ウリジントリアセタート

ウリジントリアセタート 価格 もっと(17)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01COBST-8291	2',3',5'-トリアセチルウリジン 2',3',5'-Triacetyluridine	4105-38-8	5g	￥10000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01COBST-8291	2',3',5'-トリアセチルウリジン 2',3',5'-Triacetyluridine	4105-38-8	1g	￥10000	2023-06-01	購入
東京化成工業	T2549	2',3',5'-トリ-O-アセチルウリジン >98.0%(HPLC)(T) 2',3',5'-Tri-O-acetyluridine >98.0%(HPLC)(T)	4105-38-8	5g	￥3100	2024-03-01	購入
東京化成工業	T2549	2',3',5'-トリ-O-アセチルウリジン >98.0%(HPLC)(T) 2',3',5'-Tri-O-acetyluridine >98.0%(HPLC)(T)	4105-38-8	25g	￥10100	2024-03-01	購入
Sigma-Aldrich Japan	SAB1306711	IgG fraction of antiserum, buffered aqueous solution ANTI-TAU(C-TERMINAL) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution	4105-38-8	400μL	￥89100	2024-03-01	購入

ウリジントリアセタート 化学特性,用途語,生産方法

外観

白色～ほとんど白色粉末～結晶

効能

解毒薬 (5-フルオロウラシル)

説明

Uridine triacetate is an orally available pro-drug of uridine approved by the FDA for the treatment of the rare autosomal recessive disorder called hereditary orotic aciduria. The drug was also approved for treating overdose of two chemotherapies (fluorouracil and capecitabine). Uridine triacetate was developed by Wellstat Therapeutics and licensed to BTG.

化学的特性

White or almost white crystalline powder

使用

2’,3’,5’-Triacetyluridine is used in the treatment of Alzheimer’s disease in mice and provide neuroprotective effects. Shown to also decrease depressive symptoms and increases in brain pH bipolar patients.

定義

ChEBI: Uridine triacetate is an acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. It has a role as a prodrug, a neuroprotective agent and an orphan drug. It is a member of uridines and an acetate ester.

参考文献

[1] E.D. Gudio, M.L. Ferreira, L.E. Iglesias . “A rational approach to the regioselective deacetylation of 2′,3′,5′-tri-O-acetyluridine by Novozym 435 catalysed alcoholysis.” Biochimica et biophysica acta. Proteins and proteomics 1824 4 (2012): Pages 627-636.
[2] Osama M Ashour . “Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2′,3′,5′-tri-O-acetyluridine, a prodrug of uridine.” Biochemical pharmacology 60 3 (2000): Pages 427-431.

ウリジントリアセタート 上流と下流の製品情報

原材料

準備製品

ウリジントリアセタート 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +86-18055311600	sales1@nuowei-chem.com	China	1627	58
Hangzhou Measure Life Technology Co., LTD	+8613343730176	2924244016@qq.com	China	83	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39927	58
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12580	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29733	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	12887	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21622	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58

4105-38-8(ウリジントリアセタート)キーワード:

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• 4105-38-8
• RG 2133
• Tri-O-acetyl uridine
• Uridine triacetate
• Vistonuridine
• 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
• 2',3',5'-Tri-O-acetyl-rU
• (2R,3R,4R,5R)-2-(AcetoxyMethyl)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
• 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyrimid
• ANTI-TAU(C-TERMINAL) antibody produced in rabbit
• MAPTL
• Microtubule-associated protein tau
• MTBT1
• ANTI-TAU (MAPT) (S720) antibody produced in rabbit
• [4-acetoxy-2-(acetoxymethyl)-5-(2,4-dioxopyrimidin-1-yl)tetrahydrofuran-3-yl] acetate
• [4-acetyloxy-2-(acetyloxymethyl)-5-(
• [4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate
• 2-(acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
• 2-[(acetyloxy)methyl]-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
• acetic acid [4-acetoxy-2-(acetoxymethyl)-5-(2,4-diketopyrimidin-1-yl)tetrahydrofuran-3-yl] ester
• acetic acid [4-acetoxy-2-(acetoxymethyl)-5-(2,4-dioxo-1-pyrimidinyl)-3-tetrahydrofuranyl] ester
• 1-((2R,3R,4R,5R)-3,4-Diacetyl-3,4-dihydroxy-5-(1-hydroxy-2-oxopropyl)tetrahydrofuran-2-yl)pyri
• (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4
• 2',3',5'-tri-O-Acetyluridine≥ 98% (HPLC)
• TAU
• URIDINE 2',3',5'-TRIACETATE
• 1-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-4-hydroxypyrimidine-2(1H)-one
• [(2R,3R,4R,5R)-4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate
• [(2R,3R,4R,5R)-4-acetyloxy-2-(acetyloxymethyl)-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] ethanoate
• acetic acid [(2R,3R,4R,5R)-4-acetoxy-2-(acetoxymethyl)-5-(2,4-diketopyrimidin-1-yl)tetrahydrofuran-3-yl] ester
• 2',3',5'-Tri-O-acety
• 1-(2-O,3-O,5-O-トリアセチル-β-D-リボフラノシル)ピリミジン-2,4(1H,3H)-ジオン
• ウリジン2',3',5'-トリアセタート
• 1-(2-O,3-O,5-O-トリアセチル-β-D-リボフラノシル)-4-ヒドロキシピリミジン-2(1H)-オン
• 2'-O,3'-O,5'-O-トリアセチルウリジン
• 2',3',5'-トリ-O-アセチルウリジン
• ウリジン 2',3',5'-トリアセタート
• 2',3',5'-トリアセチルウリジン
• ウリジントリアセタート
• ウリジン2′,3′,5′-トリアセタート
• [(2R,3R,4R,5R)-3,4-ビス(アセチルオキシ)-5-(2,4-ジオキソ-1,2,3,4-テトラヒドロピリミジン-1-イル)オキソラン-2-イル]メチル アセタート
• 2′-O,3′-O,5′-O-トリアセチルウリジン