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BMS-345541

化学構造式
547757-23-3
CAS番号.
547757-23-3
化学名:
别名:
英語名:
BMS-345541
英語别名:
CS-1009;BMS-345541 HCl;BMS345541 (HCl Salt);BMS 345541 (HCl Salt);BMS345541 hydrochloride;BMS-345541 hydrochloride;BMS 345541 hydrochloride;BMS-345541 hydrochloride, 10 mM in DMSO;BMS345541 HYDROCHLORIDE; BMS-345541 HYDROCHLORIDE; BMS 345541 HYDROCHLORIDE;N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine hydrochloride
CBNumber:
CB2497314
化学式:
C14Cl1H18N5
分子量:
291.78
MOL File:
547757-23-3.mol
MSDS File:
SDS

BMS-345541 物理性質

貯蔵温度 :
2-8°C
溶解性:
DMSO: 18 mg/mL、可溶
外見 :
個体
色:
White to off-white
InChI:
1S/C14H17N5.ClH/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15;/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18);1H
InChIKey:
MIDKPVLYXNLFGZ-UHFFFAOYSA-N
SMILES:
Cl[H].Cc1ccc2nc(NCCN)c3ncc(C)n3c2c1

安全性情報

WGK Germany  3
ストレージクラス 11 - Combustible Solids

BMS-345541 価格 もっと(4)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC4806
BMS 345541 		547757-23-3 10mg ￥95000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC4806
BMS 345541 		547757-23-3 50mg ￥392000 2024-03-01 購入
Sigma-Aldrich Japan B9935 ≥98% (HPLC), powder
BMS-345541 ≥98% (HPLC), powder		 547757-23-3 5mg ￥46500 2024-03-01 購入
Sigma-Aldrich Japan B9935 ≥98% (HPLC), powder
BMS-345541 ≥98% (HPLC), powder		 547757-23-3 25mg ￥122000 2024-03-01 購入

BMS-345541 化学特性,用途語,生産方法

使用

BMS-345541 has been used:
  • as an IκB kinase (IKK) complex inhibitor to study its effects on the interferon-γ (IFN-γ) production by natural killer (NK) cells
  • as an IKK inhibitor to study its effects on the expression of eotaxin and monocyte chemoattractant protein-1 (MCP-1) mRNA in gingival fibroblasts
  • as nuclear factor κB (NF-κB) pathway inhibitor to study its effects on tumor necrosis factor α (TNFα) production in human oral squamous carcinomacells

Biochem/physiol Actions

BMS-345541 possesses anti-inflammatory properties. It also blocks the nuclear factor κB (NF-κB)-dependent transcription of pro-inflammatory cytokines. BMS-345541 possesses anti-inflammatory activity and plays a role in arresting bone erosion in certain animal models.

BMS-345541 上流と下流の製品情報

原材料

準備製品

BMS-345541 生産企業

Global( 89)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49979 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
 marketing@targetmol.com United States 32466 58
BOC Sciences 		16314854226; +16314854226
 inquiry@bocsci.com United States 19853 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc. 		+1-781-999-5354;
support@targetmol.com United States 39039 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Chembest Research Laboratories Limited 021-20908456
sales@BioChemBest.com China 6002 61

  スペクトルデータ(1HNMR)

BMS-345541(547757-23-3)1HNMR

547757-23-3()キーワード:

ブラネブルチニブ
  • 547757-23-3
  • BMS-345541 HCl
  • BMS345541 HYDROCHLORIDE; BMS-345541 HYDROCHLORIDE; BMS 345541 HYDROCHLORIDE
  • CS-1009
  • N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine hydrochloride
  • N-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine hydrochloride
  • BMS 345541 (HCl Salt)
  • BMS345541 (HCl Salt)
  • BMS 345541 hydrochloride
  • BMS345541 hydrochloride
  • BMS-345541 hydrochloride
  • N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine hydrochloride
  • I kappa B kinase,BMS345541 hydrochloride,Inhibitor,BMS345541,BMS-345541,BMS 345541,IKK,IκB kinase,BMS 345541 hydrochloride,inhibit
  • BMS-345541 hydrochloride, 10 mM in DMSO
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