4-IODO-2-METHYLANILINE
- CAS No.
- 13194-68-8
- Chemical Name:
- 4-IODO-2-METHYLANILINE
- Synonyms
- AURORA 1126;4-Iodo-2-methyL;BUTTPARK 24\04-61;AKOS BBS-00007953;4-iodo-2-methylanil;4-Iodo-o-toluidine;2-AMINO-5-IODOTOLUENE;4-IODO-2-METHYLANILINE;4-Iodo-2-Methylalinine;Aniline, 4-iodo-2-methyl-
- CBNumber:
- CB9712432
- Molecular Formula:
- C7H8IN
- Molecular Weight:
- 233.05
- MDL Number:
- MFCD00025299
- MOL File:
- 13194-68-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Iodo-2-methylaniline 97% | 454788 | 1g | $32.3 |
| 4-Iodo-2-methylaniline 97% | 454788 | 10g | $197 |
| 4-Iodo-2-methylaniline >98.0%(GC)(T) | I0690 | 5g | $32 |
| 4-Iodo-2-methylaniline >98.0%(GC)(T) | I0690 | 25g | $95 |
| 4-Iodo-2-methylaniline | I737258 | 1g | $45 |
| More product size | |||
| Melting point | 86-89 °C (lit.) |
|---|---|
| Boiling point | 278.4±28.0 °C(Predicted) |
| Density | 1.791±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 3.66±0.10(Predicted) |
| form | powder to crystal |
| color | Purple to Dark purple to Dark red |
| Sensitive | Light Sensitive |
| BRN | 2353618 |
| InChI | InChI=1S/C7H8IN/c1-5-4-6(8)2-3-7(5)9/h2-4H,9H2,1H3 |
| InChIKey | BGKLFAQCHHCZRZ-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=C(I)C=C1C |
| CAS DataBase Reference | 13194-68-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H315-H319-H332-H335-H331 | |||||||||
| Precautionary statements | P304+P340-P405-P501a-P261-P280-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36-26,36/37/39 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29214300 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-IODO-2-METHYLANILINE price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 454788 | 4-Iodo-2-methylaniline 97% | 13194-68-8 | 1g | $32.3 | 2023-01-07 | Buy |
| Sigma-Aldrich | 454788 | 4-Iodo-2-methylaniline 97% | 13194-68-8 | 10g | $197 | 2023-01-07 | Buy |
| TCI Chemical | I0690 | 4-Iodo-2-methylaniline >98.0%(GC)(T) | 13194-68-8 | 5g | $32 | 2025-07-31 | Buy |
| TCI Chemical | I0690 | 4-Iodo-2-methylaniline >98.0%(GC)(T) | 13194-68-8 | 25g | $95 | 2025-07-31 | Buy |
| TRC | I737258 | 4-Iodo-2-methylaniline | 13194-68-8 | 1g | $45 | 2021-12-16 | Buy |
4-IODO-2-METHYLANILINE Chemical Properties,Uses,Production
Chemical Properties
Grey to purple crystals
Synthesis
583-75-5
13194-68-8
General procedure for the synthesis of 4-iodo-2-methylaniline from 2-methyl-4-bromoaniline: the aromatic Finkelstein reaction is used. Since copper(I) iodide is sensitive to moisture and oxygen, the reaction is carried out under argon protection using the standard Schlenk technique. The procedure is as follows: 2-methyl-4-bromoaniline, NaI (2 equiv., relative to bromine exchange) and CuI (5 mol%, relative to bromine exchange) are added to a two-necked pear-shaped flask equipped with a reflux condenser. N,N'-dimethylethylenediamine (L1) or N,N'-dimethyl-1,2-cyclohexanediamine (L2) (10 mol%, relative to bromine exchange) and anhydrous 1,4-dioxane (0.5 mL per 1 mmol NaI) were subsequently added. The resulting suspension was heated to 110°C and reacted for 18 hours. After completion of the reaction, it was cooled to room temperature and the mixture was poured into a 25% ammonia solution. The blue solution was diluted with deionized water until doubled in volume and extracted three times with dichloromethane. If 2,2'-bipyridine was used as the ligand, the combined organic phases were additionally washed with aqueous EDTA; otherwise, the combined organic phases were washed with saturated saline only and dried with anhydrous magnesium sulfate. The solvent is removed by concentration under reduced pressure to give pure 4-iodo-2-methylaniline. If necessary, the crude product can be further purified by column chromatography or recrystallization.
Purification Methods
Crystallise it from 50% EtOH. [Beilstein 12 IV 1807.]
References
[1] Synthesis (Germany), 2014, vol. 46, # 8, p. 1085 - 1090
[2] Journal of the American Chemical Society, 2015, vol. 137, # 26, p. 8328 - 8331
4-IODO-2-METHYLANILINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8753 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29795 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from 4-IODO-2-METHYLANILINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-30 | 4-IODO-2-METHYLANILINE
13194-68-8
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-01 | 4-IODO-2-METHYLANILINE
13194-68-8
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-11-18 | 4-IODO-2-METHYLANILINE
13194-68-8
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 4-IODO-2-METHYLANILINE
13194-68-8
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-IODO-2-METHYLANILINE
13194-68-8
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-IODO-2-METHYLANILINE
13194-68-8
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
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