ChemicalBook >> CAS DataBase List >>Pentafluoro-1-propanol
Pentafluoro-1-propanol
- CAS No.
- 422-05-9
- Chemical Name:
- Pentafluoro-1-propanol
- Synonyms
- PFPOH;2,2,3,3,3-PENTAFLUOROPROPAN-1-OL;2,2,3,3,3-PENTAFLUORO-1-PROPANOL;PENTAFLUOROPROPANOL;C2F5CH2OH;2,2,3,3,3-PENTAFLUOROPROPANOL;PENTAFLUORO-1-PROPANOL;1,1H-perfluoropropanol;1H,1H-Perfluoropropanol;Pentafluoropropylalcohol
- CBNumber:
- CB9689963
- Molecular Formula:
- C3H3F5O
- Molecular Weight:
- 150.05
- MDL Number:
- MFCD00004673
- MOL File:
- 422-05-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:43:36
| Boiling point | 80 °C748 mm Hg(lit.) |
|---|---|
| Density | 1.505 g/mL at 25 °C(lit.) |
| vapor pressure | 62.055-324.857hPa at 24.93-54.78℃ |
| refractive index |
n |
| Flash point | 80-81°C |
| storage temp. | Flammables area |
| form | Powder, Crystals and/or Chunks |
| pka | 12.45±0.10(Predicted) |
| Specific Gravity | 1.509 |
| color | White to off-white to light yellow |
| Water Solubility | Soluble in water.21.9 g/L at 25°C |
| BRN | 1743133 |
| Henry's Law Constant | 1.4×10-1 mol/(m3Pa) at 25℃, Burkholder et al. (2019) |
| InChI | 1S/C3H3F5O/c4-2(5,1-9)3(6,7)8/h9H,1H2 |
| InChIKey | PSQZJKGXDGNDFP-UHFFFAOYSA-N |
| SMILES | OCC(F)(F)C(F)(F)F |
| LogP | 1.23 |
| CAS DataBase Reference | 422-05-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | EPJ1S961SN |
| NIST Chemistry Reference | 2,2,3,3,3-Pentafluoro-1-propanol(422-05-9) |
| EPA Substance Registry System | 1-Propanol, 2,2,3,3,3-pentafluoro- (422-05-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P280a-P304+P340-P405-P501a-P261-P305+P351+P338 | |||||||||
| target organs | Liver | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-20-10 | |||||||||
| Safety Statements | 26-36-36/37/39-16 | |||||||||
| RIDADR | 1987 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UB8800000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29055900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral STOT RE 2 Inhalation |
|||||||||
| Toxicity | LDLo orl-rat: 2250 mg/kg JOCMA7 4,262,62 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Pentafluoro-1-propanol price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 257478 | 2,2,3,3,3-Pentafluoro-1-propanol 97% | 422-05-9 | 5g | $45.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 257478 | 2,2,3,3,3-Pentafluoro-1-propanol 97% | 422-05-9 | 25g | $143 | 2026-04-30 | Buy |
| TCI Chemical | P0845 | 2,2,3,3,3-Pentafluoro-1-propanol >98.0%(GC) | 422-05-9 | 25g | $102 | 2026-04-30 | Buy |
| Apolloscientific | PC5706 | 2,2,3,3,3-Pentafluoropropan-1-ol 98% | 422-05-9 | 25g | $25 | 2026-06-04 | Buy |
| Apolloscientific | PC5706 | 2,2,3,3,3-Pentafluoropropan-1-ol 98% | 422-05-9 | 100g | $66 | 2026-06-04 | Buy |
Pentafluoro-1-propanol Chemical Properties, Uses, Production
Chemical Properties
clear colorless to slightly yellow liquid
Uses
2,2,3,3,3-Pentafluoro-1-Propanol is a useful reagent for the preparation of (oxoindolinyl)ethers/benzoates via photochemical O-H functionalization reactions of cyclic diazoamides.
Uses
2,2,3,3,3-Pentafluoro-1-propanol has been used:
- as derivatization reagent in detection of unlabeled and 15N2 -labeled L-tryptophan, L-kynurenine, serotonin and quinolinic acid in human and rat plasma by GC-MS
- as derivatization reagent in simultaneous analysis of cocaine, cocaethylene and their possible metabolic and pyrolytic products in blood, urine and muscle by GC-MS
- preparation of trifluoromethyl ynamines which, in turn, converted aldehydes to α-trifluoromethyl-α,β-unsaturated amides
- to generate fluorinated α-keto ethers with alkenes and has wide applications in the expanding fluorous research area
General Description
2,2,3,3,3-Pentafluoro-1-propanol is an alternative cleaning agent for chlorofluorocarbon.
reaction suitability
reagent type: derivatization reagent
reaction type: Acylations
Safety Profile
Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Fí.
Purification Methods
Shake the alcohol with alumina for 24hours, dry with anhydrous K2CO3, and distil it, collect the middle fraction (b 80-81o) and redistil it. [Beilstein 1 IV 1438.]
Pentafluoro-1-propanol Preparation Products And Raw materials
Global Suppliers ( 258)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
View Latest Price from Pentafluoro-1-propanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | Pentafluoro-1-propanol
422-05-9
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2019-07-06 | 2,2,3,3,3-Pentafluoro-1-Propanol
422-05-9
|
$250.00 | 2KG | 98% | 500kg per month | Career Henan Chemical Co |
-
- Pentafluoro-1-propanol
422-05-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2,2,3,3,3-Pentafluoro-1-Propanol
422-05-9
- $250.00
- 98%
- Career Henan Chemical Co
422-05-9 (Pentafluoro-1-propanol) Related Search:
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2,2,3,3,3-Pentafluoro-1-propanol,97%
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2,2,3,3,3-pentafluoro-1-propano
propanol,2,2,3,3,3-pentafluoro-
Pentafluoropropionic alcohol
1H,1H-PENTAFLUORO-1-PROPANOL
1H,1H-PENTAFLUOROPROPANOL
1H,1H-PENTAFLUOROPROPANOL-1
2,2,3,3,3-Pentafluoro-1-propanol>
2,2,3,3,3-Pentafluoropropan-1-ol in methanol
1H,1H-Perfluoropropanol
1H,1H-Perfluoropropanol in Methanol
2,2,3,3,3-Pentafluoro-1-propanol, 98%
2,2,3,3,3-Pentafluoropropan-1-ol, 100 μg/mL PT Methanol
2,2,3,3,3-PENTAFLUORO-1-PROPANOL
2,2,3,3,3-PENTAFLUOROPROPANOL
2,2,3,3,3-PENTAFLUOROPROPAN-1-OL
C2F5CH2OH
PENTAFLUOROPROPANOL
PFPOH
422-05-9
CF3CF2CH2OH
C3H3OF5
Organic Building Blocks
Oxygen Compounds
C2 to C6
Building Blocks
Alkylation
Alcohols
ALCOHOL
Acylation Reagent
