6-chloro-2-methyl-2H-indazol-5-amine
6-chloro-2-methyl-2H-indazol-5-amine 物理性質
- 沸点 :
- 365.6±22.0 °C(Predicted)
- 比重(密度) :
- 1.45±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- 2-8°C, protect from light
- 酸解離定数(Pka):
- 2.05±0.10(Predicted)
- 外観:
- 薄茶色から灰色の固体
- InChI:
- InChI=1S/C8H8ClN3/c1-12-4-5-2-7(10)6(9)3-8(5)11-12/h2-4H,10H2,1H3
- InChIKey:
- YRZNRFJEBAPCCO-UHFFFAOYSA-N
- SMILES:
- N1=C2C(C=C(N)C(Cl)=C2)=CN1C
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
6-chloro-2-methyl-2H-indazol-5-amine 価格
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6-chloro-2-methyl-2H-indazol-5-amine 化学特性,用途語,生産方法
合成
A suspension of 6-Chloro-1-methyl-5-nitro-1H-indazole (700 mg, 3.31 mmol), NH4CI (1 .59g, 29.77mmol) & Fe powder (1.66g, 29.77mmol) in a mixture of EtOH: Water (15mL: 15mL) was heated to 80°C for 6h. After 6h, TLC analysis indicated the formation of a polar spot (Ninhydrin positive). Then, the reaction mixture was cooled to RT and filtered through the celite bed; the celite bed was washed with EtOH (50mL); the filtrate was concentrated under reduced pressure to give a crude product. The crude product was purified by column chromatography (silica gel 100-200mesh) using 25% EtOAc in petroleum ether as an eluent to give 6- chloro-2-methyl-2H-indazol-5-amine (quantitative yield) as an off-white solid.
6-chloro-2-methyl-2H-indazol-5-amine 上流と下流の製品情報
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準備製品
6-chloro-2-methyl-2H-indazol-5-amine 生産企業
Global( 180)Suppliers
- 1893125-36-4
- 2H-Indazol-5-amine, 6-chloro-2-methyl-
- 6-chloro-2-methyl-2H-indazol-5-amine
- Ensitrelvir Intermediate
- S-217622-001
- 5-Amino-6-chloro-2-methyl-2H-indazole
- 6-gas-2-methyl-21-inch call-5-blad
- 6-Chloro-2-methyl-2H-indazol-5-ylamine
- 6-chloro-2-methyl-indazol-5-amine
- Atracurium Impurity 61 (Atracurium Besilate EP Impurity D)
- 6-chlorine-2-methyl-2h-Indazole-5-amine