플루미클로락-펜틸

플루미클로락-펜틸
플루미클로락-펜틸 구조식 이미지
카스 번호:
87546-18-7
한글명:
플루미클로락-펜틸
동의어(한글):
플루미클로락-펜틸
상품명:
FLUMICLORAC-PENTYL
동의어(영문):
pentyl-[2-chloro-5-(cyclohex-1-ene-1,2-dicarboxamido)-4-fluorophenoxy] acetate;S 2303;V 23031;S 23031;RESOURCE;SUMIVERDE;Pentyl ester;Flumiclorac-pe;fluMiclorac-penty;FLUMICLORAC-PENTYL
CBNumber:
CB6141035
분자식:
C21H23ClFNO5
포뮬러 무게:
423.86
MOL 파일:
87546-18-7.mol

플루미클로락-펜틸 속성

녹는점
90-91℃
끓는 점
558.0±50.0 °C(Predicted)
밀도
d20 1.3316
저장 조건
0-6°C
산도 계수 (pKa)
-2.32±0.20(Predicted)
EPA
Flumiclorac-pentyl (87546-18-7)

안전

HS 번호 29251900
독성 LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Kamoshita)

플루미클로락-펜틸 C화학적 특성, 용도, 생산

용도

Flumiclorac-pentyl is a herbicide.

Synthesis

Flumiclorac-pentyl is produced via a 5–6 step synthesis that commences with the preparation of the hexahydrophthalic anhydride core through Diels-Alder cycloaddition of maleic anhydride with cis-1,3-butadiene under high-pressure conditions in benzene, followed by ring opening to the diacid and condensation with methylamine in water to form N-methyl-hexahydrophthalimide. This imide is then lithiated and coupled via nucleophilic substitution to 2-chloro-4-fluoro-5-nitrophenyl acetate. Reduction of the nitro group using yields the amine intermediate, which undergoes intramolecular cyclisation with the acetate to form the cyclic imide.

신진 대사 경로

In the feces and urine of rats, more than 90% of administered 14C-flumiclorac pentyl is excreted within 48 h of treatment. Flumiclorac pentyl is rapidly and extensively metabolized. The major fecal metabolites are identified as the sulfonic acid conjugates, and the major urinary metabolite is identified as 5-amino-2- chloro-4-fluorophenoxyacetic acid. The metabolic reactions include cleavage of the ester linkage, cleavage of the imide linkage, hydroxylation and following reduction at the cyclohexene ring of the cyclohexene- 1,2-dicarboxylic acid moiety, and incorporation of a sulfonic acid group into the carbon carbon double bond of the 3,4,5,6-tetrahydrophthalimide moiety.

플루미클로락-펜틸 준비 용품 및 원자재

원자재

준비 용품


플루미클로락-펜틸 공급 업체

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