ペムブロリズマブ(遺伝子組換え)
ペムブロリズマブ(遺伝子組換え) 物理性質
- 貯蔵温度 :
- Store at -80°C
- 外見 :
- Liquid
- 色:
- Colorless to light yellow
- CAS データベース:
- 1374853-91-4
ペムブロリズマブ(遺伝子組換え) 価格
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製品番号 |
製品説明 |
CAS番号 |
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ペムブロリズマブ(遺伝子組換え) 化学特性,用途語,生産方法
使用
A recombinant, single-chain, anti-CD19/anti-CD3 bispecific monoclonal antibody with potential immunostimulating and antineoplastic activities.
作用機序
Pembrolizumab is a humanized monoclonal IgG4 kappa antibody directed against human cell surface PD-1 (programmed death receptor-1) on lymphocytes. The PD-1 receptor provides a critical “immune checkpoint,” which helps prevent the immune system from attacking itself. Certain tumors have a high expression of PD-L1(programmed death receptor ligand-1). Other tumor types use adaptive immune resistance, which takes the natural physiology of PD-L1 induction (protection of immune-mediated damage from infections) and adapts it to anti-tumor responses. When PD-L1 engages with PD-1, the T-cell function becomes inhibited; pembrolizumab blocks the PD-1: PDL-1 complex formation, allowing improved T-cell mediated killing[1-2].
ペムブロリズマブ(遺伝子組換え) 上流と下流の製品情報
原材料
準備製品
ペムブロリズマブ(遺伝子組換え) 生産企業
Global( 114)Suppliers
1374853-91-4(ペムブロリズマブ(遺伝子組換え))キーワード:
- 1374853-91-4
- Lambrolizumab
- Pembrolizumab
- pembrolimumab
- Pembrolizumab (anti-PD-1)
- PEMBROLIMUMAB PD-1 1374853-91-4
- Pembrolizumab 25mg/ml
- PembrolizumabQ: What is
Pembrolizumab Q: What is the CAS Number of
Pembrolizumab Q: What is the storage condition of
Pembrolizumab Q: What are the applications of
Pembrolizumab
- Research Grade Pembrolizumab(DHH02202)
- MK-3475
- Research Grade Pembrolizumab
- Pembrolizumab - in storage buffer (ca 25 mg/ml)
- ペムブロリズマブ(遺伝子組換え)
- ペムブロリズマブ
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