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15-Crown-5

15-Crown-5 structure

CAS No.: 33100-27-5

Chemical Name:: 15-Crown-5

Synonyms: crown ether;1,4,7,10,13-PENTAOXACYCLOPENTADECANE;15-Crown-6;15-Crown-5 98%;15-CROWN 5-ETHER;15-CROWN-5;15-ether-5;Crownethers;15-CROWN-5,99%;JACS-33100-27-5

CBNumber:: CB9707287

Molecular Formula:: C10H20O5

Molecular Weight:: 220.26

MDL Number:: MFCD00005110

MOL File:: 33100-27-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:49:22

Product description	Number	Pack Size	Price
15-Crown-5 98%	188832	1g	$25.8
15-Crown-5 98%	188832	5g	$70.3
15-Crown 5-Ether >97.0%(GC)	C0859	5mL	$52
15-Crown 5-Ether >97.0%(GC)	C0859	25mL	$136
15-Crown-5, 98% 98%	08-0300	2g	$40
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15-Crown-5 Properties

Melting point	-20°C(lit.)
Boiling point	93-96 °C/0.05 mmHg (lit.)
Density	1.113 g/mL at 20 °C (lit.)
vapor pressure	0.5-0.82Pa at 20-25℃
refractive index	n20/D 1.465(lit.)
Flash point	>230 °F
storage temp.	room temp
solubility	Miscible with organic solvents.
form	Liquid
color	Clear colorless to light yellow
Specific Gravity	1.109
Water Solubility	MISCIBLE
Sensitive	Hygroscopic
BRN	1618144
Stability	Stable. Incompatible with oxidizing agents, strong acids. Avoid exposure to water or moist air.
InChI	1S/C10H20O5/c1-2-12-5-6-14-9-10-15-8-7-13-4-3-11-1/h1-10H2
InChIKey	VFTFKUDGYRBSAL-UHFFFAOYSA-N
SMILES	O1CCOCCOCCOCCOCC1
LogP	-0.9 at 20℃ and pH7.7
Surface tension	68.5mN/m at 1g/L and 20℃
CAS DataBase Reference	33100-27-5(CAS DataBase Reference)
EWG's Food Scores	1
NIST Chemistry Reference	15-Crown-5(33100-27-5)
EPA Substance Registry System	1,4,7,10,13-Pentaoxacyclopentadecane (33100-27-5)
UNSPSC Code	12352200
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312+P330

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xn,Xi

Risk Statements

22-36/38-36-20/22-36/37/38-20/21/22

Safety Statements

26-39-36

RIDADR

2810

WGK Germany

RTECS

SB0200000

10-21

Hazard Note

Irritant

TSCA

TSCA listed

HazardClass

6.1(b)

PackingGroup

III

HS Code

29329995

Storage Class

10 - Combustible liquids

Hazard Classifications

Acute Tox. 4 Oral

Toxicity

LD50 orl-rat: 1410 mg/kg DCTODJ 1,339,78

REACH Registrations

Active

NFPA 704

	0
2		0

15-Crown-5 price More Price(118)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	188832	15-Crown-5 98%	33100-27-5	1g	$25.8	2026-04-30	Buy
Sigma-Aldrich	188832	15-Crown-5 98%	33100-27-5	5g	$70.3	2026-04-30	Buy
TCI Chemical	C0859	15-Crown 5-Ether >97.0%(GC)	33100-27-5	5mL	$52	2026-04-30	Buy
TCI Chemical	C0859	15-Crown 5-Ether >97.0%(GC)	33100-27-5	25mL	$136	2026-04-30	Buy
Strem Chemicals	08-0300	15-Crown-5, 98% 98%	33100-27-5	2g	$40	2026-04-30	Buy

Product number	Packaging	Price	Buy
188832	1g	$25.8	Buy
188832	5g	$70.3	Buy
C0859	5mL	$52	Buy
C0859	25mL	$136	Buy
08-0300	2g	$40	Buy

15-Crown-5 Chemical Properties,Uses,Production

use

15-crown-5 has also been used to isolate salts of oxonium ions. For example, from a solution of tetrachloroauric acid, the oxonium ion [H7O3]+ has been isolated as the salt [(H7O3)(15-crown-5)2][AuCl4].

Introduction

The single nitrogen-containing derivative of 15-crown-5 is called aza-15-crown-5; the prefix “mono” is unnecessary. When two or more nitrogen atoms are present, the standard prefixes di-, tri-, etc. are applied. The term “monoazacrowns” is used here to designate the class of macrocycles containing a single nitrogen in combination with oxygen atoms as the macrocyclic donor array.

Chemical Properties

colourless liquid

Uses

15-Crown-5 is used as an efficient phase transfer catalyst and as a complexing agent. It is used to isolate oxonium ion (H7O3)+ salts especially from a solution of tetrchloroauric acid. It catalyzes the O-alkylation of the sodium salts of carboxylic acids in the penicillin and cephalosporin series, thereby facilitating esterification reaction without usage of acid. It is also used to facilitate the Williamson synthesis of ethers with hindered alcohols and sodium hydride. It is used with lithium aluminum hydride, for performing reduction reactions in hydrocarbon solvents. Further, it is involved in the Horner-Wadsworth-Emmons reaction to prepare stilbenes from aldehydes.

Definition

ChEBI: A saturated organic heteromonocyclic parent that is cyclopentadecane in which the carbon atoms at positions 1, 4, 7, 10 and 13 have been replaced by oxygen atoms to give a crown ether.

General Description

15-Crown-5 is a crown ether generally used as a ligand in coordination chemistry because of its strong chelating property with certain alkali cations to form complexes. Some derivatives of 15-crown-5 are used as sensors and probes in different physical-chemical processes, phase-transfer reactions, and selective capture of ions for separation and transport.

Safety Profile

Moderately toxic by ingestion, skin contact, and intraperitoneal routes. A skin and eye . When heated to decomposition it emits acrid smoke and irritating fumes

Purification Methods

Dry it over 3A molecular sieves and distil it in a high vacuum. [Beilstein 19/12 V 252.]

15-Crown-5 Preparation Products And Raw materials

Raw materials

Preparation Products

METHYL 3-((PIPERIDIN-4-YL)METHYL)BENZOATE 4-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID METHYL 4-((PIPERIDIN-4-YL)METHYL)BENZOATE 2-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID 18-Crown-6

PERFLUORO-15-CROWN-5 2-METHYL-1,3-DIOXOLANE 3-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID 1-Triacontanol Chlorfluazuron

METHYL 2-((PIPERIDIN-4-YL)METHYL)BENZOATE 4-Fluoroaniline

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15-Crown-5 Suppliers

Global( 510)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5228	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	info@tnjchem.com	China	2988	55
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Hefei TNJ Chemical Industry Co.,Ltd.	55
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58

View Lastest Price from 15-Crown-5 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-05	15-Crown-5 33100-27-5		1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-05-28	15-Crown-5 33100-27-5	$2.00-5.00	1kg	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2026-05-21	15-Crown-5 33100-27-5	$23.00	1kg	99%	200mt	Jinan Finer Chemical Co., Ltd

15-Crown-5
33100-27-5
$0.00
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

15-Crown-5
33100-27-5
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

15-Crown-5
33100-27-5
$23.00
99%
Jinan Finer Chemical Co., Ltd

15-Crown-5 Spectrum

15-Crown-5(33100-27-5)MS 15-Crown-5(33100-27-5)¹HNMR 15-Crown-5(33100-27-5)¹³CNMR 15-Crown-5(33100-27-5)IR1 15-Crown-5(33100-27-5)Raman 15-Crown-5(33100-27-5)ESR

33100-27-5(15-Crown-5)Related Search:

12-Crown-4 CYCLOHEXANO-15-CROWN-5 4-T-BUTYLCYCLOHEXANO-15-CROWN-5,4-TERT-BUTYLCYCLOHEXANO-15-CROWN-5 Hydroxy-15-crown-5,2-(HYDROXYMETHYL)-15-CROWN 5-ETHER,2-HYDROXYMETHYL-15-CROWN-5 4'-FORMYLBENZO-15-CROWN-5,4'-FORMYLBENZO-15-CROWN 5-ETHER

4'-BROMOBENZO-15-CROWN-5,4'-BROMOBENZO-15-CROWN 5-ETHER,4-BROMOBENZO-15-CROWN-5 4'-NITROBENZO-15-CROWN-5,4-NITROBENZO-15-CROWN-5,4'-NITROBENZO-15-CROWN 5-ETHER DIBENZO-15-CROWN-5 4'-CARBOXYBENZO-15-CROWN-5,4-CARBOXYBENZO-15-CROWN-5,4'-CARBOXYBENZO-15-CROWN 5-ETHER 4-AMINOBENZO-15-CROWN-5 HYDROCHLORIDE,4'-AMINOBENZO-15-CROWN-5 HYDROCHLORIDE

4'-AMINOBENZO-15-CROWN 5-ETHER,4'-AMINOBENZO-15-CROWN-5 1-AZA-15-CROWN-5,1-AZA-15-CROWN 5-ETHER 4-TERT-BUTYLBENZO-15-CROWN-5,4-T-BUTYLBENZO-15-CROWN-5,tert-Butylbezno-15-crown-5 Benzo-15-crown-5 4,10-DIAZA-15-CROWN 5-ETHER,1,7-DIAZA-15-CROWN-5

4'-(2,4-DINITRO-6-TRIFLUOROMETHYLPHENYL)-AMINOBENZO-15-CROWN-5,4'-(2'',4''-DINITRO-6''-TRIFLUOROMETHYLPHENYL)-AMINOBENZO-15-CROWN-5 Dibenzodiaza-15-crown-4 2,3-NAPHTHO-15-CROWN-5

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1,4,10,13-Pentaoxacyclopentadecane 15-Crown-5,1,4,7,10,13-Pentaoxa-cyclo-pentadecane Crownethers Ethyleneoxidecyclicpentamer 15-Crown-5 Vetec(TM) reagent grade, 98% 1,4,7,1,13-Pentaoxacyclopentadecane 15-Crown-5 solution LABOTEST-BB LT00440921 LEAD IONOPHORE V CROWN ETHER/15-CROWN-5 15-CROWN-5 15-CROWN 5-ETHER 15-Crown-5, 98% 5GR 15-Crown-5, 98+% Crownpaleyellowliq 15-CROWN-5,99% CROWN ETHER/15-CROWN-5 FOR SYNTHESIS 1,4,7,10,13-Pentaoxacyclopentadecane 98% 15-crown ether-5 15-Crown-5-Ether SynonyMs 1,4,7,10,13-Pentaoxacyclopentadecane 15 - crown ether JACS-33100-27-5 15-Crown 5-Ether > 15-Crown-5, 98%, reagent grade Octadecylamide dimethylpropyl ammonium chloride 15-ether-5 1,4,7,10,13-PENTAOXACYCLOPENTADECANE 15-Crown-5 98% 15-Crown-6 crown ether 33100-27-5 33100-21-5 C10H20O5 Macrocycles for Host-Guest Chemistry Ion Sensor Materials Ionophores Potentiometric for ISE Synthetic Reagents Chelation/Complexation Compounds Analytical Chromatography Product Catalog Pyridines catalyst Crown Ethers Functional Materials Macrocycles for Host-Guest Chemistry bc0001 33100-27-5 crown ether