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4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE structure

CAS No.: 26475-62-7

Chemical Name:: 4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE

Synonyms: EOS-60875;1-DIOXIDE-4-THIOMORPHOLINEETHANOL;1-DIXOIDE-4-THIOMORPHOLINEETHANOL;4-THIOMORPHOLINEETHANOL-1-DIOXIDE;2-(1,1-DIOXOTHIOMORPHOLINO)ETHANOL;4-Thiomorpholineethanol, 1,1-dioxide;2-(1,1-DIOXO-1,4-THIAZINAN-4-YL)ETHANOL;2-(1,1-dioxidothiomorpholin-4-yl)ethanol;4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE;N-(2-HYDROXYETHYL) THIOMORPHOLINE 1,1-DIOXIDE

CBNumber:: CB9752515

Molecular Formula:: C6H13NO3S

Molecular Weight:: 179.24

MDL Number:: MFCD00106415

MOL File:: 26475-62-7.mol

Last updated:2025-07-24 18:13:49

Product description	Number	Pack Size	Price
4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide >98.0%(GC)(T)	H1140	5g	$100
4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide >98.0%(GC)(T)	H1140	25g	$296
4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide	H998233	100mg	$60
4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide	6185AL	250mg	$81
4-(2-Hydroxyethyl)thiomorpholine 1,1-dioxide 98.0%	8H63-1-2Y	1g	$95
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4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE Properties

Melting point	74 °C
Boiling point	197 °C / 1mmHg
Density	1.287±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Methanol
form	powder to crystal
pka	14.80±0.10(Predicted)
color	White to Light yellow to Light orange
InChI	InChI=1S/C6H13NO3S/c8-4-1-7-2-5-11(9,10)6-3-7/h8H,1-6H2
InChIKey	GILLKIJFJOBJCD-UHFFFAOYSA-N
SMILES	N1(CCO)CCS(=O)(=O)CC1
CAS DataBase Reference	26475-62-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
HS Code	2934999090

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	H1140	4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide >98.0%(GC)(T)	26475-62-7	5g	$100	2025-07-31	Buy
TCI Chemical	H1140	4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide >98.0%(GC)(T)	26475-62-7	25g	$296	2025-07-31	Buy
TRC	H998233	4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide	26475-62-7	100mg	$60	2021-12-16	Buy
AK Scientific	6185AL	4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide	26475-62-7	250mg	$81	2021-12-16	Buy
SynQuest Laboratories	8H63-1-2Y	4-(2-Hydroxyethyl)thiomorpholine 1,1-dioxide 98.0%	26475-62-7	1g	$95	2021-12-16	Buy

Product number	Packaging	Price	Buy
H1140	5g	$100	Buy
H1140	25g	$296	Buy
H998233	100mg	$60	Buy
6185AL	250mg	$81	Buy
8H63-1-2Y	1g	$95	Buy

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE Chemical Properties,Uses,Production

Synthesis

39093-93-1

540-51-2

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE

26475-62-7

To a stirred solution of 2-bromoethanol (11.78 mL, 165.92 mmol, 7.0 equiv) in acetonitrile (68 mL) was added potassium carbonate (9.8 g, 71.10 mmol, 3.0 equiv). The reaction mixture was stirred at room temperature for 30 minutes before thiomorpholine-1,1 -dioxide (3.2 g, 23.70 mmol, 1.0 eq.) was added. The reaction mixture was heated to reflux and stirred overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm that the feedstock was completely consumed and the target product was generated. Upon completion of the reaction, the mixture was cooled to room temperature and filtered. The filtrate was concentrated to obtain the crude product, which was subsequently purified by column chromatography using a mixture of dichloromethane and 3% methanol as eluent, resulting in 4-(2-hydroxyethyl)thiomorpholine-1,1-dioxide (2.5 g, 60.0% yield) as a brown liquid. The product was characterized by 1H NMR (DMSO-d6, 300 MHz): δ 4.50 (t, 1H), 3.51 (q, 2H), 3.07 (m, 4H), 2.95 (m, 4H), 2.58 (t, 2H); Mass Spectrometry (MS): [M + H]+ m/z 180.19 (10%).

References

[1] Patent: WO2017/149518, 2017, A1. Location in patent: Page/Page column 24; 25

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE Preparation Products And Raw materials

Raw materials

Thiomorpholine-1,1-dioxide 2-Bromoethanol Acetonitrile Potassium carbonate

Preparation Products

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE Suppliers

Global( 93)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8459	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Shanghai Time Chemicals CO., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shanghai UCHEM Inc.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58

View Lastest Price from 4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-10-13	4-(2-Hydroxyethyl)thiomorpholine-1,1-dioxide 26475-62-7	US $2.00-5.00 / kg	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
	2020-02-20	4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE 26475-62-7	US $1.00 / KG	1KG	98% HPLC	10 Tons	Career Henan Chemical Co

4-(2-Hydroxyethyl)thiomorpholine-1,1-dioxide
26475-62-7
US $2.00-5.00 / kg
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE
26475-62-7
US $1.00 / KG
98% HPLC
Career Henan Chemical Co

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE Spectrum

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE(26475-62-7)¹HNMR

26475-62-7(4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE)Related Search:

4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE Thiomorpholine Thiomorpholine-1,1-dioxide 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-3-PHENYLPROPANOIC ACID (1,1-DIOXOTHIOMORPHOLINO)ACETIC ACID MONOHYDRATE

ETHYL 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)ACETATE 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-2-PHENYLACETIC ACID 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-3-METHYLBUTANOIC ACID 2-(1,1-DIOXIDOTHIOMORPHOLIN-4-YL)PROPANOIC ACID METHYL 3-CYCLOHEXYL-2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)PROPANOATE

METHYL 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-3-PHENYLPROPANOATE 3-CYCLOHEXYL-2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)PROPANOIC ACID 4-(2-HYDROXY-1-PHENYLETHYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-2-PHENYLETHYL 3,4-DICHLOROBENZENECARBOXYLATE 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-3,3-DIMETHYLBUTANOIC ACID

4-(2-BENZYLOXY-PROPYL)-THIOMORHOLINE 1,1-DIOXIDE 2-(1,1-DIOXO-1LAMBDA6,4-THIAZINAN-4-YL)-3-(1H-INDOL-3-YL)PROPANOIC ACID 4-(2-HYDROXY-1-METHYLETHYL)-1LAMBDA6,4-THIAZINANE-1,1-DIONE

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4-(2-HYDROXYETHYL)THIOMORPHOLINE 1,1-DIOXIDE 2-(1,1-DIOXOTHIOMORPHOLINO)ETHANOL N-(2-HYDROXYETHYL) THIOMORPHOLINE 1,1-DIOXIDE 4-THIOMORPHOLINEETHANOL-1-DIOXIDE 1-DIXOIDE-4-THIOMORPHOLINEETHANOL 1-DIOXIDE-4-THIOMORPHOLINEETHANOL 4-(2-hydroxyethyl)-1$l^{6},4-thioMorpholine-1,1-dione EOS-60875 2-(1,1-DIOXO-1,4-THIAZINAN-4-YL)ETHANOL 2-(1,1-dioxidothiomorpholin-4-yl)ethanol 4-(2-Hydroxyethyl)thiomorpholine1,1-Dioxide> 4-Thiomorpholineethanol, 1,1-dioxide 4-(2-hydroxyethyl)thiomorpholine 1,1-dioxide hydrochloride 44-(2-Hydroxyethyl)thiomorpholine-1,1-dioxide 26475-62-7