2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE 物理性質
- 融点 :
- 151-156 °C
- 沸点 :
- 672.4±55.0 °C(Predicted)
- 比重(密度) :
- 1.22
- 貯蔵温度 :
- Sealed in dry,Store in freezer, under -20°C
- 酸解離定数(Pka):
- 11.87±0.70(Predicted)
- 外見 :
- Solid
- 色:
- White to off-white
- 水溶解度 :
- CHCl3 に可溶。水に不溶。
- InChIKey:
- OGOMAWHSXRDAKZ-DLANKZEINA-N
- SMILES:
- O([C@@H]1[C@H]([C@@H](O)O[C@H](COCC2C=CC=CC=2)[C@H]1OCC1C=CC=CC=1)OCC1C=CC=CC=1)CC1C=CC=CC=1 |&1:1,2,3,6,16,r|
- LogP:
- 5.9 at 20℃ and pH6.5
- CAS データベース:
- 6564-72-3(CAS DataBase Reference)
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE 価格
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2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE 化学特性,用途語,生産方法
説明
2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU.
Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form.
Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.
使用
It is the intermediate of Voglibose/Dapagliflozin. An important D-glucopyranose derivative for glucosylations and other reactions 1,2; Preparation of the α-glucopyranosyl chloride, synthesis of 1-C-α-D-glucopyranose derivatives.
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE 上流と下流の製品情報
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2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE 生産企業
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6564-72-3()キーワード:
4-アミノ-3,4-ジデオキシ-2-C-(ヒドロキシメチル)-D-epi-イノシトール
エチル2,3,4,6-テトラ-O-アセチル-1-チオ-Β-D-グルコピラノシド
メチルβ-D-リボフラノシド
イソチオシアン酸2,3,4,6-テトラ-O-アセチル-β-D-グルコピラノシル
FMOC-THR(GALNAC(AC)3-Α-D)-OH
D-(+)-ガラクトース (無水)
2,3,4,6-テトラ-O-アセチル-α-D-グルコピラノシルブロミド
1-ブロモ-2-O,3-O,4-O,6-O-テトラアセチル-1-デオキシ-α-D-ガラクトピラノース
2,3,4,6-テトラ-O-ベンジル-D-グルコピラノース
ボグリボース
- 6564-72-3
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose (for Voglibose)
- Voglibose int
- Voglibose Impurity 1
- 2,3,4,6-Tetra-O-benzyl-D-glycopyranose
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSIDE
- 2,3,4,6-TETRA-O-BENZOYL-D-GLUCOPYRANOSE
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose
- benzylglucopyranose
- 6-Tetra-O-benzyl-D-glucopyranose
- 2,3,4,6-tetra-o-benzyl-d-glucose
- 2,3,4,6-Tetra-o-benzyl-D-glucopyransoe
- 2,3,4,6-Tetra-O-benzyl-a-D-glucopyranose
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE ,GB
- 2,3,4,6-TETRA-O-ACETYL A-D-GLUCOPYRANOSIDE
- 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranos
- alpha-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylMethyl)-
- a-D-Glucopyranose,2,3,4,6-tetrakis-O-(phenylMethyl)-
- Voglibose TBG IMpurity
- (2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)Methyl)tetrahydro-2H-pyran-2-ol
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose SynonyMs 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose
- 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose
2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose
- Voglibose TBG impurities
- Voglibose alpha-TBG Impurity
- 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose
- 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOSE 6564-72-3
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE USP/EP/BP
- 2,3,4,6-TETRA-O-BENZYL-ALPHA GLUCOPYRANOSE（COM）
- 2,3,4,6-TETRA-O-BENZYL-D-GLUCChemicalbookOPYRANOSE
- 2,3,4,6-Tetra-O-benzyl-D-glucopyranose(TBG)
- 2,3,4,6-Tetrakis-O-(phenylmethyl)-α-D-glucopyranose