4-tert-ブチルフェノール 化学特性,用途語,生産方法
外観
白色の結晶性粉末
溶解性
水に不溶。エタノール, ベンゼンに可溶。エタノール及びアセトンに溶けやすく、水にほとんど溶けない。
用途
合成樹脂変性(改質)剤、有機合成原料。
用途
環境試料中の内分泌攪乱物質の分析（HPLC）用標準品、GC-MS分析標準品。
用途
油溶性フェノール樹脂?農薬?紫外線吸収剤?界面活性剤原料
説明
Para-tertiary-butylphenol formaldehyde resin (PTBPF-
R) is a polycondensate of para-tertiary-butylphenol
and formaldehyde. Major occupational sources are
neoprene glues and adhesives in industry, in the
shoemaking and leather industry or in car production.
It is also used as a box preservative in box and
furniture manufacture, and in the production of
casting moulds, car-brake linings, insulated electrical
cables, adhesives, printing inks and paper laminates.
Para-tertiary-butyl-phenol is the sensitizer.
化学的特性
4-tert-Butylphenol is a white to pale yellow crystalline solid at room temperature and is sold in solid form as flakes or briquettes. 4-tert-butylphenol is employed in coating products, polymers, adhesives, sealants and for the synthesis of other substances.
The major use is as a monomer in chemical synthesis, e.g. for the production of polycarbonate, phenolic resins, epoxy resins. PtBP is used as a chain terminator in the synthesis of polycarbonate polymers. The main uses of polycarbonate are in compact discs, DVD and CD Rom manufacture.
天然物の起源
Reported found in origanum (Coridothymus cap. (L.) Richb.)
使用
4-tert-Butylphenol is a phenol derivative. Its contact with skin may lead to leukoderma. It is widely used in the polymer industry. Reaction of 4-tert-Butylphenol with mushroom tyrosinase has been reported to afford 4-t-butyl-o-benzoquinone and kinetics of this enzymatic reaction has been investigated.
主な応用
4-tert-Butylphenol may be employed as carbon and energy supplement in the culture medium of Sphingobium fuliginis strains.
4-tert-Butylphenol is suitable reagent used in kinetic study of hydroxylation of 4-tert-butylphenol by mushroom tyrosinase. It may be used in the synthesis of calix[7]arene.
製造方法
Prepared by heating phenol with isobutanol in the presence of zinc chloride; also from phenol, tert- butyl chloride and
excess alkali in alcohol
定義
ChEBI: 4-tert-butylphenol is a member of the class of phenols that is phenol substituted with a tert-butyl group at position 4. It has a role as an allergen.
一般的な説明
Crystals or practically white flakes. Has a disinfectant-like odor. May float or sink in water. Insoluble in water.
空気と水の反応
Insoluble in water.
反応プロフィール
Phenols, such as 4-tert-Butylphenol, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.
危険性
Irritant to eyes and skin.
火災危険
Combustible.
接触アレルゲン
Para-tert-butylphenol is used with formaldehyde to
produce the polycondensate p-tert-butylphenol-formaldehyde
resins (PTBPFR). Major occupational sources
are neoprene glues and adhesives in industry, in the
shoemaking and leather industries or in car production.
It is also used as a box preservative in box and furniture
manufacture and in the production of casting molds,
car brake linings, insulated electrical cables, adhesives,
printing inks, and paper laminates. Para-tertbutylphenol
seems to be the sensitizer
安全性プロファイル
Poison by
intraperitoneal route. Moderately toxic by
skin contact and ingestion. A skin and
severe eye irritant. Questionable carcinogen
with experimental neoplastigenic data.
Combustible when exposed to heat or
flame; can react with oxidizing materials. To
fight fire, use foam, CO2, dry chemical.
When heated to decomposition it emits
acrid and irritating fumes. See also
PHENOL and other butyl phenols.
職業ばく露
Butylphenols may be used as intermediates in manufacturing varnish and lacquer resins; as a
germicidal agent in detergent disinfectants; as a pour point
depressant, in motor-oil additives; de-emulsifier for oil;
soap-antioxidant, plasticizer, fumigant, and insecticide
輸送方法
UN2430 Alkylphenols, solid, n.o.s. (including
C2-C12 homologues), Hazard class: 8; Labels: 8—
Corrosive material
純化方法
Crystallise the phenol to constant melting point from pet ether (b 60-80o). It sublimes in vacuo. Also purify it via the benzoate, as for phenol. The salicylate ester [87-18-30] has m 63-64o (from aqueous EtOH, or EtOH). [Beilstein 6 IV 3296.]
不和合性
Vapors may form explosive mixture with
air. These phenol/cresol materials can react with oxidizers;
reaction may be violent. Incompatible with strong reducing
substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat
of the reaction may cause the gas to ignite and explode.
Heat is also generated by the acid-base reaction with bases;
such heating may initiate polymerization of the organic
compound. React with boranes, alkalies, aliphatic amines,
amides, nitric acid, sulfuric acid. Phenols are sulfonated
very readily (for example, by concentrated sulfuric acid at
room temperature). These reactions generate heat. Phenols
are also nitrated very rapidly, even by dilute nitric acid and
can explode when heated. Many phenols form metal salts
that may be detonated by mild shock
4-tert-ブチルフェノール 上流と下流の製品情報
原材料
準備製品