ChemicalBook >> CAS DataBase List >>DBCO-PEG2-acid

DBCO-PEG2-acid

CAS No.
2304558-25-4
Chemical Name:
DBCO-PEG2-acid
Synonyms
DBCO-PEG2-COOH;DBCO-PEG2-PA;DBCO-PEG2-acid
CBNumber:
CB98054697
Molecular Formula:
C26H28N2O6
Molecular Weight:
464.51
MDL Number:
MFCD31811447
MOL File:
2304558-25-4.mol
MSDS File:
SDS
Last updated:2026-05-28 06:12:24
Product description Number Pack Size Price
DBCO-PEG2-acid 97% bp-24290 25MG $170
DBCO-PEG2-acid 97% bp-24290 100MG $380
DBCO-PEG2-acid 97% bp-24290 250MG $850
DBCO-PEG2-acid 97.00% X196924 100MG $345
DBCO-PEG2-acid 97.00% X196924 250MG $715

DBCO-PEG2-acid Properties

Boiling point 803.0±65.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
storage temp. -20°C, protect from light
solubility Soluble in DMSO, DCM, DMF
pka 4.28±0.10(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

DBCO-PEG2-acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm bp-24290 DBCO-PEG2-acid 97% 2304558-25-4 25MG $170 2026-05-24 Buy
BroadPharm bp-24290 DBCO-PEG2-acid 97% 2304558-25-4 100MG $380 2026-05-24 Buy
BroadPharm bp-24290 DBCO-PEG2-acid 97% 2304558-25-4 250MG $850 2026-05-24 Buy
ACHEMBLOCK X196924 DBCO-PEG2-acid 97.00% 2304558-25-4 100MG $345 2026-05-27 Buy
ACHEMBLOCK X196924 DBCO-PEG2-acid 97.00% 2304558-25-4 250MG $715 2026-05-27 Buy
Product number Packaging Price Buy
bp-24290 25MG $170 Buy
bp-24290 100MG $380 Buy
bp-24290 250MG $850 Buy
X196924 100MG $345 Buy
X196924 250MG $715 Buy

DBCO-PEG2-acid Chemical Properties,Uses,Production

Description

DBCO-PEG2-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. The hydrophilic PEG chain allows for increased water solubility. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

DBCO-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DBCO-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

DBCO-PEG2-acid Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13901 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
XIAMEN SINOPEG BIOTECH CO., LTD.
+86-0592-7761068 +8617350879715 changaiwei@sinopeg.com China 1125 58
Alfa Chemistry
+1-5166625404; Info@alfa-chemistry.com United States 20405 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39039 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
XIAMEN EQUATION CHEMICAL CO.,LTD
+86-5926515854 +86-18060954864 sales@equationchemical.com China 2998 58
Bide Pharmatech Ltd. 400-400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Send Pharmaceutical Technology Co., Ltd. 021-58088081 18317173152 Hailey@shsendpharm.com China 914 55
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80534353 19917294565 et@chemextension.com China 3855 55

View Lastest Price from DBCO-PEG2-acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DBCO-PEG2-acid pictures 2026-04-22 DBCO-PEG2-acid
2304558-25-4
US $65.00-42.00 / mg 10g TargetMol Chemicals Inc.
DBCO-PEG2-PA pictures 2026-02-05 DBCO-PEG2-PA
2304558-25-4
US $0.00-0.00 / g 1g 98% 1g/bottle, 10g/bottle, 100g/bottle XIAMEN SINOPEG BIOTECH CO., LTD.
  • DBCO-PEG2-acid pictures
  • DBCO-PEG2-acid
    2304558-25-4
  • US $65.00-42.00 / mg
  • TargetMol Chemicals Inc.
  • DBCO-PEG2-PA pictures
  • DBCO-PEG2-PA
    2304558-25-4
  • US $0.00-0.00 / g
  • 98%
  • XIAMEN SINOPEG BIOTECH CO., LTD.

DBCO-PEG2-acid Spectrum

DBCO-PEG2-acid DBCO-PEG2-PA DBCO-PEG2-COOH 2304558-25-4