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Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester

Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester Structure
Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester structure
CAS No.
1380600-06-5
Chemical Name:
Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester
Synonyms
Activated EG3 Tail;Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester
CBNumber:
CB98334764
Molecular Formula:
C43H47N3O10
Molecular Weight:
765.85
MDL Number:
MOL File:
1380600-06-5.mol
Last updated:2025-04-17 18:22:24
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Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester Properties

Boiling point 826.5±75.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
pka 5.66±0.10(Predicted)

Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester Chemical Properties,Uses,Production

Uses

Activated EG3 Tail can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy[1].

References

[1] Passini MA, et al. Exon skipping oligomer conjugates for muscular dystrophy. World Intellectual Property Organization, WO2018118599 A1. 2018-06-28.

Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester Preparation Products And Raw materials

Raw materials

Preparation Products

Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 8365 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Shandong utilizing biological technology co., LTD 15966937598 3407650895@qq.com China 1785 58
Jiangsu Magic Biotechnology Co., Ltd 13921770081 svp01@magicbiotech.cn China 499 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29547 58
Taizhou Chuanxu Pharmaceutical Technology Co., Ltd. 13000000000 974144639@qq.com China 9883 58
Qingdao Fansen Biotechnology Co., Ltd 18661607483 qddxhn@163.com China 210 58
Supplier Advantage
Shanghai UCHEM Inc. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Shandong utilizing biological technology co., LTD 58
Jiangsu Magic Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Taizhou Chuanxu Pharmaceutical Technology Co., Ltd. 58
Qingdao Fansen Biotechnology Co., Ltd 58
Butanedioic acid, 1-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl] 4-[2-[2-[2-[[[4-(triphenylmethyl)-1-piperazinyl]carbonyl]oxy]ethoxy]ethoxy]ethyl] ester Activated EG3 Tail 1380600-06-5 C43H47N3O10