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Remibrutinib

化学構造式
1787294-07-8
CAS番号.
1787294-07-8
化学名:
别名:
英語名:
Remibrutinib
英語别名:
LOU064;LOU-064;REMIBRUTINIB;Lou064/Remibrutinib;Remibrutinib (LOU064);Remibrutinib, 10 mM in DMSO;Remibrutinib (LOU064) ，S9660;Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide
CBNumber:
CB44675356
化学式:
C27H27F2N5O3
分子量:
507.53
MOL File:
1787294-07-8.mol

Remibrutinib 物理性質

沸点 :
634.8±55.0 °C(Predicted)
比重(密度) :
1.332±0.06 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMSO: 125 mg/mL (246.29 mM)
外見 :
Solid
酸解離定数(Pka):
11.67±0.70(Predicted)
色:
White to off-white
InChIKey:
CUABMPOJOBCXJI-UHFFFAOYSA-N
SMILES:
C(NC1=CC(F)=CC(C2C(OCCN(C)C(=O)C=C)=C(N)N=CN=2)=C1C)(=O)C1=CC=C(C2CC2)C=C1F

安全性情報

Remibrutinib 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

Remibrutinib 化学特性,用途語,生産方法

説明

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.

Remibrutinib 上流と下流の製品情報

原材料

準備製品

Remibrutinib 生産企業

Global( 71)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. 		+86-18600796368
sales@sjar-tech.com China 504 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
 marketing@targetmol.com United States 32432 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658
 sales1@artkmedchem.com China 39002 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58
Chongqing jooe co., ltd 		+86-19923400328 +86-15223382610
 info@jooe.com China 5617 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
 sales@chemhifuture.com China 5840 58
Shanghai XingMo Biotechnology Co., Ltd. +86 13524779951; 13524779951
 2075692521@qq.com China 309 55

  スペクトルデータ(1HNMR)

Remibrutinib(1787294-07-8)1HNMR
  • 1787294-07-8
  • LOU064
  • LOU-064
  • REMIBRUTINIB
  • N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide
  • Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-
  • Remibrutinib (LOU064)
  • N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide
  • Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase
  • N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide
  • Remibrutinib, 10 mM in DMSO
  • Lou064/Remibrutinib
  • Remibrutinib (LOU064) ，S9660
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