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5-FLUORO-2-METHOXYBENZALDEHYDE

5-FLUORO-2-METHOXYBENZALDEHYDE structure

CAS No.: 19415-51-1

Chemical Name:: 5-FLUORO-2-METHOXYBENZALDEHYDE

Synonyms: 5-FLUORO-O-ANISALDEHYDE;5-Fluoro-o-anisaldehyde>5-Fluoro-o-methoxybenzaldehy;5-FLUORO-2-METHOXYBENZALDEHYDE;2-METHOXY-5-FLUOROBENZALDEHYDE;5-Fluoro-o-anisaldehyde;5-Fluoro-o-2-methoxybenzaldehyde;Benzaldehyde,5-fluoro-2-methoxy-;5-FLUORO-2-METHOXYBEZALDEHYDE, 96%;5-Fluoro-2-methoxybenzaldehyde,99%

CBNumber:: CB9783142

Molecular Formula:: C8H7FO2

Molecular Weight:: 154.14

MDL Number:: MFCD00143458

MOL File:: 19415-51-1.mol

MSDS File:: SDS

Last updated:2026-01-13 11:27:06

Product description	Number	Pack Size	Price
5-Fluoro-2-methoxybenzaldehyde 96%	523100	1g	$25
5-Fluoro-o-anisaldehyde >97.0%(GC)	F0428	1g	$32
5-Fluoro-o-anisaldehyde >97.0%(GC)	F0428	5g	$108
5-Fluoro-2-methoxybenzaldehyde	F401505	100mg	$75
5-Fluoro-2-methoxybenzaldehyde 98%	JK612860	1g	$76
More product size

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5-FLUORO-2-METHOXYBENZALDEHYDE Properties

Melting point	41-46 °C (lit.)
Boiling point	118 °C / 14mmHg
Density	1.192±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	powder to lump
color	White to Almost white
Sensitive	Air Sensitive
InChI	1S/C8H7FO2/c1-11-8-3-2-7(9)4-6(8)5-10/h2-5H,1H3
InChIKey	CRLDWFVRQNUUSZ-UHFFFAOYSA-N
SMILES	COc1ccc(F)cc1C=O
CAS DataBase Reference	19415-51-1(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Xn,Xi

Risk Statements

36/37/38-22

Safety Statements

37/39-26-36-24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29130000

Storage Class

13 - Non Combustible Solids

NFPA 704

	0
2		0

5-FLUORO-2-METHOXYBENZALDEHYDE price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	523100	5-Fluoro-2-methoxybenzaldehyde 96%	19415-51-1	1g	$25	2023-06-20	Buy
TCI Chemical	F0428	5-Fluoro-o-anisaldehyde >97.0%(GC)	19415-51-1	1g	$32	2025-07-31	Buy
TCI Chemical	F0428	5-Fluoro-o-anisaldehyde >97.0%(GC)	19415-51-1	5g	$108	2025-07-31	Buy
TRC	F401505	5-Fluoro-2-methoxybenzaldehyde	19415-51-1	100mg	$75	2021-12-16	Buy
Frontier Specialty Chemicals	JK612860	5-Fluoro-2-methoxybenzaldehyde 98%	19415-51-1	1g	$76	2021-12-16	Buy

Product number	Packaging	Price	Buy
523100	1g	$25	Buy
F0428	1g	$32	Buy
F0428	5g	$108	Buy
F401505	100mg	$75	Buy
JK612860	1g	$76	Buy

5-FLUORO-2-METHOXYBENZALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

Pale yellow powder and lumps

Uses

5-Fluoro-2-methoxybenzaldehyde may be used in the synthesis of 5-(5-fluoro-2-methoxyphenyl)imidazolidine-2,4-dione.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 3145, 1988 DOI: 10.1021/jo00249a004
Synthetic Communications, 19, p. 2001, 1989 DOI: 10.1080/00397918908052593

General Description

5-Fluoro-2-methoxybenzaldehyde is an aryl fluorinated building block.

Synthesis

452-08-4

68-12-2

19415-51-1

Synthesis of compound 1.2. 2-Bromo-4-fluoroanisole (100 g, 487.75 mmol, 1.00 equiv) and THF (1.5 L) were added to a 3000 mL three-necked round-bottomed flask under nitrogen protection. With stirring at -78 °C, n-butyllithium (n-BuLi, 215.6 mL) was added slowly and dropwise. The reaction mixture was continued stirring at -78 °C for 1 hour. Subsequently, N,N-dimethylformamide (DMF, 71.54 g, 978.79 mmol, 2.01 eq.) was added slowly and dropwise at the same temperature. The reaction system was warmed up to room temperature and stirred for 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of 800 mL of aqueous ammonium chloride (NH4Cl aq.). The reaction mixture was extracted with 500 mL of ethyl acetate, the organic layers were combined and concentrated under reduced pressure. The crude product was purified by column chromatography to afford 65.7 g (87% yield) of 5-fluoro-2-methoxybenzaldehyde (1.2) as a light yellow solid.

References

[1] Patent: WO2017/91600, 2017, A1. Location in patent: Paragraph 0386-0387
[2] Patent: US2017/166584, 2017, A1. Location in patent: Paragraph 0418-0420
[3] Journal of Organic Chemistry, 2013, vol. 78, # 12, p. 5955 - 5963

5-FLUORO-2-METHOXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

2-Bromo-4-fluoroanisole N,N-Dimethylformamide n-Butyllithium Tetrahydrofuran

Preparation Products

5-FLUORO-2-METHOXYCINNAMIC ACID

5-FLUORO-2-METHOXYBENZALDEHYDE Suppliers

Global( 202)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1445	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1010@dideu.com	China	3967	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58

View Lastest Price from 5-FLUORO-2-METHOXYBENZALDEHYDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-01-05	5-Fluoro-2-methoxybenzaldehyde 19415-51-1	US $0.00-0.00 / KG	10mg	99%HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd
	2020-01-03	5-FLUORO-2-METHOXYBENZALDEHYDE 19415-51-1	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

5-Fluoro-2-methoxybenzaldehyde
19415-51-1
US $0.00-0.00 / KG
99%HPLC
Shaanxi Dideu Medichem Co. Ltd

5-FLUORO-2-METHOXYBENZALDEHYDE
19415-51-1
US $1.00 / KG
99%
Career Henan Chemical Co

5-FLUORO-2-METHOXYBENZALDEHYDE Spectrum

5-FLUORO-2-METHOXYBENZALDEHYDE(19415-51-1)MS 5-FLUORO-2-METHOXYBENZALDEHYDE(19415-51-1)¹HNMR 5-FLUORO-2-METHOXYBENZALDEHYDE(19415-51-1)IR

19415-51-1(5-FLUORO-2-METHOXYBENZALDEHYDE)Related Search:

Methyl 5-fluoro-2-methyl-3-nitrobenzoate METHYL 2-METHYL-5-FLUOROBENZOATE 5-Fluoro-2-methylbenzoic acid 5-FLUORO-2-METHOXYBENZONITRILE 5-Fluoro-2-methoxyphenyl acetic acid

5-Fluoro-2-methoxyphenol 5-FLUORO-2-METHOXYACETOPHENONE 6-Fluoro-4-chromanone 5-FLUORO-2-METHOXYBENZALDEHYDE 2-Fluoro-3-methoxybenzaldehyde 96%,2-Fluoro-3-methoxybenzaldehyde96%,2-FLUORO-3-METHOXYBENZALDEHYDE

2-Fluoro-4-methoxybenzaldehyde97%,2-Fluoro-4-methoxybenzaldehyde 97%,2-FLUORO-4-METHOXYBENZALDEHYDE 4-(4-FLUOROBENZYLOXY)BENZALDEHYDE 3-CHLORO-5-FLUORO-4-METHOXYBENZALDEHYDE 6-CHLORO-2-FLUORO-3-METHOXYBENZALDEHYDE 2,3-DIFLUORO-6-METHOXYBENZALDEHYDE

3,5-Difluoro-4-methoxybenzaldehyde 6-FLUORO-2-METHYL-4-CHROMANONE 6-FLUORO-3-FORMYLCHROMONE

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5-Fluoro-2-methoxybenzaldehyde,99% 5-FLUORO-2-METHOXYBEZALDEHYDE, 96% 5-Fluoro-o-2-methoxybenzaldehyde 5-Fluoro-o-methoxybenzaldehy 2-METHOXY-5-FLUOROBENZALDEHYDE 5-FLUORO-2-METHOXYBENZALDEHYDE 5-FLUORO-O-ANISALDEHYDE 5-Fluoro-2-methoxybenzaldehyde,5-Fluoro-o-anisaldehyde 4-Fluoro-2-formylanisole, 5-Fluoro-o-anisaldehyde 5-Fluoro-2-methoxybenzaldehyde 96% 5-Fluoro-o-anisaldehyde Benzaldehyde,5-fluoro-2-methoxy- 5-Fluoro-o-anisaldehyde> 19415-51-1 Organic Building Blocks Carbonyl Compounds C8 Building Blocks Aldehydes Aromatic Aldehydes & Derivatives (substituted) Benzaldehyde Adehydes, Acetals & Ketones Anisoles, Alkyloxy Compounds & Phenylacetates Fluorine Compounds