スピロキサミン標準品 化学特性,用途語,生産方法
外観
ごくうすい黄色～黄褐色、澄明の液体
溶解性
アセトン及びエタノールに溶け、水にほとんど溶けない。
用途
Δ14-レダクターゼ・Δ8→Δ7イソメラーゼ阻害剤ムギ類のうどんこ病・さび病，ブドウのうどんこ病などの防除に使われる
農薬用途
殺菌剤
説明
Spiroxamine is a tertiary amine fungicide and an inhibitor of Δ
14 reductase/Δ
8→Δ
7 isomerase. It inhibits the growth of
N. parvum,
B. dothidea,
D. seriata, and
L. theobromae isolates from grape vines (EC
50s = 0.97-10.28 mg/L). Spiroxamine (0.03-30 μM) reduces network formation in rat cortical cultures. It is also cytotoxic to MDA-kb2 cells (EC
20 = 9.29 μM).
使用
Spiroxamine is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.
定義
ChEBI: The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powde
y mildew in the production of cereals, bananas and grapes.
作用机制
Δ14-レダクターゼおよびΔ8→Δ7イソメラーゼを阻害し防除活性を発揮する
代謝経路
Spiroxamine is metabolized rapidly in plants, soils,
water, and animals via similar degradation pathways.
The metabolic pathways include hydrolysis and
oxidation at several places in the molecule. Side
chains are also degraded to various water-soluble
conjugates in animals and in plants, and at the end of complete degradation to natural constituents, carbon
dioxide is formed in soils as the principal metabolite.
The favorable sorption characteristics rule out any
possibility of appreciable translocation in soil. In wheat,
the total residue is determined in forage, grain, and
harvest-ready straw. In the field studies, the residues in
the grain are mostly below 0.05 mg kg
-1, and only in a
few cases up to 0.3 mg kg
-1. In the milk of cows
ingesting spiroxamine residues with the feed, no
residues are found in the least favorable case. In eggs
of laying hens, the residue concentrations are below the
limit of quantification. There are no residue
concentrations detected in the hen fat, meat, and liver.
スピロキサミン標準品 上流と下流の製品情報
原材料
準備製品