Methyl 2-amino-3-methylbenzoate
- CAS No.
- 22223-49-0
- Chemical Name:
- Methyl 2-amino-3-methylbenzoate
- Synonyms
- Methyl 2-amino-3-met;Methyl 2-Amino-m-toluate;methyl 3-methylanthranilate;Methyl 2-aMino-3-Methylbe...;Methyl 2-mino-3-Methylbenzoate;Methyl 3-methyl-2-aminobenzoate;METHYL 2-AMINO-3-METHYLBENZOATE;Methyl2-Amino-3-methylbenzoate>2-Amino-m-toluic Acid Methyl Ester;Methyl 2-amino-3-methylbenzoate 98%
- CBNumber:
- CB9773134
- Molecular Formula:
- C9H11NO2
- Molecular Weight:
- 165.19
- MDL Number:
- MFCD06200918
- MOL File:
- 22223-49-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl 2-Amino-3-methylbenzoate >98.0%(GC)(T) | M2193 | 5g | $45 |
| Methyl 2-Amino-3-methylbenzoate >98.0%(GC)(T) | M2193 | 25g | $176 |
| 2-Amino-3-methylbenzoicAcidMethylEster | A612155 | 50g | $250 |
| 2-Amino-3-methylbenzoicAcidMethylEster | A612155 | 5g | $50 |
| Methyl 2-amino-3-methylbenzenecarboxylate 95+% | 043125 | 25g | $41 |
| More product size | |||
| Melting point | 115-117°C |
|---|---|
| Boiling point | 153℃/23mm |
| Density | 1.132±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 2.05±0.10(Predicted) |
| form | Solid |
| color | Pink |
| FreezingPoint | 25.0 to 29.0 ℃ |
| InChI | 1S/C9H11NO2/c1-6-4-3-5-7(8(6)10)9(11)12-2/h3-5H,10H2,1-2H3 |
| InChIKey | VSFYTPXXMLJNAU-UHFFFAOYSA-N |
| SMILES | O=C(OC)C1=C(N)C(C)=CC=C1 |
| CAS DataBase Reference | 22223-49-0(CAS DataBase Reference) |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2922498590 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
Methyl 2-amino-3-methylbenzoate price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2193 | Methyl 2-Amino-3-methylbenzoate >98.0%(GC)(T) | 22223-49-0 | 5g | $45 | 2026-04-30 | Buy |
| TCI Chemical | M2193 | Methyl 2-Amino-3-methylbenzoate >98.0%(GC)(T) | 22223-49-0 | 25g | $176 | 2026-04-30 | Buy |
| TRC | A612155 | 2-Amino-3-methylbenzoicAcidMethylEster | 22223-49-0 | 50g | $250 | 2021-12-16 | Buy |
| TRC | A612155 | 2-Amino-3-methylbenzoicAcidMethylEster | 22223-49-0 | 5g | $50 | 2021-12-16 | Buy |
| Matrix Scientific | 043125 | Methyl 2-amino-3-methylbenzenecarboxylate 95+% | 22223-49-0 | 25g | $41 | 2021-12-16 | Buy |
Methyl 2-amino-3-methylbenzoate Chemical Properties,Uses,Production
Chemical Properties
Pale brown liquid
Uses
2-Amino-3-methylbenzoic Acid Methyl Ester is the methyl ester derivative of 2-Amino-3-methylbenzoic Acid (A612150); a metabolite of Lidocaine (L397800) with potential herbicidal activity. 2-Amino-3-methylbenzoic Acid Methyl Ester is also used as the starting material in the synthesis of N-(2-Methoxyacetate)-N-(2-carboxy-6-methylphenyl)-alanine (M260810); a metabolite of Metalaxyl (M258740) which is an agricultural fungicide.
Synthesis
5471-82-9
22223-49-0
The general steps for synthesizing methyl 2-amino-3-methylbenzoate from methyl 3-methyl-2-nitrobenzoate are as follows: Step A: Preparation of methyl 2-amino-3-methylbenzoate Methyl 3-methyl-2-nitrobenzoate (98.5 g, 505 mmol), 5% Pd/C (Degussa CE 105 XRCAV, 1.0 g) and acetonitrile (300 mL) were mixed in a 600 mL pressure vessel. The mixture was heated to 70°C and hydrogenated at 65 psi (450 kPa) under hydrogen pressure for 8 hours. Subsequently, 5% Pd/C (1.0 g) was added supplementally and hydrogenation was continued for 8.5 hours at 100 psi (690 kPa) hydrogen pressure. Upon completion of the reaction, the reaction mixture was cooled to room temperature, the hydrogen in the reactor was replaced with nitrogen, and then filtered through a Celite diatomaceous earth filter aid. The filter cake was washed with acetonitrile (3 x 25 mL). The combined filtrates were concentrated to about 160 g, and then the total weight was adjusted with acetonitrile to 200 g. The amount of the title compound in solution was measured to be 40.3 wt%, or 80.6 g, in 97.5% yield by quantitative HPLC analysis.
References
[1] Tetrahedron, 2013, vol. 69, # 32, p. 6679 - 6686
[2] Patent: WO2006/62978, 2006, A1. Location in patent: Page/Page column 23
[3] Asian Journal of Chemistry, 2014, vol. 26, # 7, p. 1921 - 1930
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 30, p. 5629 - 5633
[5] Chemische Berichte, 1907, vol. 40, p. 4413
Methyl 2-amino-3-methylbenzoate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10404 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from Methyl 2-amino-3-methylbenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-30 | Methyl 2-amino-3-methylbenzoate
22223-49-0
|
US $0.00-0.00 / kg | 1kg | 99.0%min | 10tons | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2025-12-01 | Methyl 2-amino-3-methylbenzoate
22223-49-0
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-06-27 | Methyl 2-amino-3-methylbenzoate
22223-49-0
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Methyl 2-amino-3-methylbenzoate
22223-49-0
- US $0.00-0.00 / kg
- 99.0%min
- Asia Chem I and E (Jiangsu) Co Ltd
-
- Methyl 2-amino-3-methylbenzoate
22223-49-0
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- Methyl 2-amino-3-methylbenzoate
22223-49-0
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
