4-Methylthiophene-2-boronic acid
- CAS No.
- 162607-15-0
- Chemical Name:
- 4-Methylthiophene-2-boronic acid
- Synonyms
- RARECHEM AH PB 0204;2-Borono-4-methylthiophene;4-METHYL-2-THIENYLBORIC ACID;4-METHYL-2-THIENYLBORONIC ACID;4-METHYLTHIOPHENE-2-BORONIC ACID;4-Methyl-2-thiopheneboronic Acid;(4-Methylthiophen-2-yl)boronic acid;4-METHYLTHIOPHENE-2-BORONIC ACID 96%;4-Methylthiophene-2-boronic acid,96%;Boronic acid, B-(4-Methyl-2-thienyl)-
- CBNumber:
- CB9782589
- Molecular Formula:
- C5H7BO2S
- Molecular Weight:
- 141.98
- MDL Number:
- MFCD01319040
- MOL File:
- 162607-15-0.mol
| Product description | Number | Pack Size | Price |
| 4-methylthiophene-2-boronic acid AldrichCPR | CDS003645 | 250 mg | $87.5 |
| 4-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) | M2840 | 1g | $68 |
| 4-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) | M2840 | 5g | $224 |
| 4-Methylthiophene-2-boronicAcid | M725530 | 100mg | $75 |
| 4-Methyl-2-thiopheneboronicacid,97-105%(Assaybytitration) 97-105%(Assaybytitration) | 40381 | 1G | $58.24 |
| Melting point | 125-126 °C |
|---|---|
| Boiling point | 305.4±44.0 °C(Predicted) |
| Density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| form | Powder |
| pka | 8.51±0.53(Predicted) |
| color | White to light beige |
| InChI | 1S/C5H7BO2S/c1-4-2-5(6(7)8)9-3-4/h2-3,7-8H,1H3 |
| InChIKey | DFUMIZDUIJNUJU-UHFFFAOYSA-N |
| SMILES | Cc1csc(c1)B(O)O |
| CAS DataBase Reference | 162607-15-0(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-41-37/38 | |||||||||
| Safety Statements | 37/39-26-39 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29310099 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Methylthiophene-2-boronic acid price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS003645 | 4-methylthiophene-2-boronic acid AldrichCPR | 162607-15-0 | 250 mg | $87.5 | 2025-07-31 | Buy |
| TCI Chemical | M2840 | 4-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) | 162607-15-0 | 1g | $68 | 2025-07-31 | Buy |
| TCI Chemical | M2840 | 4-Methyl-2-thiopheneboronic Acid (contains varying amounts of Anhydride) | 162607-15-0 | 5g | $224 | 2025-07-31 | Buy |
| TRC | M725530 | 4-Methylthiophene-2-boronicAcid | 162607-15-0 | 100mg | $75 | 2021-12-16 | Buy |
| Chem-Impex | 40381 | 4-Methyl-2-thiopheneboronicacid,97-105%(Assaybytitration) 97-105%(Assaybytitration) | 162607-15-0 | 1G | $58.24 | 2021-12-16 | Buy |
4-Methylthiophene-2-boronic acid Chemical Properties,Uses,Production
Uses
4-Methylthiophene-2-boronic acid is a thiophene derivative widely used in the synthesis of pesticides, pharmaceuticals, chemical reagents, dyes, and polymer auxiliaries.
Chemical Properties
White to light yellow crystal powde
Synthesis
3.0 g (8.85 mmol) of potassium phosphate heptahydrate, 1.50 g (5.90 mmol) of bis(boronic acid) pinacol ester B2(pin)2, 12 mg (0.015 mmol) of Xphos-Pd-G2, and 4 mg (0.008 mmol) of Xphos were added sequentially to a reaction vial with 6 mL of ethanol stirred to mix well, followed by 0.36 mL of (2.95 mmol) 4-methylthiophene-2-chloride was added and the reaction was carried out at room temperature for 1 hour. The reaction solution was diluted by adding 5mL of ethyl acetate, filtered through diatomaceous earth, washed with ethyl acetate, the filtrates were combined and concentrated under reduced pressure to obtain the crude product, which was separated by silica gel column chromatography, eluted with petroleum ether-ethyl acetate to obtain 4-methylthiophene-2-boronic acid pinacol ester. 4-Methyl thiophene-2-boronic acid pinacol ester was added to the reaction flask and hydrolyzed dropwise with dilute HCl. The solution first produced a precipitate, with the precipitate gradually disappeared, adjust the system pH value of 1. To the solution of NaOH solution with a mass fraction of 25% was added dropwise to pH 13, stirring for 1 h. Separation of the liquid, the organic phase was extracted with 15 mL of NaOH with a mass fraction of 10%, and the aqueous phase was combined, and the alkaline solution was extracted with 15 mL of THF for 2 times, respectively. The pH of the obtained base solution was adjusted with dilute HCl, turbidity was generated at the beginning, flocculent appeared slowly, and the pH was adjusted to 5.0. The aqueous phase was extracted with 70 mL of THF, and the organic phase was spin-dried and purified to obtain 4-methylthiophene-2-boronic acid.
4-Methylthiophene-2-boronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
4-Methylthiophene-2-boronic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49964 | 58 |
| Shanghai Scochem Technology Co., Ltd | +86-021-33758897 +86-13701882790 | sales@scochem.com | China | 1977 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
View Lastest Price from 4-Methylthiophene-2-boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 4-Methylthiophene-2-boronic acid
162607-15-0
|
US $1.00 / KG | 1KG | 97%-99% | 1kg;5kg;100kg | Career Henan Chemical Co |
-
- 4-Methylthiophene-2-boronic acid
162607-15-0
- US $1.00 / KG
- 97%-99%
- Career Henan Chemical Co
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