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((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid

化学構造式
1132709-14-8
CAS番号.
1132709-14-8
化学名:
别名:
英語名:
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
英語别名:
2S)-Bortezomib;(1S,2S)-BortezoMib;Bortezomib (1S, 2S);Bortizomib SS-isomer;Bortezomib S,S Isomer;Bortezomib Impurity PS619;Bortezomib USP Impurity G;Bortezomib (1S,2S) isomer;(1S,2S)-Bortezomib Impurity;Bortezomib Diastereomer (S,S)
CBNumber:
CB12661930
化学式:
C19H25BN4O4
分子量:
384.24
MOL File:
1132709-14-8.mol

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 物理性質

比重(密度) :
1.214±0.06 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMSO : 50 mg/mL (130.13 mM; Need ultrasonic)
外見 :
Solid
酸解離定数(Pka):
9.66±0.43(Predicted)
色:
White to Off-White
安定性：:
Hygroscopic
InChIKey:
GXJABQQUPOEUTA-DOTOQJQBSA-N
SMILES:
B([C@H](NC(=O)[C@@H](NC(C1=NC=CN=C1)=O)CC1=CC=CC=C1)CC(C)C)(O)O

安全性情報

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 化学特性,用途語,生産方法

使用

(1S,2S)-Bortezomib is an isomer of Bortezomib (B675700), proteasome inhibitor. (1S,2S)-Bortezomib has been seen to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer’s or hypertension.

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 上流と下流の製品情報

原材料

準備製品

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 生産企業

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  スペクトルデータ(1HNMR)

((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid(1132709-14-8)1HNMR

1132709-14-8()キーワード:

抗ESR2抗体 ウサギ宿主抗体 3,7,11-トリメチル-1,3,6,10-ドデカテトラエン 15α-ヒドロキシエストリオール N-[(1S)-2-アミノ-2-オキソ-1-(フェニルメチル)エチル]-2-ピラジンカルボキサミド BORTEZOMIB (VELCADE) N-(ピラジニルカルボニル)-L-フェニルアラニン トリフルオロ酢酸(R)-ボロロイシン-(1S,2S,3R,5S)-(+)-ピナンジオールエステル
  • 1132709-14-8
  • ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid
  • Boronic acid, B-[(1S)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
  • (1S,2S)-BortezoMib
  • (1S,2S)-Bortezomib Impurity
  • [(1S)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2[(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid
  • Bortezomib Impurity PS619
  • N-(2-Pyrazinecarbonyl)-L-phenylalanine-D-leucine boronic anhydride
  • Bortezomib (1S,2S) Isomer Impurity
  • Bortezomib USP Impurity G
  • [(1S)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
  • Bortezomib impurity 3/(1S,2S)-Bortezomib
  • Bortezomib (1S, 2S)
  • Bortezomib (1S,2S) isomer
  • (1s) - 3-methyl-1 - [[(2S) - 1-oxo-3-phenyl-2 - [(pyrazinoformyl) - amino] propyl] amino] butyl] boric acid
  • Bortizomib SS-isomer
  • Bortezomib Related Compound G (Bortezomib S,S-Isomer Impurity)
  • Bortezomib Diastereomer (S,S)
  • ((R)-3-hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
  • 2S)-Bortezomib
  • ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)prop
  • Bortezomib S,S Isomer
  • 2-hydroxy-36-(methylthio)butanamide
  • (1S,2S)-Bortezomib, 10 mM in DMSO
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