Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-

1332881-26-1

CAS番号.: 1332881-26-1

化学名:

别名:: サビザブリン

英語名:: Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-

英語别名:: Sabizabulin;ABI-231;sabizabulin(VERU-111);Sabizabulin/VERU-111/ABI-231;Sabizabulin (Synonyms: VERU-111;2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-Methanone;Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-;VERU-111 (1H-indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl)methanone

CBNumber:: CB05569748

化学式:: C21H19N3O4

分子量:: 377.39

MOL File:: 1332881-26-1.mol

物理性質

安全性情報

用途語

生産企業 49

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- 物理性質

沸点 :: 688.1±55.0 °C(Predicted)

比重(密度) :: 1.306±0.06 g/cm3(Predicted)

貯蔵温度 :: 4°C, away from moisture and light

溶解性:: Soluble in DMSO

酸解離定数(Pka):: 10.82±0.10(Predicted)

外見 :: Solid

色:: Light yellow to yellow

InChI:: InChI=1S/C21H19N3O4/c1-26-17-8-12(9-18(27-2)20(17)28-3)19(25)16-11-23-21(24-16)14-10-22-15-7-5-4-6-13(14)15/h4-11,22H,1-3H3,(H,23,24)

InChIKey:: WQGVHOVEXMOLOK-UHFFFAOYSA-N

SMILES:: C(C1NC(C2C3=C(NC=2)C=CC=C3)=NC=1)(C1=CC(OC)=C(OC)C(OC)=C1)=O

安全性情報

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- 化学特性,用途語,生産方法

効能

抗悪性腫瘍薬, 微小管重合阻害薬

説明

Sabizabulin (VERU-111) is a potent, orally bioavailable, and well-tolerated microtubule inhibitor that Veru Inc. is currently developing. It can inhibit the growth of ovarian tumors and completely suppress tumor metastasis in vivo, with efficacy comparable to that of paclitaxel, the current first-line treatment for ovarian cancer. VERU-111 can block the polymerization of tubulin and is not a substrate for multi-drug resistance mechanisms.

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- 上流と下流の製品情報

原材料

準備製品

Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)- 生産企業

Global( 49)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Sichuan Yiyan Pharmaceutical Research	19949968070; 19949968070	2904199885@qq.com	China	922	58
Taizhou Nanfeng Pharmaceutical Research Institute	nanfengpharma@126.co 18616377689	nanfengpharma@126.com	China	20008	58
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3493	58
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Biolang biotechnology Co.,Ltd	17764003753	2326587775@qq.com	China	185	55
Shanghai Biolang biotechnology Co.,Ltd	17764003753	2326587775@qq.com	China	185	55
Fan De(Beijing) Biotechnology Co., Ltd.	15911056312	liming@bio-fount.com	China	9718	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471	sales@sarms4muscle.com	China	10378	58

1332881-26-1()キーワード:

オンブラブリン塩酸塩

1332881-26-1
Methanone, [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-
ABI-231
Sabizabulin (Synonyms: VERU-111
sabizabulin(VERU-111)
VERU-111 (1H-indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl)methanone
2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)-Methanone
Sabizabulin/VERU-111/ABI-231
Sabizabulin
サビザブリン