S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT
- CAS No.
- 78950-78-4
- Chemical Name:
- S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT
- Synonyms
- 3-(dipropylamino)tetralin-5-ol;7-(dipropylamino)tetralin-1-ol;2-(Dipropylamino)tetralin-8-ol;8-OH-DPAT (8-Hydroxy-DPAT) ，S8447;8-Hydroxy-2-(di-n-propylamino)tetralin;S(-)-8-Hydroxy-DPAT hydrobromide solid;S(-)-8-HYDROXY-DPATHYDROBROMIDEPARTIAL5-HT1A;7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol;5,6,7,8-Tetrahydro-7-(dipropylamino)naphthalen-1-ol;(+/-)-8-Hydroxy-2-dipropylaminotetralinehydrobromide
- CBNumber:
- CB9972175
- Molecular Formula:
- C16H25NO
- Molecular Weight:
- 247.38
- MDL Number:
- MFCD00870476
- MOL File:
- 78950-78-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| S(?)-8-Hydroxy-DPAT hydrobromide solid | H141 | 5mg | $129 |
| S(?)-8-Hydroxy-DPAT hydrobromide solid | H141 | 25mg | $426 |
| 8-OH-DPAT | BO166474 | 5mg | $250 |
| 8-OH-DPAT | BO166474 | 10mg | $344.1 |
| 8-OH-DPAT | BO166474 | 25mg | $688.25 |
| More product size | |||
| Boiling point | 372.5±42.0 °C(Predicted) |
|---|---|
| Density | 1.03±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | 150mg/ml in DMSO |
| form | solid |
| pka | 10.54±0.40(Predicted) |
| color | white |
| optical activity | [α]25/D 67.8° in methanol(lit.) |
| InChI | 1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m0./s1 |
| InChIKey | BATPBOZTBNNDLN-UQKRIMTDSA-N |
| SMILES | Br.CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 |
| FDA UNII | IWS1724PX6 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H141 | S(?)-8-Hydroxy-DPAT hydrobromide solid | 78950-78-4 | 5mg | $129 | 2022-05-15 | Buy |
| Sigma-Aldrich | H141 | S(?)-8-Hydroxy-DPAT hydrobromide solid | 78950-78-4 | 25mg | $426 | 2022-05-15 | Buy |
| Biosynth | BO166474 | 8-OH-DPAT | 78950-78-4 | 5mg | $250 | 2026-06-04 | Buy |
| Biosynth | BO166474 | 8-OH-DPAT | 78950-78-4 | 10mg | $344.1 | 2026-06-04 | Buy |
| Biosynth | BO166474 | 8-OH-DPAT | 78950-78-4 | 25mg | $688.25 | 2026-06-04 | Buy |
S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT Chemical Properties,Uses,Production
Uses
8-OH-DPAT, is a potent and selective 5-HT agonist.
Definition
ChEBI: A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Hazard
A poison.
Biochem/physiol Actions
Partial 5-HT1A serotonin receptor agonist.
in vivo
8-OH-DPAT (1 mg/kg) normalizes hypolocomotion, significantly increases wakefulness and reduces the duration of REM sleep without effect on the duration of non-REM sleep in the dark period in orexin knockout (KO) mice. 8-OH-DPAT shows no obvious effect on wakefulness or the duration of either REM sleep or non-REM sleep in WT mice. 8-OH-DPAT (1 mg/kg, s.c.) activates 5-HT1A receptor in orexin knockout mice[3].
IC 50
5-HT1A Receptor: 8.19 (pIC50); 5-HT7 Receptor: 466 nM (Ki)
S(-)-8-HYDROXY-DPAT HYDROBROMIDE PARTIAL 5-HT1A SECROT Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 5932 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33324 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +86-0086-13720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
