ChemicalBook >> CAS DataBase List >>Palmitic acid ethyl ester

Palmitic acid ethyl ester

CAS No.
628-97-7
Chemical Name:
Palmitic acid ethyl ester
Synonyms
ETHYL PALMITATE;ETHYL HEXADECANOATE;HEXADECANOIC ACID ETHYL ESTER;Hexadecanoic acid ethyl;FEMA 2451;Ethyl palmita;Ethyl Hexadecanoate(C16:0);NSC 8918;Palmitic aci;Sixteen ethyl
CBNumber:
CB9854033
Molecular Formula:
C18H36O2
Molecular Weight:
284.48
MDL Number:
MFCD00008996
MOL File:
628-97-7.mol
MSDS File:
SDS
Last updated:2026-04-03 14:17:14
Product description Number Pack Size Price
Ethyl palmitate ≥95%, FG W245100 1 each $58
Ethyl Palmitate ≥95%, FG W245100 1kg $301
Ethyl Palmitate natural (US), ≥95%, FG W245115 1kg $409
Ethyl Palmitate ≥95%, FG W245100 5kg $511
Ethyl Palmitate ≥95%, FG W245100 10Kg $844
More product size

Palmitic acid ethyl ester Properties

Melting point 24-26 °C (lit.)
Boiling point 192-193 °C/10 mmHg (lit.)
Density 0.857 g/mL at 25 °C (lit.)
vapor pressure 0.01Pa at 25℃
refractive index n20/D 1.440(lit.)
FEMA 2451 | ETHYL PALMITATE
FLAVIS Number 09.193 | Ethyl hexadecanoate
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form <24°C Solid,>26°C Liquid
color Colourless to Off-White
Specific Gravity 0.857
Odor at 100.00 %. mild waxy fruity creamy milky balsamic greasy oily
Odor Type waxy
biological source synthetic
Water Solubility IMMISCIBLE
JECFA Number 39
BRN 1782663
Dielectric constant 2.7(103℃)
Major Application cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
Cosmetics Ingredients Functions PERFUMING
SKIN CONDITIONING - EMOLLIENT
InChI 1S/C18H36O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20-4-2/h3-17H2,1-2H3
InChIKey XIRNKXNNONJFQO-UHFFFAOYSA-N
SMILES CCCCCCCCCCCCCCCC(=O)OCC
LogP 7.74
CAS DataBase Reference 628-97-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) ETHYL PALMITATE
EWG's Food Scores 1
FDA UNII IRD3M534ZM
NIST Chemistry Reference Hexadecanoic acid, ethyl ester(628-97-7)
EPA Substance Registry System Hexadecanoic acid, ethyl ester (628-97-7)
UNSPSC Code 85151701
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS08
Signal word  Danger
Hazard statements  H413
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Hazard Codes  Xi
Safety Statements  23-24/25
WGK Germany  3
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29157020
Storage Class 10 - Combustible liquids
NFPA 704
0
0 0

Palmitic acid ethyl ester price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W245100 Ethyl palmitate ≥95%, FG 628-97-7 1 each $58 2026-03-19 Buy
Sigma-Aldrich W245100 Ethyl Palmitate ≥95%, FG 628-97-7 1kg $301 2026-03-19 Buy
Sigma-Aldrich W245115 Ethyl Palmitate natural (US), ≥95%, FG 628-97-7 1kg $409 2026-03-19 Buy
Sigma-Aldrich W245100 Ethyl Palmitate ≥95%, FG 628-97-7 5kg $511 2026-03-19 Buy
Sigma-Aldrich W245100 Ethyl Palmitate ≥95%, FG 628-97-7 10Kg $844 2026-03-19 Buy
Product number Packaging Price Buy
W245100 1 each $58 Buy
W245100 1kg $301 Buy
W245115 1kg $409 Buy
W245100 5kg $511 Buy
W245100 10Kg $844 Buy

Palmitic acid ethyl ester Chemical Properties,Uses,Production

Description

Palmitic acid ethyl ester, also known as ethyl palmitate, it the ethyl ester form of palmitic acid. It can be used as a hair- and skin-conditioning agent. It has been shown that the combination between palmitic acid ethyl ester and cobra venom factor can enhance the survival of heterologous erythrocyte. Recent study has also demonstrated the potential anti-inflammatory activity of palmitic acid ethyl ester in several animal models.

Chemical Properties

clear colorless oily liquid after melting

Chemical Properties

Ethyl palmitate has a mild, waxy sweet odor. It is nearly tasteless and has a creamy mouthfeel.

Occurrence

Reported found in mutton, rye bread, rice, bourbon, vanilla, red sage, lemon balm, bilberry, Parmesan cheese, maple syrup, Jamaican rum, whiskey, grape wine, cognac, cocoa, green tea, mango, corn oil and mastic gum leaf oil.

Uses

Ethyl palmitate acts as a lubricant on the skins surfaces in order to get a soft and smooth appearance. It increases cytosolic Ca2+ concentration leading to pancreatic acinar cell injury due to excessive consumption of ethanol.

Uses

A fatty acid found in Amaranth oil; it shows inhibitory activity.

Definition

ChEBI: Ethyl hexadecanoate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of ethanol. It has a role as a plant metabolite. It is a hexadecanoate ester and a long-chain fatty acid ethyl ester.

Aroma threshold values

Detection: 2 ppm

Taste threshold values

Taste characteristics at 30 ppm: waxy, fruity, creamy and fermented with a vanilla, balsamic nuance.

Synthesis Reference(s)

Tetrahedron, 48, p. 8775, 1992 DOI: 10.1016/S0040-4020(01)89450-3

General Description

Ethyl palmitate is a one of the major volatile compounds found in cooked rice and Luzhou-flavor raw liquor. It occurs naturally in licorice root and chamomile.

Safety

Palmitic acid ethyl ester, also known as Ethyl palmitate, is a versatile aromatic ester compound widely used as a food additive, fragrance ingredient and cosmetic emollient. Due to the lack of conclusive animal or human evidence, the substance is not classified as "harmful by ingestion". After ingestion, the substance may still harm personal health, especially if there is already significant damage to organs (such as liver, kidneys). Gastrointestinal discomfort may cause nausea and vomiting. However, in an occupational environment, unintentional ingestion is not considered a cause for concern. The Cosmetic Ingredient Safety Panel has evaluated the safety of palmitic acid esters. The panel evaluated the scientific data and concluded that ethylhexyl palmitate, cetyl palmitate and isopropyl palmitate are safe as cosmetic ingredients.

Synthesis

Synthesized by immobilized lipase-catalyzed alcoholysis and esterification in organic solvents.

References

Beste, Russell D, and R. D. Hamlin. "Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate." US, US6267984. 2001.
Castro, O, et al. "Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival. " Proceedings of the Society for Experimental Biology & Medicine Society for Experimental Biology & Medicine 147.1(1974):106.
Saeed, N. M., et al. "Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. " Toxicology & Applied Pharmacology 264.1(2012):84-93.

64-17-5
57-10-3
628-97-7
Synthesis of Palmitic acid ethyl ester from Ethanol and Palmitic acid

Palmitic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 496)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21592 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29822 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 1497 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58

Related articles

View Lastest Price from Palmitic acid ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl Palmitate pictures 2026-04-20 Ethyl Palmitate
628-97-7
US $0.00 / Kg/Drum 180KG 99%min 150tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Palmitic acid ethyl ester pictures 2026-03-20 Palmitic acid ethyl ester
628-97-7
US $10.00 / KG 1KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
Palmitic acid ethyl ester pictures 2025-09-25 Palmitic acid ethyl ester
628-97-7
US $35.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • Ethyl Palmitate pictures
  • Ethyl Palmitate
    628-97-7
  • US $0.00 / Kg/Drum
  • 99%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
Ethyl palmita HEXADECANOIC ACID ETHYL ESTER Ethyl cetylate ETHYL HEXADECANOATE ETHYL PALMITATE ETHYL N-HEXADECANOATE FEMA 2451 Ethyl palmitate, (Ethyl hexadecanoate Palmitic aci FATTY ALCOHOLS ETHOXYLATED ETHYL PALMITATE 95+% Ethylpalmitate,97% Hexadecanoic acid ethyl Palmitic acid ethyl ETHYL PALMITATE, NATURAL Ethyl palmitate,98% Ethyl palmitate,Ethyl hexadecanoate, Palmitic acid ethyl ester Ethyl hexadecylate Sixteen ethyl NSC 8918 Ethyl palMitat ETHYL PALMITATE(P) PALMITIC ACID ETHYL ESTER 628-97-7PalMitic acid ethyl ester Hexadecanoic a Ethyl palmitate Vetec(TM) reagent grade, 95% Ethyl Hexadecanoate(C16:0) EthylPalmitate> Ethyl palmitate@10 mg/mL in Hexane ETHYL PALMITATE FOR SYNTHESIS Palmitic acid ethyl ester USP/EP/BP Ethyl palmitate(kosher) Factory supply Palmitic acid ethyl ester/Ethyl palmitate with good price CAS 628-97-7 CAS 628-97-7 Palmitic acid ethyl ester HEXADECANOIC ETHYL Ethyl palmitate in acetonitrile Ethyl palmitate in isooctane Ethyl palmitate-d5 in acetonitrile Ethyl palmitate, 1mg/ml in Acetonitrile Ethyl hexadecanoate(Ethyl palmitate) 628-97-7 CH3CH214CO2CH2CH3 C15H31COOC2H5 CH3CH214COOC2H5 Carbonyl Compounds C12 to C63 Building Blocks Biochemicals and Reagents BioChemical Esters Saturated fatty acids and derivatives Lipids Organic Building Blocks Ethyl Ester Fatty Acids Fatty Acid Derivatives & Lipids Glycerols Inhibitors