4-Fluorophenol
- CAS No.
- 371-41-5
- Chemical Name:
- 4-Fluorophenol
- Synonyms
- Fluorophenol;P-FLUOROPHENOL;FPO;p-Fluorphenol;p-Fluorohenol;4-Fluorphenol;4-FLUOROPHENOL;P-flrorophenol;4-fluoro-pheno;p-fluoro-pheno
- CBNumber:
- CB9672628
- Molecular Formula:
- C6H5FO
- Molecular Weight:
- 112.1
- MDL Number:
- MFCD00002316
- MOL File:
- 371-41-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Fluorophenol 99% | F13207 | 25g | $50.2 |
| 4-Fluorophenol 99% | F13207 | 100g | $113 |
| 4-Fluorophenol >99.0%(GC) | F0160 | 25g | $31 |
| 4-Fluorophenol >99.0%(GC) | F0160 | 500g | $305 |
| p-Fluorophenol, 99% | 09-4090 | 25g | $52 |
| More product size | |||
| Melting point | 43-46 °C (lit.) |
|---|---|
| Boiling point | 185 °C (lit.) |
| Density | 1.22 |
| Flash point | 155 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | 80g/l |
| pka | 9.89(at 25℃) |
| form | Crystalline Solid |
| color | Yellow-beige to pink |
| PH | 5.4 (H2O, 20℃)(saturated aqueous solution) |
| Water Solubility | 50 g/L |
| BRN | 1362752 |
| Henry's Law Constant | 1.4×101 mol/(m3Pa) at 25℃, Abraham et al. (1994) |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| InChI | 1S/C6H5FO/c7-5-1-3-6(8)4-2-5/h1-4,8H |
| InChIKey | RHMPLDJJXGPMEX-UHFFFAOYSA-N |
| SMILES | Oc1ccc(F)cc1 |
| Dissociation constant | 0 at 27℃ |
| CAS DataBase Reference | 371-41-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | K6DT6TR5E5 |
| NIST Chemistry Reference | Phenol, 4-fluoro-(371-41-5) |
| EPA Substance Registry System | Phenol, 4-fluoro- (371-41-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,C,T,F+ | |||||||||
| Risk Statements | 20/21/22-36/37/38-52/53 | |||||||||
| Safety Statements | 26-37/39-61-36 | |||||||||
| RIDADR | UN 2928 6.1/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | SL4550000 | |||||||||
| F | 10-23 | |||||||||
| Hazard Note | Corrosive/Harmful | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29081000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Aquatic Chronic 3 Eye Irrit. 2 Skin Irrit. 2 |
|||||||||
| NFPA 704 |
|
4-Fluorophenol price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F13207 | 4-Fluorophenol 99% | 371-41-5 | 25g | $50.2 | 2026-03-19 | Buy |
| Sigma-Aldrich | F13207 | 4-Fluorophenol 99% | 371-41-5 | 100g | $113 | 2026-03-19 | Buy |
| TCI Chemical | F0160 | 4-Fluorophenol >99.0%(GC) | 371-41-5 | 25g | $31 | 2026-03-19 | Buy |
| TCI Chemical | F0160 | 4-Fluorophenol >99.0%(GC) | 371-41-5 | 500g | $305 | 2026-03-19 | Buy |
| Strem Chemicals | 09-4090 | p-Fluorophenol, 99% | 371-41-5 | 25g | $52 | 2024-03-01 | Buy |
4-Fluorophenol Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Fluorophenol is a fluorinated phenolic compound with various applications as a starting reagent for synthesizing pharmaceuticals. It is a widely used intermediate in the industrial production of several drugs, including cisapride and Sabeluzole by Janssen, Sorbinil by Pfizer, and Progabide by Synthelabo.
Definition
ChEBI: 4-fluorophenol is a fluorophenol that is phenol in which the hydrogen para- to the hydroxy group has been replaced by a fluorine. It is a fluorophenol and a member of monofluorobenzenes. It is used as an intermediate in the production of liquid crystals.
Preparation
Acetyl hypofluorite also will fluoro-demetallate benzene derivatives, for example mercury derivatives of phenol gave 4-fluorophenol.
Synthesis Reference(s)
Tetrahedron, 52, p. 23, 1996 DOI: 10.1016/0040-4020(95)00867-8
Hazard
Irritant.
4-Fluorophenol Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13815 | 58 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
View Lastest Price from 4-Fluorophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | 4-Fluorophenol
371-41-5
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-09-25 | 4-Fluorophenol
371-40-5
|
US $9.00-0.90 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
![]() |
2025-09-25 | 4-Fluorophenol
371-41-5
|
US $9.00-0.90 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
-

- 4-Fluorophenol
371-41-5
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-

- 4-Fluorophenol
371-40-5
- US $9.00-0.90 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 4-Fluorophenol
371-41-5
- US $9.00-0.90 / KG
- 99%
- Henan Fengda Chemical Co., Ltd







