1-Indanone is an important skeletal structure with a wide range of biological activities. Extensive research has demonstrated that 1-indanone derivatives play a significant role in the development of drugs for the treatment of Alzheimer's disease, as well as in anti-diarrhoeal, anti-proliferative, antibacterial, anti-inflammatory and anti-cancer agents[1].
화학적 성질
Pale yellow liquid
용도
1-Indanone is an oxidation product of Indan, a component of fuels, solvents, and varnishes. 1-Indanone is also a metabolite of Thalidomide that has been shown to inhibit the attachment of tumor cells to concanavalin A coated plastic surfaces.
정의
ChEBI: An indanone that consists of 2,3-dihydro-1H-indene substituted by an oxo group at position 1.
Synthesis
1-Indanone is produced by cyclization of be{a-Phenylpropionyl chloride in Benzene.
