Pomalidomide-PEG4-CO2H

Pomalidomide-PEG4-CO2H 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	901824	Pomalidomide-PEG4-CO2H	2138440-81-8	50MG	￥75900	2024-03-01	購入

Pomalidomide-PEG4-CO2H 化学特性,用途語,生産方法

使用

Protein degrader builiding block Pomalidomide-PEG₄-CO₂H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition and E3 ligase ligand.

Pomalidomide-PEG4-CO2H 上流と下流の製品情報

原材料

準備製品

Pomalidomide-PEG4-CO2H 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	9946	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068	1924344760@confluore.cn	China	2997	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
ChemShuttle, Inc.	0510-83588313-811 18800520310	sales@chemshuttle.com	China	2999	62
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51395	80
Shanghai YuanYe Biotechnology Co., Ltd.	021-61312847; 18021002903	3008007409@qq.com	China	89686	60
Shanghai Rechem science Co., Ltd.	021-31433387 15618786686	sales@rechemscience.com	China	2985	58
Aikon International Limited	025-58851090 13913916777	sales01@aikonchem.com	China	15949	58
SHANGHAI FDC-CHEMICAL CO.,LTD	021-61469567 13774476675	sales@fdc-chemical.com	China	9999	58

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• 2138440-81-8
• POMALIDOMIDE-PEG4-CO 2 H
• Pomalidomide-PEG4-CO2H
• Pomalidomide-PEG4-COOH
• Thalidomide-NH-PEG4-C2-COOH
• Propanoic acid, 3-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-
• 1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12-tetraoxapentadecan-15-oic Acid
• 1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid, Crosslinker–E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
• Poma-PEG4-COOH
• Pomalidomide 4'-PEG4-acid
• 1-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12-tetraoxapentadecan-15-oic acid
• Pomalidomide-PEG₄-CO₂H
• amine-tetrapolyethyldiol-carboxylic acid
• 1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid