ベンセラジド

ベンセラジド 化学構造式
322-35-0
CAS番号.
322-35-0
化学名:
ベンセラジド
别名:
ベンセラジド;rac-1-[(R*)-2-アミノ-3-ヒドロキシ-1-オキソプロピル]-2-(2,3,4-トリヒドロキシベンジル)ヒドラジン;セラジド
英語名:
2-Amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propionohydrazide
英語别名:
BENSERAZIDE;Serazide;Levodopa Impurity 8;BENSERASZIDE;Benzyserazine;BenserazideBase;evodopa and Benserazide;dl-seryltrihydroxybenzylhydrazine;evodopa and Benserazide USP/EP/BP;2-(2,3,4-trihydroxybenzyl)hyrazide,dl-serin
CBNumber:
CB3384419
化学式:
C10H15N3O5
分子量:
257.24
MOL File:
322-35-0.mol

ベンセラジド 物理性質

沸点 :
574.2±50.0 °C(Predicted)
比重(密度) :
1.541±0.06 g/cm3(Predicted)
酸解離定数(Pka):
9.40±0.40(Predicted)
CAS データベース:
322-35-0(CAS DataBase Reference)

安全性情報

ベンセラジド 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

ベンセラジド 化学特性,用途語,生産方法

効能

パーキンソン病治療薬, ドパ脱炭酸酵素阻害薬

使用

Inhibitor (decarboxylase).

定義

ChEBI: A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase nhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, t causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

ベンセラジド 上流と下流の製品情報

原材料

準備製品


ベンセラジド 生産企業

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322-35-0(ベンセラジド)キーワード:


  • 322-35-0
  • 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propionohydrazide
  • 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
  • 2-azanyl-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide
  • Benserazide analogue: 1-(2,3,4-trihydroxybenzyl)-2-Methylhydrazine
  • Benserazide Metabolite: 2,3,4-trihydroxybenzylhydrazine
  • 2-aMino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide
  • evodopa and Benserazide
  • 2-(2,3,4-trihydroxybenzyl)hyrazide,dl-serin
  • dl-serine,2-((2,3,4-trihydroxyphenyl)methyl)hydrazide
  • dl-seryltrihydroxybenzylhydrazine
  • BENSERASZIDE
  • BenserazideBase
  • DL-Serine 2-[2,3,4-trihydroxybenzyl] hydrazide
  • N-(DL-Seryl)-N'-(2,3,4-trihydroxybenzyl)hydrazine
  • N1-(DL-Seryl)-N2-(2,3,4-trihydroxybenzyl)hydrazine
  • Serazide
  • Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide (7CI)
  • Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, DL- (8CI)
  • Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
  • 2-amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propionohydrazide
  • evodopa and Benserazide USP/EP/BP
  • 2-Amino-3-hydroxy-2'-(2,3,4-trihydroxybenzyl)propionohydrazide USP/EP/BP
  • Benzyserazine
  • BENSERAZIDE
  • Levodopa Impurity 8
  • ベンセラジド
  • rac-1-[(R*)-2-アミノ-3-ヒドロキシ-1-オキソプロピル]-2-(2,3,4-トリヒドロキシベンジル)ヒドラジン
  • セラジド
  • Parkinson病治療薬
  • 酵素阻害剤
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