3-Hydroxy-2-nitrobenzoic acid
- CAS No.
- 602-00-6
- Chemical Name:
- 3-Hydroxy-2-nitrobenzoic acid
- Synonyms
- Benzoic acid, hydroxynitro-;3-HYDROXY-2-NITROBENZOIC ACID;2-NITRO-3-HYDROXYBENZOIC ACID;3-Hydroxy-2-nitrobenzoicAcid>Benzoic acid, 3-hydroxy-2-nitro-;3-HYDROXY-2-NITROBENZOIC ACID, 98+%
- CBNumber:
- CB9676787
- Molecular Formula:
- C7H5NO5
- Molecular Weight:
- 183.12
- MDL Number:
- MFCD00017003
- MOL File:
- 602-00-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Hydroxy-2-nitrobenzoic Acid >98.0%(GC)(T) | H1324 | 1g | $58 |
| 3-Hydroxy-2-nitrobenzoic Acid >98.0%(GC)(T) | H1324 | 5g | $270 |
| 3-Hydroxy-2-nitrobenzoic Acid | TRC-H950898-5G | 5g | $415 |
| 3-Hydroxy-2-nitrobenzoic Acid | TRC-H950898-500MG | 500mg | $72 |
| 3-Hydroxy-2-nitrobenzoic Acid | TRC-H950898-1G | 1g | $123 |
| More product size | |||
| Melting point | 179-181°C |
|---|---|
| Boiling point | 363°C |
| Density | 1.631 |
| Flash point | 167°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.07±0.10(Predicted) |
| color | Light Beige to Light Brown |
| BRN | 2372248 |
| InChI | InChI=1S/C7H5NO5/c9-5-3-1-2-4(7(10)11)6(5)8(12)13/h1-3,9H,(H,10,11) |
| InChIKey | KPDBKQKRDJPBRM-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(O)=C1[N+]([O-])=O |
| CAS DataBase Reference | 602-00-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-37 | |||||||||
| HS Code | 29163990 | |||||||||
| NFPA 704 |
|
3-Hydroxy-2-nitrobenzoic acid price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H1324 | 3-Hydroxy-2-nitrobenzoic Acid >98.0%(GC)(T) | 602-00-6 | 1g | $58 | 2026-04-30 | Buy |
| TCI Chemical | H1324 | 3-Hydroxy-2-nitrobenzoic Acid >98.0%(GC)(T) | 602-00-6 | 5g | $270 | 2026-04-30 | Buy |
| TRC | TRC-H950898-5G | 3-Hydroxy-2-nitrobenzoic Acid | 602-00-6 | 5g | $415 | 2026-06-03 | Buy |
| TRC | TRC-H950898-500MG | 3-Hydroxy-2-nitrobenzoic Acid | 602-00-6 | 500mg | $72 | 2026-06-03 | Buy |
| TRC | TRC-H950898-1G | 3-Hydroxy-2-nitrobenzoic Acid | 602-00-6 | 1g | $123 | 2026-06-03 | Buy |
3-Hydroxy-2-nitrobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
3-Hydroxy-2-nitrobenzoic Acid (cas# 602-00-6) is a compound useful in organic synthesis.
Synthesis
4771-47-5
602-00-6
Step 1: 3-Chloro-2-nitrobenzoic acid (30 g, 0.148 mol) was dissolved in aqueous potassium hydroxide solution (240 g, 4.277 mol in 300 mL H2O) and stirred at room temperature until completely dissolved. Subsequently, the reaction mixture was heated to 110°C and kept for 12 hours for the reaction. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with water and acidified with concentrated hydrochloric acid to pH 2. The acidified mixture was cooled at 0°C and subsequently extracted with ethyl acetate (2 x 500 mL). The organic layers were combined, washed with brine solution, dried over anhydrous sodium sulfate and filtered. The filtrate was evaporated under reduced pressure to give 3-hydroxy-2-nitrobenzoic acid (27 g, 99% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 13.8 (brs, 1H), 11.21 (s, 1H), 7.47 (t, J = 8.0 Hz, 1H), 7.39 (dd, J' = 8.0 Hz, J'' = 1.6 Hz, 1H), 7.30 (dd, J'' = 7.6 Hz, J'' = 0.8 Hz. 1H); ESI-MS: calculated mass: 183.02; observed mass: 182.10 [M-H]-.
References
[1] Patent: WO2007/125405, 2007, A2. Location in patent: Page/Page column 24; 72
[2] Patent: WO2014/169167, 2014, A1. Location in patent: Page/Page column 61
[3] Dalton Transactions, 2012, vol. 41, # 31, p. 9272 - 9275
[4] Patent: US2014/87992, 2014, A1. Location in patent: Paragraph 0312-0313
[5] Patent: US2009/197863, 2009, A1. Location in patent: Page/Page column 55
3-Hydroxy-2-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3970 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 3-Hydroxy-2-nitrobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 3-Hydroxy-2-nitrobenzoic acid
602-00-6
|
$3.00 | 1KG | 98% | 200KG | Career Henan Chemical Co |
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- 3-Hydroxy-2-nitrobenzoic acid
602-00-6
- $3.00
- 98%
- Career Henan Chemical Co
