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Bis-Tris propane

CAS No.
64431-96-5
Chemical Name:
Bis-Tris propane
Synonyms
B-T-Propane;1,3-BIS[TRIS(HYDROXYMETHYL)METHYLAMINO]PROPANE;yehebio;BIS-TRIS PROPANE;BIS-TRIS propane 99+%;BIS-Tris Propane, ULTROL;BIS-TRIS PROPANE SIGMAULTRA;1.0 M BIS-TRIS propane pH 8.5;1.0 M BIS-TRIS propane pH 6.6;1.0 M BIS-TRIS propane pH 8.4
CBNumber:
CB9769557
Molecular Formula:
C11H26N2O6
Molecular Weight:
282.33
MDL Number:
MFCD00004689
MOL File:
64431-96-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-20 17:44:43

Bis-Tris propane Properties

Melting point 164-165 °C(lit.)
Boiling point 573.3±50.0 °C(Predicted)
Density 1.326±0.06 g/cm3(Predicted)
storage temp. room temp
solubility H2O: 1 M at 20 °C, clear, colorless
form Powder/Solid
color White
PH 9.0-10.1 (20-25℃, 1M in water)
pka (1) 6.8, (2) 9.0(at 25℃)
PH Range 6.3 - 9.5
biological source synthetic
Water Solubility Soluble in water.
BRN 1786109
Major Application diagnostic assay manufacturing
InChI InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
InChIKey HHKZCCWKTZRCCL-UHFFFAOYSA-N
SMILES C(NC(CO)(CO)CO)CCNC(CO)(CO)CO
CAS DataBase Reference 64431-96-5(CAS DataBase Reference)
FDA UNII N5YD0CS4DO
Absorption ≤0.05 at 290 at 30% (w/w)
UNSPSC Code 12161705
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  22-24/25-26-36
WGK Germany  3
HS Code  29221980
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
1 1

Bis-Tris propane price More Price(94)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHG0005 BIS-TRIS propane 64431-96-5 1KIT $1930 2026-04-30 Buy
Sigma-Aldrich B6755 BIS-TRIS propane ≥99.0% (titration) 64431-96-5 10 kg $7580 2026-04-30 Buy
Sigma-Aldrich B4679 BIS-TRIS propane BioPerformance Certified, cell culture tested, ≥99.0% 64431-96-5 25g $119 2026-04-30 Buy
Sigma-Aldrich B4679 BIS-TRIS propane BioPerformance Certified, cell culture tested, ≥99.0% 64431-96-5 100g $336 2026-04-30 Buy
Sigma-Aldrich 394111 BIS-TRIS propane ULTROL® Grade, >98% (titration), non-zwitterionic buffer useful in pH range 6.3-9.5 64431-96-5 100 g $258 2025-07-31 Buy
Product number Packaging Price Buy
PHG0005 1KIT $1930 Buy
B6755 10 kg $7580 Buy
B4679 25g $119 Buy
B4679 100g $336 Buy
394111 100 g $258 Buy

Bis-Tris propane Chemical Properties,Uses,Production

Description

BIS-TRIS Propane is Good′s buffer. It acts as ligand and forms series of dinuclear hydroxo complexes with Lanthanides(III) in the pH range 7-9. It is useful for diagnostic assay manufacturing industry.

Chemical Properties

White powder

Uses

BIS-Tris Propane is a buffer that is useful in the pH 6.3 - 9.5 range. This wide buffering range is due to its two pKa values, 6.8 (pKa1) and 9.0 (pKa2), being so close. Because of the wide buffering range, particularly down to pH 6 - 7, this buffer has been used to enhance the stability or activity of restriction enzymes, compared to Tris buffer (which is a poor buffer below pH 7.5 and has a comparatively large change in pKa with temperature).

Uses

BIS-TRIS Propane may be used in the following studies:

  • As buffer to investigate the influence of anions with varying nucleophilic properties on the autoxidation of oxymyoglobin (MbO2).
  • Purification of glucose-binding protein from membranes of Sulfolobus solfataricus.
  • As buffer during GeO2 mineralisation.

Definition

ChEBI: Bis-tris propane is a water-soluble buffer substance used for the preparation of the biochemical and biological buffer solutions; pKa = 6.8 at 20 ℃. It has a role as a buffer. It is functionally related to a member of tris.

Precautions

This trihydroxyamine analog, also known as bis-tris propane, presents as a white to almost white crystalline powder. Store in a cool and dark place. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is known to be incompatible with oxidizing agents and should not be handled in their vicinity.

Bis-Tris propane Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 456)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Bingochem Co., Ltd. 0571-87658025 sales@bingochem.com China 21532 58
Hunan Hengfei bio-pharmaceutical Co. , Ltd. 0746-6222194 13874779848 57182844@qq.com China 52 58
Wuhan haorong Biotechnology Co., Ltd 13217229939 773651767@qq.com China 4498 58
Zhengzhou Runkai Pharmaceutical Technology Co., Ltd 19137644811 3649307081@qq.com China 496 58
Jiangsu Boquan Biotechnology Co., Ltd. 19709916022 5954981@qq.com China 2458 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56

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View Lastest Price from Bis-Tris propane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BIS-TRIS propane pictures 2026-09-11 BIS-TRIS propane
64431-96-5
$10.00-204.00 25g 0.99 25kg Shanghai UCHEM Inc.
Bis-Tris propane pictures 2026-09-11 Bis-Tris propane
64431-96-5
$666.00-999.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
1,3-Bis[tris(hydroxymethyl)methylamino]propane pictures 2026-09-11 1,3-Bis[tris(hydroxymethyl)methylamino]propane
64431-96-5
1KG 99% 3500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
  • Bis-Tris propane pictures
  • Bis-Tris propane
    64431-96-5
  • $666.00-999.00
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Bis Tris propane 1,3-Bis[tris(hydroxymethyl)methylamino]propane bis-tris propane molecular biology*reagent BIS-Tris Propane, ULTROL Grade Bistrishydroxymethylmethylaminopropane 2,2'-(propane-1,3-diyldiimino)bis[2-(hydroxymethyl)propane-1,3-diol] BIS-TRIS PROPANE, BIOTECHNOLOGY PERFORMA NCE CERTIFI BIS-TRIS PROPANE SIGMAULTRA BIS-TRIS PROPANE 1,3-Bis[tris(hydroxymethyl)methylamino]propane >99% 1,3-Bis[tris(hydroxymethyl)methylamino]propane, 98+% 1,3-Bistris(hydroxymethyl)methylaminoüpropane, 98+% 2-(((3-((1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)propyl)amino)methyl)-2-(hydroxymethyl)propane-1,3-diol 2-[3-[1,3-dihydroxypropan-2-yl(hydroxymethyl)amino]propyl-(hydroxymethyl)amino]propane-1,3-diol 3-bis[tris(Hydroxymethyl)methylamino]propane 2,2'-(1,3-Propanediylbisimino)bis[2-(hydroxymethyl)-1,3-propanediol] 2,2'-(1,3-Propanediyldiimino)bis[2-(hydroxymethyl)-1,3-propanediol] 2,2'-[1,3-Propanediylbis(imino)]bis[2-(hydroxymethyl)-1,3-propanediol] N,N'-(1,3-Propanediyl)bis[N-[1,1-bis(hydroxymethyl)-2-hydroxyethyl]amine] Trimethylenebis(iminomethanetetrayl)hexakismethanol 1,3-Bis[Tris(hydroxyethyl)MethylaMino] Propane 2,2'-(propane-1,3-diylbis(azanediyl))bis(2-(hydroxyMethyl)propane-1,3-diol) 1,3-Bis[tris(hydroxyMethyl)MethylaMino]propane SynonyMs BIS-TRIS propane BIS-Tris Propane, ULTROL BIS-TRIS propane, CellPURE?, Cell culture tested 1,3-Bis[tris(hydroxymethyl)amino]propane, 99% BIS-TRIS propane 99+% 1,3-Propanediol, 2,2'-(1,3-propanediyldiimino)bis[2-(hydroxymethyl)- 2-[3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propylamino]-2-(hydroxymethyl)propane-1,3-diol 1,3-Bis ((trihydroxymethyl) methylamino) propane(BIS-TRIS) 1,3-Bis ((trihydroxymethyl) methylamino) propane Bis[tris(hydroxymethyl)aminopropane yehebio BIS-TRIS propane, 10 mM in DMSO BIS-TRISPROPANE,BIOLOGICALBUFFER 1,3-Bis[tris(hydroxymethyl)methylamino]propane [for Buffer Material] 1,3-Bis[tris(hydroxyMethyl)MethylaMino]propane, 99%, suitable for buffer solutions 1,3-Bis[tris(hydroxyMethyl)MethylaMino]propane, for buffer solutions 1,3-Bis[tris(hydroxymethyl)methylamino]propane, 99%, for buffer solutions 1,3-Bis[tris(hydroxymethyl)methylamino]propane [for Buffer Material]> BIS-TRIS Propane Buffer extrapure, 99% 1,3-Bis (trihydroxymethylamino) propane Bis-Tris Propane Buffer 0.2M, pH 7.0 Bis-Tris Propane Buffer 0.2M, pH 7.5 Bis-Tris Propane Buffer 0.5M, pH 6.5 Bis-Tris Propane Buffer 1M, pH 9.0 Bis-Tris Propane Buffer 1M, pH 7.0 1.0 M BIS-TRIS propane pH 8.5 1.0 M BIS-TRIS propane pH 6.6 1.0 M BIS-TRIS propane pH 8.4 1.0 M BIS-TRIS propane pH 7.6 1.0 M BIS-TRIS propane pH 6.8 1.0 M BIS-TRIS propane pH 8.8 1.0 M BIS-TRIS propane pH 7.8 1.0 M BIS-TRIS propane pH 8.1 1.0 M BIS-TRIS propane pH 7.5 1.0 M BIS-TRIS propane pH 7.0 1.0 M BIS-TRIS propane pH 7.4 1.0 M BIS-TRIS propane pH 9.2