11-DEOXY-11-METHYLENE PROSTAGLANDIN D2

 化学構造式
100648-29-1
CAS番号.
100648-29-1
化学名:
别名:
英語名:
11-DEOXY-11-METHYLENE PROSTAGLANDIN D2
英語别名:
11-Deoxy-11-methylene PGD2;ROZAFJXVUNORLT-SFIVEXQWSA-N;11-DEOXY-11-METHYLENE PROSTAGLANDIN D2;11-deoxy-11-methylene Prostaglandin D2;9ALPHA,15S-DIHYDROXY-11-METHYLENE-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oicacid,9,15-dihydroxy-11-methylene-,(5z,9a,13e,15s)-;Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-methylene-, (5Z,9α,13E,15S)-
CBNumber:
CB0448473
化学式:
C21H34O4
分子量:
350.49
MOL File:
100648-29-1.mol

11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 物理性質

溶解性:
DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 3.75 mg/ml

安全性情報

11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 化学特性,用途語,生産方法

使用

Prostaglandin D2 (PGD2; ) is one of the five primary enzymatic prostaglandins derived directly from PGH2 . PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, leukocyte-type PGD synthase. 11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin. However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets, a DP1 receptor assay.

11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 上流と下流の製品情報

原材料

準備製品


11-DEOXY-11-METHYLENE PROSTAGLANDIN D2 生産企業

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  • 100648-29-1
  • 9ALPHA,15S-DIHYDROXY-11-METHYLENE-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • 11-deoxy-11-methylene Prostaglandin D2
  • ROZAFJXVUNORLT-SFIVEXQWSA-N
  • 11-DEOXY-11-METHYLENE PROSTAGLANDIN D2
  • Prosta-5,13-dien-1-oic acid, 9,15-dihydroxy-11-methylene-, (5Z,9α,13E,15S)-
  • Prosta-5,13-dien-1-oicacid,9,15-dihydroxy-11-methylene-,(5z,9a,13e,15s)-
  • 11-Deoxy-11-methylene PGD2
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