6-メチルキノリン 化学特性,用途語,生産方法
外観
わずかにうすい黄色～暗赤褐色、液体
用途
香料・香辛料
化学的特性
6-Methylquinoline is a clear light yellow to light orange liquid that has a pungent, heavy odor. dissolved in 4 volumes of 50% ethanol or 60% ethanol of the same volume and in oily fragrances. May be synthesized from p-amino-benzaldehyde and acetone.
天然物の起源
Reported found in Finnish and Japanese whiskey.
使用
6-Methylquinoline can be used as primary carbon source in culture of Pseudomonas putida QP1. 6-Methylquinoline was used in the synthesis of fluorescent halide-sensitive quinolinium dyes and fluorescent probes for determination of chloride in biological systems.
主な応用
6-Methylquinoline, is a building block used for the synthesis of various pharmaceutical compounds, and biologically active compounds. It can be used for the preparation of pyranobenzopyrone compounds, having anti-norovirus activity.
一般的な説明
Clear pale yellow liquid or oil with a quinoline odor.
空気と水の反応
Insoluble in water.
反応プロフィール
6-Methylquinoline is sensitive to prolonged exposure to light. May react vigorously with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
火災危険
6-Methylquinoline is probably combustible.
合成
6-Methylquinoline is obtain from coal tar, by synthesis from p-aminobenzaldehyde and acetone.
純化方法
Reflux it with BaO, then fractionally distil it. Further purified it via its recrystallised ZnCl2 complex (m 190o). [Cumper et al. J Chem Soc 1176 1962, Beilstein 20 III/IV 3498, 20/7 V 400.]
6-メチルキノリン 上流と下流の製品情報
原材料
準備製品