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2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE structure

CAS No.: 141449-85-6

Chemical Name:: 2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE

Synonyms: 2-Boc-hexahydro-pyrrpol[3...;tert-butyl hexahydropyrrolo[3;4-c]pyrrole-2(1H)-carboxylate;Pyrrolo[3,4-c]Pyrrole-2(1H)-Ca;N-BOC-3,7-Diazabicyclo[3,3,0]octane;2-Boc-Hexahydro-Pyrrol[3,4-c]Pyrrole;2-Boc-octahydropyrrolo[3,4-c]pyrrole;2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE;2-Boc-hexahydro-pyrrpol[3,4-c]pyrrole;Octahydropyrrolo[3,4-c]pyrrole, N2-BOC protected

CBNumber:: CB9711536

Molecular Formula:: C11H20N2O2

Molecular Weight:: 212.29

MDL Number:: MFCD04115128

MOL File:: 141449-85-6.mol

Last updated:2025-08-08 17:45:00

Request For Quotation

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Properties

Boiling point	295.4±33.0 °C(Predicted)
Density	1.076±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	10.72±0.20(Predicted)
form	solid
color	White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05
Signal word	Danger
Hazard statements	H314-H227
Precautionary statements	P501-P210-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405
HS Code	2933998090

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B695355	tert-ButylHexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate	141449-85-6	500mg	$175	2021-12-16	Buy
Usbiological	265699	2-Boc-hexahydropyrrolo[3,4-c]pyrrole	141449-85-6	50mg	$353	2021-12-16	Buy
Biosynth Carbosynth	FB50885	2-Boc-hexahydropyrrolo[3,4-c]pyrrole	141449-85-6	250mg	$55	2021-12-16	Buy
SynQuest Laboratories	4H56-1-581	Octahydropyrrolo[3,4-c]pyrrole, N2-Boc protected	141449-85-6	1g	$225	2021-12-16	Buy
Biosynth Carbosynth	FB50885	2-Boc-hexahydropyrrolo[3,4-c]pyrrole	141449-85-6	2g	$260	2021-12-16	Buy

Product number	Packaging	Price	Buy
B695355	500mg	$175	Buy
265699	50mg	$353	Buy
FB50885	250mg	$55	Buy
4H56-1-581	1g	$225	Buy
FB50885	2g	$260	Buy

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Chemical Properties,Uses,Production

Uses

2-Boc-Hexahydro-pyrrolo[3,4-C]pyrrole is an organic synthetic intermediate compound used in the preparation of anticancer agent compounds and sigma-2 ligands.

Synthesis

5-Benzyl-2-Boc-hexahydro-pyrrolo[3,4-C]pyrrole

186202-73-3

141449-85-6

Example 6C: Synthesis of tert-butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate To a solution of tert-butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (107.8 g, 0.356 mol), the product of Example 6B, in methanol (250 mL) was added wet 20% Pd(OH)2/C catalyst (10.8 g). The reaction mixture was hydrogenated for 2.5 hours at 50°C and 60 psi under a hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the title compound tert-butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (74 g, 0.35 mol, 98% yield). Mass spectrum (DCI/NH3) m/z: 213 ([M+H]+).

References

[1] Patent: US2005/65178, 2005, A1. Location in patent: Page/Page column 22
[2] Patent: US2005/101602, 2005, A1. Location in patent: Page/Page column 28
[3] Patent: WO2009/111550, 2009, A1. Location in patent: Page/Page column 37
[4] Patent: WO2013/71697, 2013, A1. Location in patent: Paragraph 00250
[5] Patent: US2014/228361, 2014, A1. Location in patent: Paragraph 0371-0372

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Preparation Products And Raw materials

Raw materials

5-Benzyl-2-Boc-hexahydro-pyrrolo[3,4-C]pyrrole Methanol Hydrogen

Preparation Products

JNJ-42847922 Pyrrolo[3,4-c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-(3-methoxyphenyl)-, 1,1-dimethylethyl ester Pyrrolo[3,4-c]pyrrole-2(1H)-carboxylic acid, 5-(6-chloro-3-pyridazinyl)hexahydro-, 1,1-dimethylethyl ester

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Suppliers

Global( 150)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29800	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Nanjing ChemLin Chemical Industry Co., Ltd.	60
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Labnetwork lnc.	58

View Lastest Price from 2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2022-01-27	2-Boc-hexahydro-pyrrolo[3,4-c]pyrrole 141449-85-6	US $0.00 / KG	1KG	98.0%	100 tons	Honest Joy Holdings Limited
	2020-01-03	2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE 141449-85-6	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

2-Boc-hexahydro-pyrrolo[3,4-c]pyrrole
141449-85-6
US $0.00 / KG
98.0%
Honest Joy Holdings Limited

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE
141449-85-6
US $1.00 / KG
99%
Career Henan Chemical Co

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Spectrum

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE(141449-85-6)¹HNMR

141449-85-6(2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE)Related Search:

HEXAHYDRO-PYRROLO[3,4-B]PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER HEXAHYDRO-PYRROLO[3,2-B]PYRROLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Pyrrolo[3,4-b]pyrrole-5(1H)-carboxylic acid, hexahydro-, ethyl ester 2-Boc-6-oxo-2-azaspiro[3.4]octane 2-Boc-5-oxo-octahydro-isoindole

hexahydrocyclopenta[c]pyrrol-5(1H)-one N-BOC-HEXAHYDRO-5-OXOCYCLOPENTA[C]PYRROLE (3aR,6aS)-benzyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate cis-5-Oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylic acid tert-butyl ester (Meso-3aR,5r,6aS)-tert-butyl 5-hydroxyhexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate

2-methyl-octahydrocyclopenta[c]pyrrol-5-one 2-methyl-octahydrocyclopenta[c]pyrrol-5-one (cis)-5-Boc-Hexahydro-pyrrolo[3,4-b]pyrrole,5-Boc-Hexahydro-pyrrolo[3,4-b]pyrrole CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE cis-2-Boc-hexahydropyrrolo[3,4-c]pyrrole

2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE

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HEXAHYDRO-PYRROLO[3,4-C]PYRROLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER 2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE 2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE HYDROCHLORIDE 2-Boc-hexahydro-pyrrpol[3,4-c]pyrrole Pyrrolo[3,4-c]Pyrrole-2(1H)-Ca 2-Boc-octahydropyrrolo[3,4-c]pyrrole 4-c]pyrrole-2(1H)-carboxylate tert-butyl hexahydropyrrolo[3 2-Boc-hexahydro-pyrrpol[3... tert-Butyl octahydropyrrolo[3,4-c]pyrrole-2-carboxylate 2-Boc-Hexahydro-Pyrrol[3,4-c]Pyrrole tert-butyl 2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carboxylate Octahydropyrrolo[3,4-c]pyrrole, N2-BOC protected N-BOC-3,7-Diazabicyclo[3,3,0]octane Hexahydropyrrolo3,4-cpyrrol-2-carboxylic acid tert-butyl ester tert-butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate 97% 141449-85-6 Amines and Anilines Heterocycles