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Diethyl succinate

CAS No.
123-25-1
Chemical Name:
Diethyl succinate
Synonyms
diethyl butanedioate;Clorius;ETHYL SUCCINATE;SUCCINIC ACID DIETHYL ESTER;BUTANEDIOIC ACID DIETHYL ESTER;Diethylester kyseliny jantarove;Diethyl ester of butanedioic acid;FEMA 2377;Diethyl succite;Diethylsuccinat
CBNumber:
CB9852963
Molecular Formula:
C8H14O4
Molecular Weight:
174.19
MDL Number:
MFCD00009208
MOL File:
123-25-1.mol
MSDS File:
SDS
Last updated:2025-09-30 18:11:34

Diethyl succinate Properties

Melting point -20 °C (lit.)
Boiling point 218 °C (lit.)
Density 1.047 g/mL at 25 °C (lit.)
vapor density 6 (vs air)
vapor pressure 1.33 hPa (55 °C)
FEMA 2377 | DIETHYL SUCCINATE
refractive index n20/D 1.42(lit.)
Flash point 195 °F
storage temp. Store below +30°C.
solubility 2.00g/l
form Liquid
color Clear colorless to yellow
Odor at 100.00 %. mild fruity cooked apple ylang
Odor Type fruity
biological source synthetic
Viscosity 2.685mm2/s
Water Solubility Slightly soluble in water.
JECFA Number 617
Merck 14,8869
BRN 907645
Dielectric constant 6.6(30℃)
LogP 1.4 at 40℃
CAS DataBase Reference 123-25-1(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) DIETHYL SUCCINATE
FDA 21 CFR 172.515
EWG's Food Scores 1
FDA UNII ELP55C13DR
NIST Chemistry Reference Diethyl succinate(123-25-1)
EPA Substance Registry System Butanedioic acid, 1,4-diethyl ester (123-25-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H227
Precautionary statements  P210e-P280a-P370+P378a-P403+P235-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25-22-S24/25
WGK Germany  2
RTECS  WM7400000
TSCA  Yes
HS Code  29171990
Toxicity LD50 orally in Rabbit: 8530 mg/kg LD50 dermal Rat > 5000 mg/kg
NFPA 704
1
0

Diethyl succinate price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 1 unit $59.6 2025-07-31 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 1 unit $59.6 2025-07-31 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 100g $63.5 2025-07-31 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 1kg $215 2025-07-31 Buy
Sigma-Aldrich W237712 Diethyl succinate natural, ≥99%, FG 123-25-1 5kg $953 2025-07-31 Buy
Product number Packaging Price Buy
W237712 1 unit $59.6 Buy
W237712 1 unit $59.6 Buy
W237712 100g $63.5 Buy
W237712 1kg $215 Buy
W237712 5kg $953 Buy

Diethyl succinate Chemical Properties,Uses,Production

Description

Diethyl succinate is obtained by the direct esterification of a carboxylic acid and an alcohol in the presence of concentrated H2SO4 in benzene solution. It has a faint, pleasant odor. It occurs naturally in apple, raspberry, cognac, rum, whiskey, cider, sherry, plum brandy, apple brandy, grape brandy, cherry brandy, cocoa, arrack and red, white, port, strawberry and sparking wines.
It is used as a flavor agent in foods including nonalcoholic/alcoholic beverages, baked goods, frozen dairy, hard/soft candy, gelatins, and puddings.

References

[1] George A. Burdock (2016) Fenaroli’s Hanbook of Flavor Ingredients, Sixth Edition
[2] https://en.wikipedia.org/wiki/Diethyl_succinate

Chemical Properties

Diethyl succinate is the diethyl ester of succinate. It is a colorless liquid with a faint, pleasant odor. miscible with ethanol and ether, soluble in acetone, insoluble in water.

Occurrence

Reported found in apple, raspberry, cognac, rum, whiskey, cider, sherry, plum brandy, apple brandy, grape brandy, cherry brandy, cocoa, arrack and red, white, port, strawberry and sparkling wines.

Uses

Diethyl succinate can be used as solvent; food flavoring agent; organic synthesis intermediate; gas chromatography stationary solution (maximum use temperature 60°C, solvent is ether). Alkyl succinates have been used as ashless dispersants and detergent additives for lubricating oils.

Uses

Diethyl Succinate is a diester molecule present naturally in plant and animal tissues. Used commonly in fragrances and food flavourings.

Preparation

Diethyl succinate is synthesized by esterification of succinic acid and ethanol; by direct esterification of the acid in the presence of concentrated H2SO4 in benzene solution.

Definition

ChEBI: Diethyl succinate is a fatty acid ester.

Aroma threshold values

Aroma characteristics at 1.0%: fruity, waxy, floral and slightly musty.

Taste threshold values

Taste charReported found in apple, raspberry, cognac, rum, whiskey, cider, sherry, plum brandy, apple brandy, grape brandy, cherry brandy, cocoa, arrack and red, white, port, strawberry and sparkling wines. acteristics at 10 to 100 ppm: chemical earthy, fruity with a pulpy mouthfeel

Synthesis Reference(s)

The Journal of Organic Chemistry, 56, p. 6720, 1991 DOI: 10.1021/jo00023a047
Tetrahedron Letters, 28, p. 2393, 1987 DOI: 10.1016/S0040-4039(00)96133-1

General Description

Diethyl succinate(DES) is a diethyl ester with succinate molecules. It has two ester groups and is majorly used in fragrances. It produced by the esterification of succinic acid with ethanol.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Taste at 10-100 ppm

Safety Profile

Mildly toxic by ingestion. A skin and eye irritant. Combustible liquid. Reaction with ethyl trifluoroacetate + sodium hydride may cause a fire or explosion. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTERS.

Purification Methods

Dry the succinate with MgSO4, and distil it at 15mm pressure. [Beilstein 2 IV 1914.]

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View Lastest Price from Diethyl succinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diethyl succinate pictures 2025-09-30 Diethyl succinate
123-25-1
US $30.00 / mg 98.00% 10g TargetMol Chemicals Inc.
Diethyl succinate pictures 2025-09-29 Diethyl succinate
123-25-1
US $0.00 / KG 25KG 99%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Diethyl succinate pictures 2025-08-08 Diethyl succinate
123-25-1
US $50.00 / kg 1kg 99% 20tons Hebei Mujin Biotechnology Co.,Ltd
Clorius Diethyl ester of butanedioic acid Diethylester kyseliny jantarove diethylesterkyselinyjantarove Succinic Acid Diethyl Ester Ethyl Succinate DIETHYL SUCCINATE FOR SYNTHESIS Diethyl succinate, standard for GC,>=99.6%(GC) Diethyl succinate ReagentPlus(R), 99% Diethyl succinate Vetec(TM) reagent grade, 98% Diethyl succite Butanedioicacid, diethyl ester (9CI) ETHYL SUCCINATE FEMA 2377 DIETHYL SUCCINATE diethyl butanedioate BUTANEDIOIC ACID DIETHYL ESTER DIETHYL SUCCINATE 99+% FCC diethylsuccinate,diethylesterbutadienoicacid,diethylsuccinate,diethylbutanedioate Diethylsuccinat DIETHYL SUCCINATE, NATURAL Butanedioic acid, diethyl ester: (Succinic acid, diethyl ester) Succinic acid diethyl Diethyl succinate,99% SUCCINIC ACID DIETHYL ESTER AKOS BBS-00004411 Diethyl succinate >=99.0% 2,2-diethylbutanedioate Diethyl succinate(N) Diethyl succinate@1000 μg/mL in Hexane Diethyl Succinate with High Purity Butanedioic acid, 1,4-diethyl ester DIETHYL SUCCINATE 123-25-1 Diethyl succinate USP/EP/BP Diethyl succinate(kosher) Bifeprunox Impurity 25 Diethyl Succite 99% For Synthesis C16985300 SucciniCacid-diethyLester Diethyl succinate, 10 mM in DMSO Diethyl succinate, 98% diethyl succinate ethyl succinate Succinic acid diethyl ester Butanedioic acid diethyl ester 123-25-1 23-25-1 C2H5OCOCH2CH2COOC2H5 C2H5OCOCH22COOC2H5 C8 to C9 Carbonyl Compounds Building Blocks Analytical Standards Analytical Chromatography Product Catalog Plasticizer Fatty Acid Esters (Plasticizer) Esters Environmental Standards Chromatography Organic Building Blocks Volatiles/ Semivolatiles Alpha Sort D