification Methods

Crystallise TTZ from EtOH or CHCl3, and dry it at 105o. [Beilstein 26 H 363, 26 II 216, 26 III/IV 1774.]

References

[1] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983, vol. 22, # 8, p. 771 - 775
[2] J. Appl. Chem. USSR (Engl. Transl.), 1983, vol. 56, # 3, p. 617 - 621
[3] Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1983, vol. 56, # 3, p. 649 - 653
[4] Patent: CN108440433, 2018, A. Location in patent: Paragraph 0057; 0058; 0059; 0064; 0065
[5] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981, vol. 20, # 5, p. 404 - 406

2,3,5-Triphenyltetrazolium chloride synthesis

531-52-2
298-96-4
Synthesis of 2,3,5-Triphenyltetrazolium chloride from Triphenylformazan

2,3,5-Triphenyltetrazolium chloride Preparation Products And Raw materials

Raw materials

Sodium acetate Sodium hypochlorite Sodium nitrite Benzaldehyde Aniline
Hydrochloric acid Acetic acid Sodium hydroxide Phenylhydrazine Triphenylformazan

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Preparation Products

2,3,5-Triphenyltetrazolium chloride Suppliers

Global( 752)Suppliers
Supplier Tel Email Country ProdList Advantage
Hainan Fubai Trading Co., LTD 		+undefined852-57423927 13313004729@163.com China 103 58
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Longbang Technology Co., LTD 		+86-18633929156 admin@hblongbang.com China 972 58
HebeiShuoshengImportandExportco.,Ltd 		+86-18532138899 L18532138899@163.com China 939 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16513 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +8618949832763 info@tnjchem.com China 2988 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
Supplier Advantage
Hainan Fubai Trading Co., LTD 		58
Fuxin Pharmaceutical
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Longbang Technology Co., LTD 		58
HebeiShuoshengImportandExportco.,Ltd 		58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Hefei TNJ Chemical Industry Co.,Ltd. 		55
Shanghai Zheyan Biotech Co., Ltd. 		58

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View Lastest Price from 2,3,5-Triphenyltetrazolium chloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3,5-Triphenyltetrazolium chloride pictures 2026-05-06 2,3,5-Triphenyltetrazolium chloride
298-96-4
 US $0.00 / KG 1KG 99% 3500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Tetrazolium Red pictures 2026-04-23 Tetrazolium Red
298-96-4
 US $29.00 / mL 99.82% 10g TargetMol Chemicals Inc.
2,3,5-Triphenyltetrazolium chloride pictures 2026-04-17 2,3,5-Triphenyltetrazolium chloride
298-96-4
 US $2.20-8.80 / KG 1KG 99% g-kg-tons ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2,3,5-Triphenyltetrazolium chloride Spectrum

2,3,5-Triphenyltetrazolium chloride(298-96-4)1HNMR2,3,5-Triphenyltetrazolium chloride(298-96-4)13CNMR2,3,5-Triphenyltetrazolium chloride(298-96-4)IR12,3,5-Triphenyltetrazolium chloride(298-96-4)IR22,3,5-Triphenyltetrazolium chloride(298-96-4)Raman

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2,3,5-TriphenyltetrazoliuM chloride SynonyMs 2,3,5-Triphenyl-2H-tetrazoliuM chloride TTC,TTZ,Tetrazolium Red FLJ37239 LGMD2K 10 MG ABTS TABLETS BCIP P-TOLUIDINE SALT ULTRA PURE GRADE TSA PENASE CONTACT 55MM TRIPLE-WRAP red tetazolium RARECHEM AH BS 0067 TETRAZOLE RED TETRAZOLIUM RED TETRAZOLIUM RED CHLORIDE 2-MERCAPTO-3-METHYL-5-OXO-6-HYDROXY-1,2,4-TRIAZINE 2-METHYL-3-THIOXOHEXAHYDRO-1,2,4-TRIAZINE-5,6-DIONE 2H-TETRAZOLIUM, 2,3,5-TRIPHENYL-, CHLORIDE 2,3,5-TRIPHENYL-2H-TETRAZOLIUM CHLORIDE 2,3,5-TRIPHENYLTETRAZOLIUM CHLORIDE 2,5-DIHYDRO-6-HYDROXY-3-MERCAPTO-2-METHYL-5-OXO-1,2,4-TRIAZINE Red tetrazoline LABOTEST-BB LT00086927 2,3,5-Triphenyl-2H-tetrazololium chloride Tertrazolium red TTC SOLUTION, PGE. 10 VIALS WITH 10 ML* 2,3,5-Triphenyl-2H-TetrazoliumChloride(Ttc) 3,5-Triphenyl-2H-TetrazoliumChloride TetrazoliumSaltGr(Ttc) TetrazoliumSaltGr-(Ttc,2,3,5-TriphenylTetrazoliumChloride) TetrazoliumSaltGr TertazoliumRed Ttc(2,3,5-Triphenyl-2H-TetrazoliumChloride) Triphenyltetrazolium 2,3,5-triphenyl-tetrazolium chloride solution tetrzoliumchloride urocheck uroscreen vitastain 2,3,5-Triphenyltetrazolium chloride BioChemika, >99.0% (AT) 2,3,5-TRIPHENYLTETRAZOLIUM CHLORIDE (TTC) Tetrazolium Red, TPTZ, TTZ TRIPHENYLTETRAZOLIUMCHLORIDE,REAGENT TTC(TTZ) TRIPHENYLTETRAZOLIUM CHLORIDEANALYTICAL GRADE 2,3,5-Triphenyl-tetrazolium chloride solution,TTC 2,3,5-Triphenyltetrazolium chloride,TPTZ, TTZ, Tetrazolium Red 2,3,5-Triphenyltetrazolium chloride p.a. 2,3,5-Triphenyltetra Tetrazolium Red, TTC, TTZ 1,3,5-Triphenyl-2H-tetrazolium chloride 1,3,5-Triphenyltetrazolium chloride 2,3,5-Triphenyl-2H-tetrazolium chloride,98% 2,3,5-TRIPHENYLTETRAZOLIUM CHLORIDE extrapure Tetrazole Red Tetrazolium Red TTC TTC/TPTZ/TTZ/RT TTL 2,3,5-Triphenyl-,chloride 2,3,5-triphenyl-2h-tetrazoliuchloride 2,3,5-triphenyl-2h-tetrazolium Ttc (dye)