Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	WH0010146M1	clone 2F3, purified immunoglobulin, buffered aqueous solution Monoclonal Anti-G3BP antibody produced in mouse clone 2F3, purified immunoglobulin, buffered aqueous solution		100μG	￥78600	2024-03-01	購入
Sigma-Aldrich Japan	SAB4500043	affinity isolated antibody Anti-G3BP-1 antibody produced in rabbit affinity isolated antibody		100μG	￥97700	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	G6046	Anti-G3BP antibody produced in rabbit ~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution ~1.0?mg/mL, affinity isolated antibody, buffered aqueous solution		200μL	￥111000	2024-03-01	購入
Sigma-Aldrich Japan	AV37713	IgG fraction of antiserum Anti-G3BP antibody produced in rabbit IgG fraction of antiserum		100μL	￥47900	2024-03-01	購入

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 化学特性,用途語,生産方法

使用

Anti-G3BP antibody produced in rabbit has been used in co-immunoprecipitation assay.

一般的な説明

G3BP is a RNA-binding protein that contains a RNA binding domain, the RRM-type domain, at the carboxyl-terminal. The N-terminal domain is homologous to nuclear transporter factor 2 (NTF2) and the central domain is rich in acidic residues. The RRM domain is involved in the binding of G3BP to specific RNA sequences. This helps G3BP to function as a CA dinucleotide-specific endoribonuclease. G3BP′s subcellular localization and protein-protein interactions are mediated by the phosphorylation of G3BP at Ser¹⁴⁹, near NTF2-like domain. G3BP is found in abundance in many kinds of malignant tumors such as lung, colon, gastric, and breast cancer.

Biochem/physiol Actions

G3BP (Ras-GTPase-activating protein SH3 domain binding protein 1) is a endoribonuclease that is phosphorylation-dependent and specific to single strand. It cleaves between cytosine and adenine (CA). It binds to the SH3 domain of RasGAP. It forms a link between RasGAP-mediated signaling pathway and RNA turnover. G3BP is required for the assembly of stress granules (SGs), which are involved in the regulation of mRNA metabolism during stress. It may be used as a cytoplasmic SG marker.

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 上流と下流の製品情報

原材料

準備製品

Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Shanghai guandao biology engineering co., ltd	18818239863	3171921642@qq.com	China	9260	58

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• Anti-G3BP antibody produced in rabbit
• Anti-phospho-G3BP (pSer149) antibody produced in rabbit
• Anti-G3BP1 antibody produced in rabbit
• Monoclonal Anti-G3BP antibody produced in mouse
• Anti-G3BP1, Anti-GAP SH3 domain-binding protein, Anti-HDH-VIII, Anti-human DNA helicase VIII, Anti-Ras-GTPase-activating protein SH3-domain binding protein 1
• Anti-GAP SH3 domain-binding protein
• Anti-HDH-VIII
• Anti-human DNA helicase VIII
• Anti-GAP SH3 domain-binding protein 1
• Anti-G3BP1
• Anti-Ras-GTPase-activating protein SH3-domain binding protein 1
• Anti-ATP-dependent DNA helicase VIII
• Anti-Ras GTPase-activating protein-binding protein 1
• Anti-Ras-GTPase-activating protein SH3-domain-binding protein