ChemicalBook >> CAS DataBase List >>(+/-)4-HDOHE

(+/-)4-HDOHE

CAS No.
90906-40-4
Chemical Name:
(+/-)4-HDOHE
Synonyms
(±)4-HDHA;(±)4-HDHA;(±)4-HDoHE;(+/-)4-HDOHE;(+/-)4-HDOHE;IFRKCNPQVIJFAQ-PQVBWYSWSA-N;4-HYDROXY DOCOSAHEXAENOIC ACID;4-Hydroxy-5(E),7(Z),10(Z),13(Z),16(Z),19(Z)-DHA;(+/-)4-HYDROXY-5E,7Z,10Z,13Z,16Z,19Z-DOCOSAHEXAENOIC ACID;5,7,10,13,16,19-Docosahexaenoic acid, 4-hydroxy-, (5E,7Z,10Z,13Z,16Z,19Z)-
CBNumber:
CB9700248
Molecular Formula:
C22H32O3
Molecular Weight:
344.49
MDL Number:
MFCD02262235
MOL File:
90906-40-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

(+/-)4-HDOHE Properties

Boiling point 502.3±50.0 °C(Predicted)
Density 0.995±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
pka 4.57±0.10(Predicted)
form Liquid
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Danger
NFPA 704
3
0 0

(+/-)4-HDOHE price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 33200 (±)4-HDHA ≥95% 90906-40-4 25μg $85 2026-04-30 Buy
Cayman Chemical 33200 (±)4-HDHA ≥95% 90906-40-4 50μg $159 2026-04-30 Buy
Cayman Chemical 33200 (±)4-HDHA ≥95% 90906-40-4 100μg $301 2026-04-30 Buy
Biorbyt Ltd orb1985040 (±)4-HDHA 97.97% 90906-40-4 25μg(2.90mMx25μlinMeOH) $210 2026-05-06 Buy
Biorbyt Ltd orb1985040 (±)4-HDHA 97.97% 90906-40-4 50μg(2.90mMx50μlinMeOH) $340 2026-05-06 Buy
Product number Packaging Price Buy
33200 25μg $85 Buy
33200 50μg $159 Buy
33200 100μg $301 Buy
orb1985040 25μg(2.90mMx25μlinMeOH) $210 Buy
orb1985040 50μg(2.90mMx50μlinMeOH) $340 Buy

(+/-)4-HDOHE Chemical Properties, Uses, Production

Description

(±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells also produces 4-HDHA. However, the enzymatic product is most likely the S-isomer. (±)4-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

Uses

(±)4-HDHA (4-Hydroxy docosahexaenoic acid) is an autoxidation product of Docosahexaenoic acid (HY-B2167) (DHA). (±)4-HDHA is a PPARγ agonist, antidiabetic and anti-inflammatory agent[1][2].

IC 50

PPARγ

References

[1] Yamamoto K, et al. 4-Hydroxydocosahexaenoic acid, a potent peroxisome proliferator-activated receptor gamma agonist alleviates the symptoms of DSS-induced colitis. Biochem Biophys Res Commun. 2008 Mar 14;367(3):566-72. DOI:10.1016/j.bbrc.2007.12.188
[2] Richard Louis Dunbar, et al. Lymph-releasing compositions of fatty acids and uses thereof for lymphatic incorporation and systemic disease treatment. Patent. WO2023146984.

(+/-)4-HDOHE Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)4-HDOHE Suppliers

Global Suppliers ( 26)
Supplier Tel Email Country ProdList Advantage
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1978 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9170 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
amyjet 4006800868;027-59626688 18771149750 sales@amyjet.com China 2909 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29676 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58

View Latest Price from (+/-)4-HDOHE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(±)4-HDHA pictures 2026-07-27 (±)4-HDHA
90906-40-4
$238.00 97.97% 10g TargetMol Chemicals Inc.
  • (±)4-HDHA pictures
  • (±)4-HDHA
    90906-40-4
  • $238.00
  • 97.97%
  • TargetMol Chemicals Inc.

(+/-)4-HDOHE Spectrum

4-HYDROXY DOCOSAHEXAENOIC ACID (+/-)4-HDOHE (+/-)4-HYDROXY-5E,7Z,10Z,13Z,16Z,19Z-DOCOSAHEXAENOIC ACID (±)4-HDHA IFRKCNPQVIJFAQ-PQVBWYSWSA-N 5,7,10,13,16,19-Docosahexaenoic acid, 4-hydroxy-, (5E,7Z,10Z,13Z,16Z,19Z)- (±)4-HDHA 4-Hydroxy-5(E),7(Z),10(Z),13(Z),16(Z),19(Z)-DHA (±)4-HDoHE (+/-)4-HDOHE 90906-40-4