1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド

1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド 化学特性,用途語,生産方法

説明

Norstictic acid is a lichen metabolite that has been found in R. farinacea and has antimicrobial and anticancer activities. It is active against A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata (MICs = 0.1-6.7 mM). Norstictic acid (1-100 μM) inhibits proliferation, migration, and invasion of MDA-MB-231 cells. In vivo, norstictic acid (15 mg/kg, i.p.) reduces tumor growth in an MDA-MB-231/GFP mouse xenograft model.

抗がん研究

Norstictic acid (NA) is a depsidone-derived metabolite common in several lichenspecies of the genera Usnea, Ramalina and Parmelia. Various biological activitieshave been reported for NA including antioxidant, antimicrobial and cytotoxic innature (White et al. 2014). Recently, Ebrahim et al. (2016) reported that administrationof NA to MDA-MB-231 cells significantly suppressed the proliferation,migration and invasion. Also, it showed minimal toxicity to non-tumorigenicMCF-10A mammary epithelial cells. They also performed molecular modelling,Z′-LYTE biochemical kinase assay and Western blot analysis, to identify c-Met asa potential macromolecular target. Further, NA treatment significantly suppressedMDA-MB-231/GFP tumour growth of a BC xenograft model in athymic nudemice. At this juncture, they concluded that lichen-derived natural products arepromising resources to discover novel c-Met inhibitors useful to control TNBC(Ebrahim et al. 2016).

1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド 上流と下流の製品情報

原材料

準備製品

1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8860	58
Shanghai Saikerui Biotechnology Co. , Ltd.	021-58000709 15900491054	info@scrbio.com	China	9661	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29547	58
Shanghai Weiyite Biotechnology Co., Ltd	15317051735	zhaojing@wytsci.com	China	9589	58
Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	6838	58

571-67-5(1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド)キーワード:

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• 571-67-5
• NORSTICTIC ACID
• BRYOPOGONIC ACID
• 1,3-Dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-7H-isobenzofuro[4,5-b][1,4]benzodioxepin-11-carbaldehyde
• 7H-Isobenzofuro[4,5-b][1,4]benzodioxepin-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-
• ノルスチクト酸
• 1,3-ジヒドロ-1,4,10-トリヒドロキシ-5,8-ジメチル-3,7-ジオキソ-7H-イソベンゾフロ[4,5-b][1,4]ベンゾジオキセピン-11-カルボアルデヒド
• 5,13,17-トリヒドロキシ-7,12-ジメチル-9,15-ジオキソ-2,10,16-トリオキサテトラシクロ[9.7.0.03,8.014,18]オクタデカ-1(18),3(8),4,6,11,13-ヘキサエン-4-カルバルデヒド
• ノルスチクチン酸