2ヒドロキシプロピルγシクロデキストリン
2ヒドロキシプロピルγシクロデキストリン 物理性質
- 融点 :
- 52-55 °C(lit.)
- 沸点 :
- 97-98 °C3 mm Hg(lit.)
- 闪点 :
- >230 °F
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- H2O: 可溶450mg/mL
- 外見 :
- 固形粉末
- 色:
- 白い
- PH:
- 6-9 (2% in H2O)
- 旋光度（Optical Rotation）:
- [α]20/D +145°, c = 1 in H2O
- InChIKey:
- WZMOWQCNPFDWPA-UHFFFAOYSA-N
- CAS データベース:
- 128446-34-4(CAS DataBase Reference)
- Absorption:
- ≤1.7 at 220-350nm in solution at 2%
≤1.7 at 350-660nm in solution at 2%
2ヒドロキシプロピルγシクロデキストリン 価格
もっと(10)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
H125 |
(2-ヒドロキシプロピル)-γ-シクロデキストリン solid
(2-Hydroxypropyl)-γ-cyclodextrin solid |
128446-34-4 |
5G |
￥29900 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
H125 |
(2-ヒドロキシプロピル)-γ-シクロデキストリン solid
(2-Hydroxypropyl)-γ-cyclodextrin solid |
128446-34-4 |
100g |
￥226000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
390704 |
(2-ヒドロキシプロピル)-γ-シクロデキストリン extent of labeling: 0.6 molar substitution
(2-Hydroxypropyl)-γ-cyclodextrin extent of labeling: 0.6 molar substitution |
128446-34-4 |
5g |
￥11600 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
390704 |
(2-ヒドロキシプロピル)-γ-シクロデキストリン extent of labeling: 0.6 molar substitution
(2-Hydroxypropyl)-γ-cyclodextrin extent of labeling: 0.6 molar substitution |
128446-34-4 |
25g |
￥30800 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
779229 |
(2-ヒドロキシプロピル)-γ-シクロデキストリン Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, ≥98.0% (HPLC)
(2-Hydroxypropyl)-γ-cyclodextrin Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, ≥98.0% (HPLC) |
128446-34-4 |
100g |
￥75000 |
2024-03-01 |
購入 |
2ヒドロキシプロピルγシクロデキストリン 化学特性,用途語,生産方法
化学的特性
white powder
使用
For R&D use
一般的な説明
(2-Hydroxypropyl)-γ-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.
生物活性
(2-Hydroxypropyl)-γ-cyclodextrin (HPγCD) is a water-soluble alkylated cyclodextrin derivative. It has pharmaceutical potential as it may aid in enhancing the solubility of drugs for oral dosage preparations or formulations. It solubilizes macromolecules, such as cholesterol. It is like β cyclodextrin but solubilizes larger molecules. It favors lysosomes distribution across the cytoplasm and can modulate lysosomal dynamics and participates in lysosomal homeostasis. HPγCD treatment promotes a wide distribution of lysosomes across the cytoplasm in NPC1 patient-derived fibroblasts. In contrast, lysosomes are clustered near the cell center in untreated cells, raising the possibility that HPγCD has the potential to modulate lysosomal dynamics and functions[1]. In the Niemann pick disease model, HPγCD reduces cholesterol accumulation. Industrially produced HPγCD, which is used as a complexing agent in new ophthalmic formulations, is not a single compound but a heterogeneous, complex mixture of homologues and isomers substituted by a variable number of 2-hydroxy-propyl groups at different positions of the sugar moieties[2].
2ヒドロキシプロピルγシクロデキストリン 上流と下流の製品情報
原材料
準備製品
2ヒドロキシプロピルγシクロデキストリン 生産企業
Global( 227)Suppliers
2ヒドロキシプロピルγシクロデキストリン スペクトルデータ(IR、Raman)
128446-34-4(2ヒドロキシプロピルγシクロデキストリン)キーワード:
- 128446-34-4
- g-Cyclodextrin, 2-hydroxypropylethers
- Cavasol? W8 HP
- (2-Hydroxypropyl)-gamma-cyclodextrin produced by Wacker Chemie AG, Burghausen, Germany
- (2-Hydroxypropyl)-gamma-cyclodextrin Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, >=98.0% (HPLC)
- (2-Hydroxypropyl)-gaMMa-cyclodextrin extent of labeling: 0.6 Molar substitution
- HYDROXYPROPYL-GAMMA-CYCLODEXTRIN (HGC) 4 5% W/V SOLUTION IN H2O
- HYDROXYPROPYL-GAMMA-CYCLODEXTRIN, MS=0.6
- .gamma.-Cyclodextrin, 2-hydroxypropyl ethers
- CAVASOL(R)W8
- (2-Hydroxypropyl)-γ-cyclodextrin,HGC
- (2-Hydroxypropyl)-gamma-cyclodextrinsolid
- (2-Hydroxyapropyl)-gamma-cyclodextrin
- HP-gamma-CD
- HPGCD
- (2-Hydroxypropyl)-γ-cyclodextrin (Technical Grade)
- Hydroxypropyl-Gamma-Cyclodextrin with good quality and stable supply
- (2-Hydroxypropyl)-gamma-cyclodextrin,average Mw ~1，589
- HydroxypropyI Gamma Cyclodextrin
- γ-Cyclodextrin, 2-hydroxypropyl ethers
- Calcium Dobesilate Capsules
- (2-hydroxypropyl)-γ-cyclodextrin
- (2-Hydroxypropyl)-gamma-cyclodextrin (Technical Grade)
- (2-Hydroxypropyl)-gamma-cyclodextrin (DS~4.5)
- HYDROXYPROPYL-Y-CYCLODEXTRIN
- 2-FLUORO-4-METHYL-1-NITROBENZENE
- HP-γ-CD
- HP-γ-Cyclodextrin
- Hydroxypropyl-γ-Cyclodextrin
- 2ヒドロキシプロピルγシクロデキストリン
- (2-ヒドロキシプロピル)-Γ-シクロデキストリン
- シクロマルトオクタオースの(2-ヒドロキシプロピル)エーテル化反応生成物