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2-Nitrobenzoic acid

2-Nitrobenzoic acid structure

CAS No.: 552-16-9

Chemical Name:: 2-Nitrobenzoic acid

Synonyms: O-NITROBENZOIC ACID;2-nitrobenzoic;2-NITRODRACYLIC ACID;2-Nitrobenzoicacid,95%;Nitrobenzoic aci;2-nitro-benzoicaci;o-Nitrobenaoicacid;o-nitro-benzoicaci;RARECHEM AL BO 0202;ORTHO-NITROBENZOATE

CBNumber:: CB9853809

Molecular Formula:: C7H5NO4

Molecular Weight:: 167.12

MDL Number:: MFCD00007137

MOL File:: 552-16-9.mol

MSDS File:: SDS

Last updated:2025-12-05 14:33:18

Product description	Number	Pack Size	Price
2-Nitrobenzoic acid 95%, Contains 3- and 4-isomers	127698	5g	$52.7
2-Nitrobenzoic acid 95%, Contains 3- and 4-isomers	127698	100g	$160
2-Nitrobenzoic Acid >90.0%(GC)	N0155	25g	$44
2-Nitrobenzoic Acid >90.0%(GC)	N0155	500g	$460
2-Nitrobenzoic acid	N493515	10g	$60
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2-Nitrobenzoic acid Properties

Melting point	146-148 °C(lit.)
Boiling point	295.67°C (rough estimate)
Density	1,58 g/cm³
refractive index	1.6280 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	7.8g/l
form	Fine Powder
pka	2.16(at 18℃)
color	Off-white
Specific Gravity	1.58
Water Solubility	6.8 g/L
Merck	14,6588
BRN	1910632
Stability	Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference	552-16-9(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	S6S4653K7Z
NIST Chemistry Reference	Benzoic acid, 2-nitro-(552-16-9)
EPA Substance Registry System	o-Nitrobenzoic acid (552-16-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-68-22

Safety Statements

26-36/37/39

WGK Germany

RTECS

DH5050000

TSCA

TSCA listed

HS Code

29163900

NFPA 704

	0
2		0

2-Nitrobenzoic acid price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	127698	2-Nitrobenzoic acid 95%, Contains 3- and 4-isomers	552-16-9	5g	$52.7	2025-07-31	Buy
Sigma-Aldrich	127698	2-Nitrobenzoic acid 95%, Contains 3- and 4-isomers	552-16-9	100g	$160	2025-07-31	Buy
TCI Chemical	N0155	2-Nitrobenzoic Acid >90.0%(GC)	552-16-9	25g	$44	2025-07-31	Buy
TCI Chemical	N0155	2-Nitrobenzoic Acid >90.0%(GC)	552-16-9	500g	$460	2025-07-31	Buy
TRC	N493515	2-Nitrobenzoic acid	552-16-9	10g	$60	2021-12-16	Buy

Product number	Packaging	Price	Buy
127698	5g	$52.7	Buy
127698	100g	$160	Buy
N0155	25g	$44	Buy
N0155	500g	$460	Buy
N493515	10g	$60	Buy

2-Nitrobenzoic acid Chemical Properties,Uses,Production

Chemical Properties

off-white powder

Uses

NH2-protecting reagent.

Uses

2-Nitrobenzoic Acid is used as a reagent in the synthesis of several organic compounds including that of novel triazoles and a tetrazole of escitalopram which act as cholinesterase inhibitors. It is also used in the one pot synthesis of 1,4-disubstituted 1,2,3-triazoles.

Definition

ChEBI: A nitrobenzoic acid carrying the nitro substituent at position 2.

Synthesis Reference(s)

The Journal of Organic Chemistry, 56, p. 5924, 1991 DOI: 10.1021/jo00020a040
Tetrahedron Letters, 35, p. 219, 1994 DOI: 10.1016/S0040-4039(00)76515-4

General Description

Yellowish white crystals with an intensely sweet taste.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Nitrobenzoic acid is incompatible with strong oxidizing agents. Also incompatible with strong bases. May react with cyanides .

Health Hazard

ACUTE/CHRONIC HAZARDS: When 2-Nitrobenzoic acid is heated to decomposition it emits very toxic fumes.

Fire Hazard

Flash point data concerning 2-Nitrobenzoic acid are not available, however, 2-Nitrobenzoic acid is probably combustible.

Purification Methods

Crystallise the acid from *benzene (twice), n-butyl ether (twice), then water (twice). Dry and store it in a vacuum desiccator. [Le Noble & Wheland J Am Chem Soc 80 5397 1958.] It has also been crystallised from EtOH/H2O. The amide has m 176.5o (from H2O). [Beilstein 9 III 1466, 9 IV 1046.]

2-Nitrobenzoic acid Preparation Products And Raw materials

Raw materials

2-Nitrotoluene

Preparation Products

Methyl anthranilate 2-Nitrobenzoyl chloride Fomesafen Benzoic acid, 2-nitro-, 1,1'-anhydride N-(2-AMINO-4-CHLOROPHENYL)ANTHRANILIC ACID

1,2-DIHYDRO-4-HYDROXY-2-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 2-NITROPHENYL ISOCYANATE 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID METHYL 2-NITROBENZOATE 2,5-diaminobenzoic acid

2,2'-DINITRODIBENZYL 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID

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2-Nitrobenzoic acid Suppliers

Global( 477)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8757	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5244	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20130	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21604	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29843	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2161	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
Xiamen AmoyChem Co., Ltd	58

View Lastest Price from 2-Nitrobenzoic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-29	2-Nitrobenzoic acid 552-16-9	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-12-22	2-Nitrobenzoic acid 552-16-9	US $29.00 / mL		99.97%	10g	TargetMol Chemicals Inc.
2025-09-25	2-Nitrobenzoic acid 552-16-9	US $100.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

2-Nitrobenzoic acid
552-16-9
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Nitrobenzoic acid
552-16-9
US $29.00 / mL
99.97%
TargetMol Chemicals Inc.

2-Nitrobenzoic acid
552-16-9
US $100.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

2-Nitrobenzoic acid Spectrum

2-Nitrobenzoic acid(552-16-9)MS 2-Nitrobenzoic acid(552-16-9)¹HNMR 2-Nitrobenzoic acid(552-16-9)¹³CNMR 2-Nitrobenzoic acid(552-16-9)IR1 2-Nitrobenzoic acid(552-16-9)IR2 2-Nitrobenzoic acid(552-16-9)Raman

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2-NITRODRACYLIC ACID RARECHEM AL BO 0202 O-NITROBENZOIC ACID OTAVA-BB BB0125160260 O-NITROBENZOIC ACID APPROX. 95% 2-Nitrobenzoicacid,95% 2-nitrobenzoic 2-nitro-benzoicaci LABOTEST-BB LT00853998 Benzoic acid, o-nitro- 2-Nitrobenzoic acid, 85-90% 2-Nitrobenzoic acid ,98% ORTHO-NITROBENZOATE ORTHO-NITROBENZOICACID Benzoicacid,2-nitro- o-carboxynitrobenzene o-Nitrobenaoicacid o-nitro-benzoicaci 1-CARBOXY-2-NITROBENZENE 2-NITROBENZOIC ACID 2-Nitrobenzoic acid, synthesis grade Nitrobenzoic aci 2-Nitrobenzoic acid 95%, Contains 3- and 4-isoMers Adjacent nitro benzoic acid 2-Nitrobenzoic acid Vetec(TM) reagent grade, 94% 2-NitrobenzoicAcid> 2-Nitrobenzoic acid ISO 9001：2015 REACH TIANFUCHEM--552-16-9--High purity 2-Nitrobenzoic acid factory price 2-Nitrobenzoic Acid， ≥ 95.0% 2-Nitrobenzoic acid, 10 mM in DMSO 2-Nitrobenzoic acid - Technical 552-16-9 NO2C6H4COOH O2NC6H4CO2H Organic Building Blocks CARBOXYLIC ACID Reagents for Oligosaccharide Synthesis Building Blocks Carbonyl Compounds Carboxylic Acids C7 Pharmaceutical Intermediates Pyridines Building Blocks Carbonyl Compounds Carboxylic Acids Chemical Synthesis Organic Building Blocks carboxylic acid| nitro-compound Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Biochemistry Reagents for Oligosaccharide Synthesis C7 Carbonyl Compounds Carboxylic Acids