5-BROMO-6-METHOXYPYRIDIN-2-AMINE
- CAS No.
- 1211533-83-3
- Chemical Name:
- 5-BROMO-6-METHOXYPYRIDIN-2-AMINE
- Synonyms
- 5-BROMO-6-METHOXYPYRIDIN-2-AMINE;5-Bromo-6-methoxy-2-pyridinamine;2-Pyridinamine, 5-bromo-6-methoxy-;5-Bromo-6-methoxy-pyridin-2-ylamine
- CBNumber:
- CB9701977
- Molecular Formula:
- C6H7BrN2O
- Molecular Weight:
- 203.04
- MDL Number:
- MFCD08062947
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| 5-Bromo-6-methoxypyridin-2-amine | B679503 | 10mg | $45 |
| 2-AMINO-5-BROMO-6-METHOXYPYRIDINE 95.00% | HCH0354650 | 250MG | $297.15 |
| 5-BROMO-6-METHOXYPYRIDIN-2-AMINE 95% | SC-40701 | 1g | $390 |
| 5-Bromo-6-methoxypyridin-2-amine 97% | UT01317 | 5g | $435.58 |
| 5-bromo-6-methoxypyridin-2-amine 98% | CM131016 | 5g | $617 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
5-BROMO-6-METHOXYPYRIDIN-2-AMINE price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B679503 | 5-Bromo-6-methoxypyridin-2-amine | 1211533-83-3 | 10mg | $45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0354650 | 2-AMINO-5-BROMO-6-METHOXYPYRIDINE 95.00% | 1211533-83-3 | 250MG | $297.15 | 2021-12-16 | Buy |
| SynChem | SC-40701 | 5-BROMO-6-METHOXYPYRIDIN-2-AMINE 95% | 1211533-83-3 | 1g | $390 | 2021-12-16 | Buy |
| Acrotein | UT01317 | 5-Bromo-6-methoxypyridin-2-amine 97% | 1211533-83-3 | 5g | $435.58 | 2021-12-16 | Buy |
| Chemenu | CM131016 | 5-bromo-6-methoxypyridin-2-amine 98% | 1211533-83-3 | 5g | $617 | 2021-12-16 | Buy |
5-BROMO-6-METHOXYPYRIDIN-2-AMINE Chemical Properties,Uses,Production
Synthesis
67-56-1
89284-11-7
1211533-83-3
The general procedure for the synthesis of 2-amino-5-bromo-6-methoxypyridine from methanol and 5,6-dibromopyridin-2-amine was as follows: sodium metal (1.8 g, 78.2 mmol) was added in small portions to dry methanol (70 mL) at -20 °C. The resulting solution was stirred at 0 °C for 4 hours. Subsequently, the reaction mixture was transferred to a sealed tube, 5,6-dibromopyridin-2-amine (Example 7a, 10 g, 39.8 mmol) was added and heated at 120 °C for 24 hours. After completion of the reaction, the solvent was removed under reduced pressure and the residue was diluted with water. The aqueous phase was neutralized with 2 M HCl and then extracted with ethyl acetate (3 x 100 mL). The organic phases were combined, dried with magnesium sulfate, filtered and concentrated in vacuum. The residue was purified by fast column chromatography using a gradient elution with a hexane solution of 5% to 15% acetone to afford the target product 2-amino-5-bromo-6-methoxypyridine (6.6 g, 82% yield). The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 3.91 (s, 3H), 4.31 (br. s., 2H), 5.99 (d, 1H), 7.48 (d, 1H). esms m/z 202.8, 204.8 [M + H]+.
References
[1] Patent: US2012/122843, 2012, A1. Location in patent: Page/Page column 15
[2] Patent: WO2015/109109, 2015, A1. Location in patent: Paragraph 0711
[3] Patent: US2017/44182, 2017, A1. Location in patent: Paragraph 0983
5-BROMO-6-METHOXYPYRIDIN-2-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Honest Joy Holdings Limited | 0755-36694831 +8613717124449 | sale@feiyang.com.cn | China | 300 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9999 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Huadong Medicine (Xi'an)Bodyguard Pharmaceutical Co.,Ltd. | +86-029-86185165 +8618629664246 | guoyuan@eastchinapharm.com | China | 1615 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49958 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9951 | 58 |
